Eithne01,
The treatment of chronic myeloid leukemia (CML) has changed significantly since the late 1990s, with the development and subsequent approval by the Food and Drug Administration of imatinib (in 2001), the first of a class of medications called tyrosine kinase inhibitors, which target the specific abnormality that causes CML.
Before that time, patients were treated with other therapy, including interferon and bone marrow transplant, and had very poor outcomes.
Are you currently on any medication like imatinib? The neutropenia can be due to your current medication. You can ask your hematologist for G-CSF injection if you have persistent neutropenia. Patients with CML are immunocompromised and can easily acquire infections. Neutropenia also puts a patient in an immunocompromised state.
For now, it is very important to prevent acquiring any infection. You should avoid crowded places and persons with ongoing infection.
Good luck.
Hi.
Chronic Myelogenous Leukemia (CML) is a blood disorder caused by an acquired genetic defect in the pleripotent stem cell. It has several phases: indolent chronic or stable phase, aggressive or advanced phase, and accelerated and blastic phase. The transition between phases may take years (on the average, 4 to 6 years from the stable phase to aggressive phase).
Hi. Where was your melanoma located? Was it near your nose? I checked the official prescribing information for Veramyst (fluticasone nasal spray) and it does not specifically state that this drug is contraindicated for those with melanoma or any other cancer. However, for those with recent nasal surgery, this drug should be avoided as it delays wound healing and increases the risk of fungal (Candida) infection.
Average survival rates are generalizations, not applicable to a particular patient. The prognosis is relatively good. Newer techniques are being tried, including imatinib and stem cell transplantation.
All the best, and God Bless!
Now I am terrified that it was a melanoma and I have scrapped it off and the cancer will start growing without me knowing. Can you scrap off a melanoma? If it was a melanoma will the pigmentation grow to the surface again? Does melanoma heal? I know if I go to the gp they will not refer me to a dermatologist and can not afford to pay privately.
It is unrelated. Where is the melanoma in the eye? What type of surgery is planned?
Dr. O.
Hello, I had a suspicious mole on my neck removed in June and it came back as mild-moderate dysplastic nevus with differential diagnosis of early melanoma in-situ. The area was re-excised with 3mm margins. Since then I have had the slides re-evaluated by UPenn Dermatopathology and their diagnosis was Severe dysplastic nevus with differential diagnosis of evolving melanoma in-situ.
I experience no signs (no night sweats, headaches, itching, etc) or symptoms of a recurrent Melanoma or even a secondary Melanoma. I have been looked over by 4 separate Dermatologists every 3 months for the last year and a half. I even had my Melanoma scar biopsied again for recurrence (negative).
My Oncologist is pushing me to get a PET scan done. Now, I'm all for having a PET scan done if there is a high risk of cancer. All the tests I have had done have been extremely positive though.
m thinking about this now because I know I have two lectures tomorrow morning on melanoma that will include more statistics about melanoma including statistics about the current not so great survival rates. I guess I feel like skipping class would be bratty or wimpy when right now I'm perfectly healthy, but I don't love the idea of sitting and hearing about it in that light.
t seem to me to be the usual appearance of melanoma (follow this link to see what the usual melanoma lesions look like: http://www.skincarephysicians.com/SkinCancerNet/melanoma.html). Having said this, I would like to emphasize that the diagnosis of melanoma cannot be made based on appearance alone. A biopsy of the lesion is needed to confirm the diagnosis.
I just wanted to ask if it is possible to spreak skin cancer (especially melanoma) into the body by scratching an infected area until it bleeds. I was told that skin cancer cells can enter the body through the blood stream in this case and then infect other parts of the body, namely, internal organs. Is this true?
Thanks a lot!
Sincerely,
George DeKornfeld
This discussion is related to <a href='/posts/show/242515'>SMALL RAISED RED BUMP ON HAND</a>.
Yesterday my wife was diagnosed with Melanoma via a pathology test and then with a consultation with a skin cancer specialist Dr Robyn Saw. Apparently it is 4mm deep, is this whats referred to as a grade 4 Melanoma?
The doctor is suggesting removal of it from the shin on her leg with a 5cm skin graft and also selective lymph node dissection.
Obviously we are both very worried about it and now have to wait just over a week before surgery on the 27th.
Hello,
Salient feature of subungual melanoma (melanoma under nail) is categorized according to ABCDEF. In this system A stands for age (peak incidence being in the 5th to 7th decades of life and African Americans, Asians, and native Americans in whom subungual melanoma accounts for up to one third of all melanoma cases. B stands for brown to black b and with breadth of 3 mm or more and variegated borders.
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