“If you are unaware that a patient is on simvastatin and you give either boceprevir or telaprevir, the simvastatin level in the blood can go high and patients can develop muscle breakdown,” said Dr. Jensen.
http://www.idse.net//ViewArticle.aspx?
Patients were put on a cholesterol-lowering diet and given one of the medications. After 18 weeks, patients given simvastatin had significantly lower total cholesterol, lower LDL, lower triglycerides, and higher HDL cholesterol levels than those who took pravastatin. The study found that the patients on simvastatin achieved the target LDL level of less than 130, more than those on pravastatin (65 percent on simvastatin versus 35 percent on pravastatin).
The risk of any side effect is anywhere between 2% and 5% which classifies this as very safe. Common side effects are muscle pain and sore joints. I would take it and just keep an eye out for anything that may be a side effect. This link will tell you what to look for;
http://www.emedicinehealth.com/drug-simvastatin/article_em.
I quit taking the simvastatin last tuesday, and by friday I looked perfectly normal with no steroid cream......
Thanks again for all the help!
My endocrinologist prescribed me Atorvastatin 40mg in place of the simvastatin but it has since given my major chest pain and muscle weakness in my fingers and legs; so I was advised by the pharmacist to stop that and I have only taken the new statin twice and tonight was the second time taking it.
Is simvastatin something that can be eased up to a higher dose to do the exact same thing atorvastatin does for the bad cholesterol?
Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).
My wife is taking Morphine and Oxycodone for chronic back pain from a vertebral fracture 2 years ago (repaired) and herniated disks. She is finding that her hair (which has always been very thick and healthy) is thinning dramatically. She is also taking Simvastatin and an anti-depressant, Citalopram, and an amphetamine for ADHD. Is hair loss a normal side effect of these meds, and, if so, what can be done to combat the problem?
Simvastatin has been wdely used by members on this forum including myself. Took it for a few months but not currently taking it at the moment. So yes,Simvastatin, and overall a very healthy diet!!!!
I use simvastatin to lower the cholesterol and lisinopril to lower the bp. The lisinopril works w/o the simvastatin and v.v.
Amlodipine is a calcium channel blocker while lisnopril is an angiotensin converting enzyme(ACE) inhibitor. Both groups of drugs and simvastatin are unlikely to cause erectile dysfunction. However yes, all three of them can cause swelling of ankles. Talk to your doctor. You can change your medications. Among antihypertensives you need to avoid thiazides , beta blockers and alpha blockers.
High blood pressure and reduced blood supply to penis can also cause erectile dysfunction.
I have been on 20 mg of simvastatin and 3000 mg niaspan now my ck levels have went from 60 to 295 i could hardly walk .will my levels come down if i lower dose. and reverse damage. i have 12 stents .the rest of my blood work is fine.
Problem is I think if you can't take one statin you may not be able to take any. But there are other drugs you can try like Niaspan (slow release niacin) and vitorin and so forth. I don't know if you are into changing your diet but if you get a chance watch the video Forks over Knives. It is how a plant based diet can reverse althroschlerosis. My husband's cholesterol was 260, blood pressure was 140/90 and weight 260. He is 6' 2" though.
Warnings and Precautions
Because simvastatin can affect the liver, it is used with caution in people who drink more than a moderate amount of alcohol or have a history of liver disease.
Simvastatin is not recommended for people with liver disease or high liver enzymes before treatment begins.
Possible Symptoms of Liver Problems
Several symptoms can occur in someone who develops liver problems while taking simvastatin.
There is only one interaction that would be of any concern. Treatment with both simvastatin and niacin may result in muscle pain or tenderness or muscle weakness.
Using simvastatin together with niacin is usually not recommended, but may be required in some cases. If you are using both medicines together, your doctor may change the dose or how often you use one or both of the medicines. It is important to tell your doctor and pharmacist about all other medicines that you are using.
On a recent blood test my potassium level was above normal. I stopped taking simvastatin. After 3 months I took another blood test and now my cholesterol level has risen to 6.5. What shall I do. I am seeing my Doctor next week.
If you are in the construction industry, it is more likely that you have this condition. The knee pain and sole pain may be due to statin, check with your doctor, and he may reduce the dosage.
Regarding COPD, have a look at the following site:
http://www.uptodate.com/patients/content/topic.do?topicKey=~mD..
Needless to say, they released me this morning and prescribed lopressor, norvasc, protonix, and simvastatin and 325 mg of ecotrin a day. I need to go back to the cardiologist in two weeks, but I'm kind of clueless as to what happened with me. I'm 48 and I'm an ex-smoker. The doctor did say after the angiogram that he didn't think the pain I experienced was cardiac in nature and they are suggesting I see a digestive disease doctor.
We have been on simvastatin for (wife for 1+ years, me for 2+ years) and stopped about 5-6 months ago - wife still having pains in the butt some dizziness and leg pain, but getting better - I am having butt pain and leg pains, swollen left knee, (but joint pain seems OK on stairs), recovery seems slower than my wife's. But both of us have just been diagnosed with right enlarged renal cysts which were not there before taking simvastatin.
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