Pioglitazone trials
Common Questions and Answers about Pioglitazone trials
actos
I hope it's not a death sentence! I am a genotype 1a grade 3 stage 3/4. By 26 weeks I still hadn't reached undetectable, so 3 diferent Dr.s in 3 different hospitals said STOP treatment. And I did back in November. I was on weekly doses of procrit too. Well today I am feeling 98% better. I also have NASH. I know this is a silent disease, but worrying about it will not make it better.
Avoiding unnecessary medications can also help slow or reverse the disease. Clinical trials are also looking at the effectiveness of certain antioxidants and newer diabetes medications in treating fatty liver disease. This is because of the disease's link to oxidative stress and diabetes.
Antiviral and antineoplastic activities have also been reported in vitro. Four clinical trials found bitter melon juice, fruit, and dried powder to have a moderate hypoglycemic effect. These studies were small and were not randomized or double-blind, however.
For women who are unresponsive to clomiphene,the oral hypoglycemic agents like metformin could be of little help, or pioglitazone, may bring resumption of regular cycles and ovulation. These agents reduce the hyperinsulinemia and hyperandrogenemia in PCOS.
These are actually medically prescribed medicines for PCOS.As this syndrome is very common in women the case is often individualised and treatment option will be processed and prescribed.Fell free to talk to your Doc.
Whether these substances actually help treat the disease is not known, but the results of clinical trials should become available in the next few years.
Another experimental approach to treating NASH is the use of newer antidiabetic medications—even in persons without diabetes.
t be included in the trial. So to answer your question, there are very strict guidelines relative to clinical trials. As Bill said, go to the website and read some of the trials.
Are there any new trials other than interferon or ribaviron, I've relasp twice and there nothing else my Doc says he can do.
Is the pitting edema progressive? Are you on pioglitazone? or rosiglitazone? Answers to these questions would further help.
I am obese (300lbs), diabetic (type 2) and require medication to control hypetension. I take the following medications – Metformin, Pioglitazone, Victoza (liraglutide), Amlodipine, Ramipril, Bendroflumethiazide, Asprin and Statin.
I have a strange and embareasin problem. I hope someone out there may be able to offer some insight. I have always had sensitive nipples but in the last few days sensitivity in my left nipple has gone crazy.
HI,
It sounds like your wife will definitely need an additional medication--if not restarting the Pioglitazone, then an alternative. There are lots of different diabetes medications available that will help. Those glucose levels are indeed too high and should be addressed soon. Please ask your wife to contact her doctor as soon as possible(I suggest within the next 2 days a most) and discuss being started on another medication to bring her levels down.
Other newer insulin-sensitising medicines include pioglitazone. This is not currently recommended for PCOS. For certain people with PCOS, a specialist may advise that metformin be taken. However, further research is needed to confirm the role of these medicines in the treatment of PCOS.
hi -- a few weeks ago there was a guy who posted here looking for user-friendly clinical trials sites. He was getting medical help outside of the U.S. I can't find his post....so thought I'd write a new one hoping he'll find this. I found this site today and thought of him.
http://www.centerwatch.com/patient/pns/patemail.
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