Simvastatin toxicity
Common Questions and Answers about Simvastatin toxicity
vytorin
there are trials already i posted in the past, also the effect of sim on liver was reviwed by liver researchers and they said it has no toxicity the elevations of alt that can happen on few are due to a balance of lipids not toxicity because the alt elevation is transient and resolve itself
the only serious side effect of sim that can happen is muscle damage or mitocondrial discorder, very rare
statins cause acute liver failure in chronic hbv patients?
entecavir lowers hbvdna and replication, so number of circulating virions but cannot stop virions and replication complitely
simvastatin, makes weak virions so maybe replication can be lowered so much or stopped complitely and fasten cccdna and hbsag lowering
nitazoxanide, acts lowering hbsag
it is also good to note that etv and ntz has no sides, and also simvastatin has almost no sides (only less than 1% develops sides on liver) and studies on sim on cirrhosis have found lower liver cancer ra
this is what trials found while what they say on the drug is not supported by trials and not supported by liver experts
the high dose have had extremely rare rise of alt which dont mean liver damage as we now know, in any case just as a extra safety check alt/ast and creatinine monthly, if you get an alt rise we must then check if it is immune activation and lowering of hbvdna and hbsag or drugs toxicity and this is simple if alt rise a lot (over 200) and hbsag and hbvdna rise or stay stable fo
Since it is an azole i was concerned and looked up the drug and sure enough liver toxicity is one of the possible sides.
http://livertox.nih.gov/Metronidazole.htm
Anbody know if i should take it? Or just to be safe stick with good old penicillin?
peg+simvastatin+alinia+vit d3 and possibly tenofovir too, this will improve hbsag clearance veyr very much because peg monotherapy has only hbv clearance of 8% in 48 weeks, too low
heptech products are all ok except fibroguard, you shpuld not take fibroguard as lon as you are on peg
also statins like simvastatin were reported to boost response a little but better not mix 2 statins, in a report researchers of ezetimibe effect on hbv and hcv suggested the use of ezetimibe with interferon but without simvastin
ezetimibe dose is 10-20mg daily but human trials with dose 50mg daily for a limited time did not find any sides or toxicity
surgery, but while recovering, the inflamed joints in my hands and wrists were much more painful than the surgery. I am certain I had toxicity to the drug simvastatin. Just days after quitting it my hands were just sore, not inflamed, much better. The best thing to relieve the symptoms has been Nonni. It helps me sleep at night and soothes my joint pain.
I'm on Simvastatin (40mg) which have some nasty side effects, like cramps and muscle spasms. Can you reommend an alternative?
Can someone explain what, if any, evidence there for a switch from simvastatin to pravastatin? My husband's doctor said there is new evidence that simvastatin may be detrimental. Unfortunately, my husband did not quiz him further. He already has one stent in a narrow back artery but he has brought his cholesterol down considerably with the statins.
Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).
curious if stef2011 or studyforhope or StephenCastlecrag know whether simvastatin by itself can reduce viral load? I've read about the effects in conjunction with NUCS but I'm curious if sim is effective alone.
I have been taking simvastatin for three weeks since having a Tia but have also had a flu like cold for ten days , I am still having aching flu like pains which I would have thought would have passed by now . I don't know if this is a side effect of the drug I'm taking 40mg a day but feel really achy will this pass .
Zosta -10) also has the same effect as Storvas 10 mg. I have had cholecystectomy about 5 years back.
I have been taking Simvastatin 20mg for about 2 years, but recently my bad cholesterol has gotten very high to where it is elevated. Now, I admit to not being consistent lately with taking my medication; could this be the cause for my cholesterol to skyrocket?
The use of simvastatin in the prevention of a malignant liver tumor according to the present invention contemplates the daily administration of an effective amount of simvastatin orally. An effective amount of simvastatin is that amount which provides a decrease in the level of alphafetoprotein to a normal level and which maintains alphafetoprotein at the normal level.
Warnings and Precautions
Because simvastatin can affect the liver, it is used with caution in people who drink more than a moderate amount of alcohol or have a history of liver disease.
Simvastatin is not recommended for people with liver disease or high liver enzymes before treatment begins.
Possible Symptoms of Liver Problems
Several symptoms can occur in someone who develops liver problems while taking simvastatin.
I've been taking 80 mg simvastatin daily for the last 8 years, will tis be tha cause of an elevated GGT reading of over 350?
The doctor is switching me to simvastatin which reacted badly with my liver in the past. Aim is to save money. Is it safe to buy Atorvastatin online ?
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