Humira for uveitis
Common Questions and Answers about Humira for uveitis
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My BD has been maintained by Humira 40Mg weekly and Imuran 200Mg daily for over a year. Prior to that Humira was bi-weekly for about 8 months and Enbrel was used for about 8 months prior to it. All in combination with Imuran 150Mg or 200Mg. During this time I have had uveitis (lasted for about 4 months) followed by gastritis (8 months), followed by strep throat leading to chronic tonsilitis and re-occuring bronchitis flares for 6 months that triggered asthma and now back to uveitis...
I've been undergoing the MS diagnostic process for about 3 years. I used to take a drug for psoriatic arthritis that can induce MS or MS-like symptoms in rare cases. I had tingling and numbness on the left side of my face, extending down through my left arm. I also had burning sensations in my fingertips, and buzzing in my fingertips, along with recurrent uveitis. I was MRIed twice. The first time I had 1 lesion, and the second (one month later) there were 3 more lesions.
You should have had a complete medical work-up to determine what is the cause of your uveitis (likely you have some underlying systemic disease) and you should probably be on oral medication for uveitis monitored by the rheumatologist. Have you had that done? Where do you live? Chronic use of pred forte besides causing cataracts and often glaucoma can make the eyelid droop (called ptosis).
Having started the TB medication for a week we now wish to continue her treatment for UVEITIS . As I came to know that Steroid is the only option for treating Uveitis I am afraid of both (TB and Uveitis) the medicines that will add extra weights in her body. Any solution to that? Or any expert comment to help me.
I used to take a drug for psoriatic arthritis, humira, that can induce MS or MS-like symptoms in rare cases. 3 years ago I had a 6-month bout of uveitis. The doctors couldn't figure out what the underlying problem was, so they ran me through a MRI. They found 1 possible MS lesion or UBO. Then a month later, I had tingling and numbness on the left side of my face, extending down through my left arm. I also had burning sensations in my fingertips, and buzzing in my fingertips.
Like heart disease, uveitis ranges from a single episode that is easily controled and never comes back to relentless progression to blindness. And everything in between. The treatment of uveitis has improved dramatically in the last 2 decades. All the patient's with uveitis that I've managed have done well with IOL surgery.
Anyone having cataract surgery should not expect perfect vision because other parts of the eye are usually affected by disease or age.
Hi
I hope to get some info and help
I have Crohn’s Disease and Ankylosing spondylitis for over ten 15 years now and have taken steroids and Mezavant XL 4800mg which always have worked, but have caused a cataract. I am now on Mezavant XL 4800mg and weekly Humira injections for 6 month. At first Humira worked completely, but for the last 3 month I now have got again explosive Diarrhoea and bleeding.
Anyone taking humira and feel like they are sick coming down with a cold for a week after injection? Not a full blown cold but the start of one. I feel like this always and this is my 3rd dosage ( counting the starter kit), so I'm new to humira. I've noticed if I'm stressed, I'll even get a sore throat. I know humira suppresses your immune system but are you supposed to feel like you're coming down with something every injection or will this go away with time?
I hve hsv1&2 for over 6 yrs nw ,no flare up for two yrs.I just started humira then out the blue I flared up,nw I'm due for my 15th day injection but hve to wait for my Doc to call to let me know if I'm able to continue the humira injection wth this active virus.I think the humira reactivated the virus,wow! What u suspect she'll say?
Hi monicaroni, I have been taking Humira almost 8 months. I take humira for Crohns Althougth reap the benefit for the AS. I am thinking that you probably had a concurrent infection brewing when you Started Humira. Good Luck managing your AS, I appreciate how difficult it can be with mobility issues, and treating pain.
actually be experienced by pwMS, if it is caused specifically by MS is difficult to pin down, the uveitis stats are quite small when they are looking at a possible connection for uveitis as a sx of MS.
To explain what i'm trying to say, one example of the disparity would be the larger number of dx uveitis patients in a study and the MSers are commonly in the minoriety eg 1267 uveitis patents and only 41 dx MSers. Which is just over a 3% sample base and means the other 96.
Thank you so much for your response. I was told that both uveitis and shingles can be brought on by stress in the body. I was hoping that if there were diseases that could cause both I might be able to narrow the list as I don't seem to be getting a lot of assistance on this end. I will definitely look for a uveitis specialist - thank you!!
As you well know Humira is an immuno-suppressive
drug , which mainly inhibits TNF (tumor necrosis factor).
There's a growing amount of evidence of the development of Autoimmune conditions, related to TNF inhibitors, such as Remicade, Humira and other biologics.
I've had uveitis for three years, treated with cortisone drops, pred forte drops, dilating drops and a cortisone shot in left eye. Lost most of vision in that eye because optic nerve was mostly destroyed.
I did research on websites, and saw that uveitis is an auto immune disease and saw a rheumatologist who prescribed Methotrexate. Uveitis went into remission immediately, and I haven't had a recurrence in 2 years!
My wife has been on Humira for about 4-5 months and it hasn't helped! she just had a blood test and her inflammation is very high. her Gastro. Dr. wants to see her in another month and take another blood test. Have you an opinion on the drug Naltrexone and vedolizumab.
Remicade is a biologic injection, in the same class of drugs as Humira, Enbrel and Orencia. I have been taking Humira for rhematoid arthritis and it seems to be doing it's job as my rheumy says. It keeps me out of the emergency room with serious flares which had become a habit for me.
These drugs are usually reserved for "rheumatoid" type arthritis and getting insurance companies to approve them is not normally easy.
Based on retrospective studies with cohorts of n ≥ 1,000 patients, we estimate that the prevalence of MS among patients with uveitis is ∼1%, and the prevalence of uveitis among patients with MS is ∼1%, which in both cases is considerably higher than in the general population according to studies on prevalence in western countries.
Results from larger studies are to be assumed as the closest to a true estimate.
I have been on Humira for psoriasis for approx. 9 mos. now. In the beginning I noticed that I as well had some swelling. I got reading alot about reactions etc. It did say that your body does contain more water which in turn would cause swelling. I myself found that after about 3mos. I had gained weight, not that I couldn't afford to but all the same I did find it a little odd. After reading so much on Humira, I dont' think I've missed a page, it is one of those side effects.
I've been on Humira for about 6 months and I have been messing with my injection times a lot over the past couple months. Humira is the only thing that keeps me going, but I have to do it weekly.
I noticed when I missed my dose, when I was doing it bimonthly, my symptoms would just keep getting worse.
We did a few psychological tests to see if my symptoms were coming back due to an emotional connection. That was quickly proven otherwise as I started to vomit and have bloody stool.
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