Never took
Nexium or any PPI prior to treatment, but took
Nexium a day for most of treatment. After treatment, I was able to stop completely. So, treat yourself a little more of that purple pill if it will make your QOL on tx better. In addition, you might also try an H-2 pump like Zantac or Pepsid AC (not Pepsid Complete) at bedtime. Also, an antacid (like Tums, Mylanta) here or there is no problem as long as you space it around 3 hours away from your riba dosing.