m going to have to go through my supplements and meds. The only new med is the Pramipexole .05 twice a day (Mirapex). The supplements are Sam-E, D 2000, A and Magnesium 250 twice a day. I'm going to cut the Pramipexole to once a day. Does anyone see if any one of these would cause this or is there a virus going around?
Has anyone tried Pramipexole (Mirapex, Mirapexin, Sifrol) for chronic pain? I have had low back pain for about 15 years now. I finally got someone to do an MRI back in June (I think, it was slightly before summer 2016) and they found a herniated disc at L4-L5 and a degenerated disc at L5-S1. The neurosurgeon decided surgery wasn't worth the risk and pain treatment was the best option.
Has anyone used a patch? The only med I take is pramipexole.
Hi, I am not Trin but I also have / had PCT. There are specific tests to diagnose PCT which my dermatologist did. AS far as myself and Trin the manifestations were large liquid filled blisters that made a mess nof our hands. The blisters were like a burn that filled with a clear liquid. In my case it did not start with a rash but only the blisters. The blisters hurt so bad, almost to the bone hurt. Trin will chime in here I am sure of that and she is better able to put into words tham me.
Guess I should say PCT skin manifestations return after tx as the PCT is chronic anyway. I also should spell it correctly "porphyria" (I think).
The next step is cirrhosis so I had to start treatment as soon as my PCT was in check. PCT is chronic, not really any cure, but the doctor said treat the hepc and the PCT will go away and it has so far. If I can answer any other questions, please ask. I feel I am somewhat knowledgeable in this area and will share any information I can. Another one of our memeber GSgirl also had PCT and she may lend some expertise as well.
If you haven’t begun treatment for HCV yet, this might be something called ‘PCT’ or ‘Porphyria Cutanea Tarda. It typically manifests as blisters on the upper body, particularly in those areas that are in contact with the sun. it is also strongly associated with Hep C.
It involves iron management by the liver, and may require phlebotomy, or bloodletting, to help resolve it. Look for small blisters on sun-exposed areas; they may leave small scars as they heal over.
From what you are describing it sounds like an extra hepatic manifestation associated with hepc called Porphyria Cutanea Tarda (PCT). Essentially, what happens is because of the hepc the liver does not process iron properly. See your doctor and have phlebotomy sessions (blood letting) scheduled to treat the Porphyria. Phlebotomy reduces ferrtin levels and generally the Porphyria will subside.
Here is a link which explains PCT.
http://www.porphyriafoundation.
My husband is taking clonazepam .05, Lomtrigine 200 mg and pramipexole dihydrochloride 0.25 for depression, anxiety and RLS. He hasn't been able to get out of bed lately and has missed a lot of work. Could this excessive sleepiness be due to the combination of these drugs? It is not that he doesn't want to get out of bed, it's almost as if he is drugged, which led to my question. This is not normal.
Hi..may I know is there any different type of HCV RNA PCT TEST? Are all the PCR TEST detect the same level of virus? or Cheaper PCR TEST detect slight not as lower as Expensive PCT TEST? Because I found some hugh price differences from lab.
It sounds as if you may have porphryia Cutanea Tarda or PCT for short. This is a skin disease that often goes along with hep C. It is important that you avoid alcohol, stay out of the sun and avoid trauma to your skin. Many of these patients have excess iron. A dermatologist can diagnose this fairly easily.
PCT measurement may add to diagnostic accuracy in patients with systemic autoimmune diseases who present with a febrile illness, especially when highly sensitive PCT assays and specific PCT cutoff ranges are used in a predefined clinical setting (reflecting the likelihood of infection versus an autoimmune disease flare). However, there are limitations when using this biomarker in patients with systemic autoimmune diseases.
I also had PCT cause by hepatitis c. You might need a few more phlebotomies or they might be over. Make sure you get copies of all your test results, I didn't and am nw trying to get them. There is another on this list that knows a lot more than me who had PCT, her name is trinity and I am sure she will be replying to you also. DO NOT DRINK ALCOHOL.
Four years ago I participated in a trail which was Teleprevir Phase ll, which is now know as Incivek. I received all three meds Teleprevir, Riba and Interferon as this trial was not blinded. I was fortunate that my vl was UND in two weeks and was able to do tx for only six months. This was the reason for the trial to see if people could remain UND doing tx for six months. Up until then people had to treat for a year.
I must say those six months were the worst of my life.
My journey began with a dermatologist that diagnosed that I had PCT when I finally went to him about blisters and cuts on the backs of my hands that would not heal ( thought it was a reaction from cleaners that I was using on my boat, but after 6 or 7 months they wouldn't heal properly). From there the journey began and continues. My doc immediately tested for and confirmed HCV. I'm a geno 2 with an very very low VL (initially 470 and now 910 at start of treatment).
You reponded to Kittyface regarding high serum ferritin levels and your explaination was very interesting. I was diagnosed with PCT prior to starting tx in March and had a series of phlebotomies to reduce ferritin level of 783. I was told that high ferritin levels can effect the chances or reaching SVR because the virus uses the iron to replicate and mutate. My bx indicated I had no excessive iron storage.
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