My current dose is Prograf 3 mg AM/ Prograf 3 mg PM and Rapamune 4 mg AM. The intent is to convert me to 100% Rapamune because of the nephro-toxicity of the Prograf and my young age and because of the anti-cancer properties of Rapamune. Data, while horribly limited, has shown Rapamune's anti-cancer properties have had success against vascular tumors such as mine so EHE, in this case chronic, is part of the cancers Rapamune affects (some cancers it has no effect).
Was on Rapamune (5mg a day) prior to hernia surgery and then week before hernia surgery was put on Prograf (4mg a day) and taken off the Rapamune. I have been on Progaf since hernia surgery (8 weeks ago). Due to high billirubin reading of 28, I have been put on one Rapamune pill a day. I never had such a high reading prior to being put on Prograf, I'm going into hospital tomorrow for moderate rejection. Sine I'm on 4mg of Prograf and 1mg of Rapmune a day, could I be over medicated?
everything was great for first 7 mths. Then they changed his transplant meds from prograf and cellcept to rapamune and cell cept. Thats when it all went bad. He went into resp. arrest 4 times in 1 month, kidney failure, acted like he was drugged, twitched, and spent many weeks in the hosp. We tried to tell the docs that it was the new meds, he was also on vancomycin, and they would not listen they kept saying it was the pain meds he had been taking for years but we knew better.
5mg Prograf bid, Rapamune 3 mg daily, 15 mg prednisone, Cellcept 500 mg qid. The nausea and vomiting has been very hard for him to deal with, and my guess is that increasing the immunosuppression will only worsen those symptoms.
The most recent ERCP done last week showed a 6mm discrepancy between the donor and recipient bile ducts with an impression of primary vs secondary sclerosing cholangitis.
Its kind of the same feeling i had after my transplant when i was on hi doses of prograf. Any ideas ? Can i try lowering my prograf to try and alievaite this cognitive impairment by adding maybe some cellcept? I have never been on anything but prograf alone except prednisone 6 mo tx .My mouth stays extreamly dry tounge seams to be affixed to my roof of mouth with a tight jaw week muscels and eyesight since contrast. nobody seems to be able to offer any direction.
I'm 61 years young and had a full liver transplant 2 1/2 months ago. Prograf levels go from 7 to 13.6 back to 6.5 Could it be the new lab that is screwing up. I take all 52 pills on time dailywith a wonderful hubby making sure.
I went into rejection twice in the hospital and because of this my transplant team saw it best to put me on 5mg of prograf twice a day as well as 4 mg of rapimune, which by the way was off label and i had to sign a release form for. Just within the past 2 months they lowerd my dosage of rapimune to 2mg but kept the prograf the same. My question to you is exactly how suppressed is my immune system?
I have taken prograf and cellcept for 12 yrs. A month ago I went nito renal failure.The kidney Dr. said it was from the prograf that this happened. The liver Dr.disagrees and is putting me back on prograf lower dose. I have been taking prednisone in the mean time . Kind of worried this will happen again. Anyone else have this problem in the past and what was done about it .
Thanks , any input would be welcome !
typically prograf doesnt cause thirst although any medication can cause anything in any person
I am 6 years post liver transplant from genotype 3 Hep C. My doctors want to start treatment to clear the virus. I take Prograf for the liver transplant and I know Naragenin affects the Prograf levels. My question is if during treatment I also took Naragenin and my prograf levels were closely watched and adjusted for the Naragenin effects, wouldn't I have a better chance of clearing the virus.
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