rebif titration pack

INTERESTING, I DID NOT READ THIS INFO FROM THE FDA ABOUT THE DOSING. THOUGHT AS "T" SAYS THAT IT'S STANDARD TO WORK TOWARD THE 44's. I WOULD LIKE TO KNOW MORE ABOUT IT THOUGH, AS WEIGHT DOES AFFECT MEDS, AND IF REBIF IS ONE OF THEM, YOU'D THINK IT WOULD BE MORE KNOWN. LEAVING ME TO THINK IT'S NOT AN ISSUE. I WAS PRESCRIBED THE 44's (TITRATION PACK 1ST) AND AM THIN ALSO. . ..HMMM SEEMS THIS IS JUST SOMETHING TO FIND OUT MORE INFO ABOUT.

Hi, I just began my titration of Rebif, with 8.8 mcg for 2 weeks, so I moved up to 22 mcg on Friday, January 29th. So far, my side effects were flu like symptoms and increased tremors (with 8.8 mcg). Today, Saturday 30th, my side effects include flu like symptoms, extreme aches and pain throughout my body, all the way down to my bones, like I have been beaten severely with a baseball bat, but also I'm running a fever. Normal body temperature for me is 96.

My neuro likes to keep patients on the 22mcg dose longer than the 2 weeks in the titration pack, to get acclimated to the med. Ask your doc about that. My neuro tests for liver, etc bloodwork at 3, 6, & 9 months -- I asked for more frequent tests -- monthly for the first 6 months. I also have thyroid disease, take Lipitor, and have a history of depression, so had some extra fears about taking Rebif -- but so far, no problems there.

Hi. I've just finished the titration stage and am now on 44 dose of Rebif using the rebismart. As the dose increased I've had really bad stinging like a bee sting when the drug starts going in. I'm starting to dread the injections already. I would be very grateful for any tips to reduce the sting as I'm a newbie to this. Many thanks, Sue.

Well I did my first injection and it was absolutely fine! As I mentioned though I am starting on just 4mcgs (half the lowest dose) as my nurse wants to increase the dose gradually. I'll then go on to 11mcgs (ie half of the next dose in the titration pack) and then I start the 22mcgs dose on 26th June and then we'll see how I'm tolerating it particularly with depression and then they might put me on the max dose of 44mcgs.

I took Rebif (very similar) for a while, and I made sure of a couple of things - I took 400mg Ibuprofen just before I took my shot, and I took my shot just before bed. Most of the time when I woke up, I felt fine. Occasionally I still felt a little "flu like" in the morning, and I just took a little more Ibuprofen and I was good to go. The rest of the next day went fine. Good Luck!

I started Rebif in January on the titration pack, everything was good, minimal side effects. Ive been up to 44s for a while now and I have just started getting some site reactions. Not every time, my belly and thighs seem to be more reactive. Until about 5 minutes ago I thought they were limited to red, tender spots and bruising but now I have found an area on my thigh that appears to have a large (3 inch?) knot deep under the skin. It doesnt hurt, Its not red, but it is pretty solid.

That is too bad - I was hoping after your long wait you would have good luck with the first one and being able to stick with it. It is in the back of my head that I heard a doctor put Avonex as the less potent of the interferons, but I may be wrong. If that is true, I think I would step up to Rebif. Did your doctor offer any ideas or can you schedule an appt with the MS nurses and discuss it further?

The flu-like symptoms that you will hear about do happen, however, I have to say that the titration pack they start you out with really helps to prevent (my belief) major flu-like symptoms. They start you out with a very low dose (8.8mgs) and gradually work you up to the full 44mgs. It was not all that bad for me, though as I'm sure you are aware, people have different reactions to meds all the time. Good thing is if you get the flu-like symptoms early on, they do start to diminish.

I was given a prescription for Rebif near the end of the steriod titration. I have labs done every three months to keep an eye on how it affects things. Everyone is different as far as what DMD they will best tolerate. I have had past history of depression, although it had lifted some before going on the Rebif, and that may be why I am tolerating it fairly well. I do use the Rebiject autoinjector, though I have had to do two manual injections when the injector malfunctioned.

