Pioglitazone fatty liver
Common Questions and Answers about Pioglitazone fatty liver
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Meanwhile, he and his colleagues are investigating the biological mechanisms by which vitamin E or pioglitazone might reverse fatty liver disease. Cusi’s research group is testing pioglitazone against fatty liver in Hispanics, who seem prone to the disease, and in people with diabetes."
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Just got back my results for my ultrasound and my doctor said it came back as a fatty liver. I have been up all night reading about this and it has jusy gotten me stressed and the only thing i read was to change my diet and try to lose weight. I guess that is my next step and i will see how this goes. My doctor didnt even give me too much info thats why im so confused i had no idea where to begin.
These blood tests are within normal range so they tell us nothing about any liver disease you may have. How was NASH diagnosed? A liver biopsy? By ultrasound, CT or MRI where the fatty deposits in your liver where seen?
If you have been diagnosed with NASH (NonAlcoholic SteatoHepatitis) you should be being seen by either a gastroenterologist who is experienced with managing NASH or a hepatologist (liver specialist) at a liver transplant center near you.
These findings suggest that chronic administration of TZD has anticancer activity in the liver via inhibition of NPM expression and indicate that these drugs might be useful for HCC chemoprevention and treatment. HEPATOLOGY 2010.
http://en.wikipedia.org/wiki/Thiazolidinedione
this drug is same family as Rosiglitazone (Avandia) which has been foud active on hbsag and hbvdna, question is does TZD lower hbsag since decrease of hbsag inibits cancer growth too and if lowered to und eradicate hbv?
I've been in active HB fro 6years and I found out I have 0.8mm lesion on my liver 5 years agao.
I got CT scan and doc said, it is normal one. 4years ago, I met new doc and he also found out it from Ultrasound test and recommand to have MRI and I did, still it turned out as normal. every six month I had UT test and it been in normal. but last UT test, it increase 0.8mm to 1.2mm.......
My doc want to have MRI again and I'm waiting for it I'm really scare....
There have been a few cases of liver failure possibly related to the use of mesalamine (the active ingredient in Asacol HD), but I haven't read anything about fatty liver as a side effect.
A fatty liver, it takes between 6 months and 2 years to fully reverse. Dr Sandra Cabot's article "Fatty Liver - What Is Fatty Liver And How To Reverse It?
You have to get yourself properly evaluated for the fatty liver changes. Fatty liver can be due to alcoholism when it is called Alcoholic fatty liver disease and the other one is Non alcoholic fatty liver disease, which is due to obesity, diabetes and high triglyceride levels. This can progress to cirrhosis of the liver and can be associated with hepatocellular carcinoma. So, prevention or cure is by avoiding alcohol and treating diabetes, obesity and high triglyceride levels.
I recently had an ultrasond-7/2014- and the findings were - Mild increase in heoatic echotexture. Can be seen in early hepatic steatosis.(Fatty Liver) GI says he doesn't think I have fatty liver.He thoght it was just inflammation. I am 5'1" height, 120 lbs. Don't drink alcohol, soda, etc. However I did consume quite a bit of fruit - mostly apples, oranges,bananas. I have cut way back since - no bananas at all. Had CT scan 5/2012 liver appeared fine.
I was diagnosed with a nonalcoholic fatty liver and had a biopsy and it is 50% fat. I could not take statins and my cholesterol, trig, etc. was sky high. I finally got a doctor who found a statin that I could take without all the side effects and my numbers are going down but it's only been two months that I have been on this.
But other foods and sugary drinks can cause steatosis (fat) development in the liver. Fortunately though, fatty liver disease can be reversed and even eliminated relatively quickly, when compared to the other etiologies of liver disease.
By focusing on fresh, unprocessed foods as the main portions of his new, healthy diet, he can start on making his liver as good as new. Lots of fresh vegetables and fruits with minimal amounts of vegetable or animal fats - olive oil is good.
Keep in mind that fatty liver is very easy to improve, but it will take disipline. You need to work with your doctor and try to improve your diet and add exercise as well. In fact, fatty livers can be resolved in just several months, n some cases. But you do need to make changes. Your numbers aren't alarming but they are a warning. Take care.
Then i had a ultrasound and CT scan and the doc said that i have an enlarged fatty liver and sterosis or something like that. What causes this? I dont drink alcohol at all or smoke or use drugs. The doc didnt give me any medication or tell me any advice or anything he just reffered me to a specialist and in have to wait months before he sees me. Can anyone offer me some advice on diet or what the problem could be?I feel its getting worse and i dont even have a proper diagnosis yet.
Triglycerides (TG) are actually the fats which get deposited in the liver causing fatty streaks within the organ. Any fatty liver condition is associated with impaired fat breakdown. TGs are broken down and stored within the liver. When circulating levels of TGs surpass the livers ability to break them down they are just enter storage instead. This makes it easy to understand how chronic high TG levels can lead to a fatty liver.
Liver problems including hepatitis are easily detected by an ultrasound scan and liver enzymes (which are raised). Hepatitis can result in fatty liver, but usually fatty liver is associated with fat rich diet, drinking alcohol, diabetes, obesity and dyslipidemias (high cholesterol and triglycerides). The good thing is that it responds to diet control and exercise. Also, yes, inflammatory bowel disease (which also causes lot of gas and stool problems) can also cause fatty liver.
From the report there is evidence of fatty liver changes in the liver. Also, it shows inflammation of the liver with some fibrosis. This is graded to determine the progression of liver disease. The report indicates an ongoing inflammatory change in the liver. The galls stone is unlikely to have produced these changes in the liver. It could be due to alcohol. And stopping alcohol would be the first step to prevent any further damage to the liver.
Hope this helped and do keep us posted.
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