hI, my son now 15 underwent treatment and a bone marrow transplant for Neouroblastoma at the age of four. He's been on growth hormone treatment for 3 years now but with no result. He's only 144cm tall and his endocrinologist says there's no hope because his bones have finished growing and the only suggestion is the bone stretching surgery. Can anyone suggest anything else?
In terms of growth hormone, prematurity and intraventricular hemorrhage are not generally associated with growth hormone deficiency unless there are problems with other hormones also. It is most likely that your granddaughter's small size is due to her former general illness and prematurity. Babies like her need a tremendous amount of nutrition to achieve "catch up" growth, which can sometimes be hard to obtain if she doesn't eat extremely well.
We went to have multiple tests done and they confirmed that im producing next to no growth hormone, or something of that nature. Over the last couple years, I noticed that my friends have been getting taller, while im not. They said that if I dont get hormone injections, my platelets? will close and i wont grow at all. I am considering it and am wondering if there are any severe side effects the medication may have.
m going to have to go through my supplements and meds. The only new med is the Pramipexole .05 twice a day (Mirapex). The supplements are Sam-E, D 2000, A and Magnesium 250 twice a day. I'm going to cut the Pramipexole to once a day. Does anyone see if any one of these would cause this or is there a virus going around?
She is definitely short and body weight is too high for her height, glad to see you saw an endo. She is gh deficient and this is a very good reason for central obesity(more weight around the tummy) and short stature!!! Do not feel overwhelmed, this is good news, she has a chance for treatment, the mri is done on all of my patients before treatment is started, the best websites to go over gh include magicfoundation.
If your daughter is 12, actually the treatments are not really cosmetic. growth hormone while the name says growth, actually has more functions and some are very subtle like sleep and some are more real like muscle growth and bone growth.
The social stigma of being different at this age can also have lasting effects - so if she starts to lose a lot of height and gets behind her peers, she may lose friends. It sounds shallow - but it really hurts and it does happen. It is just that age group.
Has anyone tried Pramipexole (Mirapex, Mirapexin, Sifrol) for chronic pain? I have had low back pain for about 15 years now. I finally got someone to do an MRI back in June (I think, it was slightly before summer 2016) and they found a herniated disc at L4-L5 and a degenerated disc at L5-S1. The neurosurgeon decided surgery wasn't worth the risk and pain treatment was the best option.
Has anyone used a patch? The only med I take is pramipexole.
Those tests are NOT sufficient for growth hormone - those tests are GH (growth hormone) and IGF-1 (which is the derivative hormone that that body actually uses).
TSH is a pituitary hormone but often doctors will say it is normal and it is not. There can be a relationship, but I know more about low GH than elevated GH throwing things off frankly (sorry, I have low GH, not high).
Now, being tall itself is not always a GH issue - it can be just... growth!
My husband is taking clonazepam .05, Lomtrigine 200 mg and pramipexole dihydrochloride 0.25 for depression, anxiety and RLS. He hasn't been able to get out of bed lately and has missed a lot of work. Could this excessive sleepiness be due to the combination of these drugs? It is not that he doesn't want to get out of bed, it's almost as if he is drugged, which led to my question. This is not normal.
He has recently been diagnosed with growth hormone deficiency. His MRI revealed an 8mm pineal cyst and a 5mm pars intermedia cyst interposed between the anterior and posterior pituitary tissue. He also has a lot of fatigue and gets frequent headaches/nausea. He will be starting growth hormone but we've been told that he cannot start the hormones until he sees the neurosurgeon (which is in a couple of weeks). Do you think the cysts may have caused his growth failure?
I heard about gigantism in which people grow upto 8 ft tall, which is because of pituitory gland malfunction, producing too much growth hormone. I recently had Testosterone and thyroid tests done, which came out to be absolutely normal. But no tests were given for Growth Hormone. My concern is if testosterone and thyroid tests suffient to diagnose gigantism?? Is there any relationship between Testosterone, Thyroid and Growth Hormone?? Is my pituitory gland alright? Am I normal?
Growth hormone-producing tumors
These tumors make growth hormone. Too much growth hormone can cause acromegaly (the hands, feet, and face are larger than normal) or gigantism (the whole body grows much larger than normal).
Nonfunctioning pituitary tumors
Nonfunctioning tumors do not produce hormones. Symptoms such as headache or trouble seeing may be caused by the tumor pressing on nearby brain tissue.
The interconnected relationship between IGF1 and growth hormone is referred to as the Growth Hormone/IGF1 Axis.
The growth of the skeletal muscle cells (hypertrophy) is mostly regulated by at least three identified processes,
satellite cell activity
, gene transcription,
protein translation.
IGF1 can influence the 3 above mechanisms.
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