There have been a few cases of liver failure possibly related to the use of mesalamine (the active ingredient in Asacol HD), but I haven't read anything about fatty liver as a side effect.
A fatty liver, it takes between 6 months and 2 years to fully reverse. Dr Sandra Cabot's article "Fatty Liver - What Is Fatty Liver And How To Reverse It?
During moderate/sever flare-ups I took prednisone orally, in foam suppository as well as mesalamine orally and through suppository. In moderate flare-ups mesalamine orally w/ mesalamine suppositories.
My question is - beyond the general risk that HSV presents - how additionally risky is this for me? It is a possibility that at some point I will have a flare-up that will require immonusuppressive therapy. If I was to contract HSV could my UC symptoms become more severe?
The cyclosporine I was taking was a powder in a capsule, apparently this has been taken off the market and instead I took the same medication, but it was in the form of a capsule with alcohol. Unfortunately, after a short time, I was right back to before treatment. And have been avoiding culprit foods ever since. I contacted my doctor and his guess was that the powder worked topically in the digestive system and the alcohol is metabolized by the liver and therefore does not work as well.
Her gastroenterologist started her on Mesalamine (4 capsules daily) and later added prednisone 100 mg enemas to try and get the flare-up under control. Things are getting better and she has some of her strength back. There is one puzzling thing that the doctors are not able to pinpoint. This is an intermittent fever that starts in the afternoon and lasts to the night. In the morning the temperature is back to a low 97 degrees fahrenheit and stays stable until afternoon below 98 degrees.
In March 2009 I was diagnosed with Eosinophilia (40%), Hypogammaglobulinemia low IgG (407) after going to the doctor with stomach pain and alcohol intolerance (0.5 ounce of wine or whiskey would trigger a violent attack within minutes, while grape juice does not cause an attack). Asthma (85% lung capacity), lung granulomas, lung nodules and possible mild Bronchiectasis.
My recent result of biopsy after the colonoscopy indicates epithelial dysplasia. My doctor just advice me to continue taking the mesalamine (Asacol) Do i need an another urgent medication/treatment for dysplasia? What should be my next move?
I have read about a study in which Boswellia was used in conjunction with Mesalamine. My gastroenterologist knows notheing about herbs, but is open to information that I can give her. What is available? Are there any interactions with boswellia and mesalamine that I should be cautious about? Are there any precastions about its use?
Hi there,
I was diagnosed with sigmoidal colitis in 2005, but I reckon that it went unchecked for about 4 years prior to that. I was initially treated with mesalamine (Asacol) but it had no effect. My GI guy then hit me with prednisone and that knocked it down. I have been on Asacol in a prophylactic capacity since (800mg tid). Does it keep me in remission. Maybe, but maybe it is the tremendous quantities of fentanyl, diacetylmorphine and morphine I abused as well for all I know :P.
What other symptoms are present? Mesalamine or Canasa suppositories works by preventing the production of substances that cause the inflammation of the colon. The usual side effects include diarrhea; dizziness; gas; hair loss; headache; mild stomach discomfort or pain; and nausea. The sour taste could be indirectly related especially if you have other gastrointestinal issues like acid peptic disease or gerd.
She again had colonoscopy and histological examination inferred that it was ulcer. She is being treated with Mesalamine and now she is well. Please check with your doctor.
The periods of remission can last from weeks to years."
***
Springer - Mimics of Ulcerative Colitis...
"Infectious colitides such as Clostridia difficile, hemorrhagic E. coli, Campylobacter, Aeromonas, and Salmonellosis can often present as severe ulcerative colitis. Other infectious pathogens, which also need to be included in the differential diagnoses, include Amebiasis, Shigellosis, Cytomegalovirus, and Rotavirus.
I have Crohn's also. I'm pregnant with my second child and have not had a problem either time. However, my doctors did tell me that if you're Crohn's is under control when you get pregnant, it's likely that your condition will stay the same or get better during pregnancy. If you're having a flare up or the disease is not controlled well when you get pregnant it will likely get worse.
In terms of medication I would trust your doctors here.
If it is not effective, then other medications like steroids, mesalamine and bismuth subsalicylate may be tried.
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The information provided is for patients’ education only and is not a medical advice. Always consult your personal physician for complete evaluation of your health problem.
- Ratnakar Kini M.D.
Hi, I am 23 years old and am currently in a flare up that started back in November 2009. I have tried Mesalamine, Prednisone, 6MP, Remicade, and am currently taking Humira and Methotrexate once a week. I feel like my life has been taken away from me. I was studying abroad for a master's degree when the flare up set in and decided to fly home to my parents to get proper health care and support.
Hi Nicky.
I'm sorry about your recent U.C. diagnosis.
According to the mfg:
"The dosage of Mesalamine 500 mg suppositories (Generic Canasa) is one rectal suppository once daily at bedtime.
The suppository should remain inserted for one to three hours or longer, if possible. The normal course of therapy is from three to six weeks depending on symptoms and sigmoidoscopic findings".
So the 30 day supply falls within the recommended duration.
07-2007 - to help fight off inflammation. I've read that prescription drugs were often safe, way beyond the expiration date. Don't have much of it left though.
So without going through the 'hassle' of getting an appointment, trying to get treatment, etc. is there something I can do on my own?
Thank you.
the doctor at the time told me that it was the same thing as asacol, however, i found it to be less effective. another doctor later told me that they have the same active ingredient mesalamine, but pentasa reaches a different part of your track... i think asacol stays intact longer, so it gets released lower down in your system.
anyway, i think either of the 2 drugs are mainly for maintenance like the others said.
Ive not tried the red one, but the white non-alcohol wine tasted oddly of white grape juice and pop rocks lol.
Alcohol can make someone get behind the wheel of a car and go out and kill innocent people. I don't need alcohol and drugs to make my life unmanageable. Alcohol is only a symptom of my disease of addiction. I need to treat the entire disease.
I REALLY like the message OpenMind24hours gave You.
I agree with Her description of an "allergy to alcohol" but I would take that a step further and say the reason We are "allergic" to alcohol is because alcohol is a poison to our bodies. EVERYONE who drinks enough to get drunk will have Their body react - Our bodies are sending us a 'message' - "this is not good for my ENTIRE system".....
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