My injections are going okay I think. I started with the titration pack, so yesterday was the last dose of the 8.8 and tomorrow starts the 22. My side effects from the rebif have been very mild but that may be due tho the crazy amount of anti-inflammatory meds i take. Up until yesterday I had reached a nice state of very mild tingling and numbness that only reared its ugly head when I got pretty active.

I have neuropathic pain down my arms, and in my hands and feet. Recently my Doctor gave me a titration pack of Savella to try. Savella is a medication used for the pain associated with Fibromyalgia. I noticed a reduction in the pain, burning and stinging sensation in my feet and hands even at the initial dose after the first few days. I also, bizarrely enough, noticed an improvement in my ability to urinate and empty my bladder.

I have been taking Rebif injections, since January 2010, and I have never missed a single one, until now. Up until January 1, 2012, I have received my Rebif injections, free of charge, due to the fact I had no health insurance. I became eligible for Medicare, on January 1, 2012, and so I have had to wait for MS Lifelines to decide whether I'm still eligible for their "free of charge" program.

Does anyone out there know of a good doctor for FM? I am so tired of the trying this and trying that. I am currently on Savella with the 2 week titration pack. I haven't noticed any difference as of yet, it's only been 3 days.

Has anyone else experienced some incredible, ever-lasting bruising at their injection sites? I've been on a titration dose for about 5 weeks now and I can still see the the bruise from my first injection. A majority of the other injection sites are red blotches that are about 2 inches in diameter. These marks are mostly visible on my thighs and stomach. Sometimes I get a little residual pain and a red welt.

Hi all- I am just writing to let everyone know that I am about to start tysabri infusions in late June. My neurologist thought that based on the "large lesion load" in my t-spine that Rebif was simply not working for me. Because I am young, and he wants to "give me the best chance" for quality of life he thought tysabri is the best choice for me (despite the risky side effects).

Hi there:) I just spent three weeks trying very hard to get my body acclimated to Savella because I didn't think that Lyrica was helping. I'd start a titration pack.....get to the 50 mg. oval tablets, and break them in half and sometimes into quarters. I'm convinced that the effect Savella has on norepinephrine was why I couldn't take it.I would get so incredibly anxious and nervous......I don't think that my body needs any boost to my norepinephrine.

My doctor switched me to lyrica/savella,and I am on day 11 of the titration pack. without any bad effects. My energy has increased, and I hope that continues,and my pain has been helped alot.

Last night I proceeded to do my 4th Rebif injection and wasted an entire syringe because I stupidly forgot to remove the cap. By the time I realized what I was doing it was too late; I pulled the end off of the autoinjector and the medicine came shooting out. Aargh! This happened with my first shot when the nurse was instructing me. She also forgot to tell me to pull off the cap remover so the very first syringe was ruined.

When I went to get my rebif refilled last week was tokd they were out and its on border and they don't kniw when it will come in and could be a couple months. I called every pharmacy in town and got.same.story. Then called rebif and they know.if.no shortage. Is anyone else.having this problem? In meantime I am out so no shots.

am anticipating a call from my neuro tomorrow and though technically the PA couldnt give me a diagnosis at my last appt cuz the doctor was not available I am about 99% sure of what he is going to say...He's already had me research the different DMD's and told me at my 1st appt he wanted them started right away though I never really got an "official" diagnosis. I am leaning towards rebif and thats the one they suggested for me..

Hi, Laura. I've been on Rebif, 4 and 1/2 months. I started on Copaxone, but after 6 and 1/2 weeks, we found out that my "side effects", were actually a severe allergy to it, The Rebif auto-ject is easy to use, and has the finest needle. I don't even feel it go in. And that is saying something, because I am 5'2 and weigh 77#s. I take an Advil for Migraines 1/2 hour before I inject. (I didn't get them until I was on it for just over 3 months.

I had to titrate back up to the full dose much more slowly and then no more GI issues. I think a lot of neuros have adopted a slower titration than Biogen recommends (one week half dose then full dose after that I think). I started in May and had issues around week 2-3 then had to bounce back to starter dose. Took me until Aug/Sept to get things squared away with that side effect.

Rebif titration pack

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