As a result, some people risk skin infection and injury by scratching
themselves with sharp objects. Certain drugs can help reduce
itching, particularly classical analgesics
for neuropathic pain (gabapentin,
antidepressants) which also exhibit antipruritic efficacy upon clinical use. Some people find that antihistamines, such as diphenhydramine (Benadryl)
or hydroxyzine (Atarax), help relieve symptoms and allow better sleep.