There are no factors, including duration of therapy, that are known to predict the risk of occurrence or the severity of rash associated with
modafinil or NUVIGIL. In cases
where the time
to onset was reported, serious rash occurred 1 day
to 2 months after initiation of treatment, but isolated cases of serious dermatologic reactions have been reported with symptoms beginning after prolonged treatment (e.g., 3 months).