How often should an endo be checking to see if you need less calcium and how do they know when to take you off calcitriol? If you are on calcitriol, how can they tell if your pth is coming back normally? My endo looked at these numbers and said continue on the high dose of tums and the calcitriol and come back in 2 months!!!!! I am scared I will be on the large number of tums forever and taking Rocaltrol forever.
parathyroid failure after 3 years post TT?
by LLV123, 4 minutes ago
Hi, I had TT 3 years ago, had 1 para removed accidentally, 1 re implanted, 2 were "fine" Had low Ca post TT for a few weeks, then ok. Now, 3 years later, had some muscle twitching, had low ionized Ca {1.09, 1.10, 1.14 after I had infusions for 3 days of IV CA. Serum was ok, not high but low 8's. My endo put me on Calcitriol and said para's are failing. NO WAY!!
Vitamin D blocks the growth of cancer tumors. The active form of vitamin D, calcitriol, does most of the work. Calcitriol is made in the liver and in various organs affected by cancer. This form of vitamin D offers several benefits:
* Activates vitamin D receptors, which turn genes on and off
* Prevents cancer from starting (Calcitriol encourages cells to either adapt to their new organ or commit apoptosis [cell suicide].
I have been on a regime of Synthroid, Cytomel (T3) and Calcitriol for 18 months.
Blood assays have been in the correct range for the past 14 months.
No recurrence of any tumors
During the past six months I have been experiencing high blood pressure and two TIA's (mini strokes).
Is it possible that my supplement program could be elevating my blood pressure?
Treatment with vitamin-D(3) resulted in calcitriol production and induction of calcitriol target gene CYP24A1, indicating that these cells contain the full machinery for vitamin-D metabolism and activity. Notably, treatment with calcitriol resulted in HCV inhibition. Collectively, these findings suggest that vitamin-D(3) has an anti-viral activity which is mediated by its active metabolite.
If parathyroids don't "work", typically, they are removed, in order to prevent problems. Possibly, one or both of them "does" work, at least, intermittently in order to raise your levels that high? This does seem to be a parthyroid issue.
Since then, have been hypocalcemic and taking multiple daily doses of calcium and Calcitriol (1500 mg calcium, 3xdaily). Both endo and surgeon say it can take up to a year for normal calcium production to resume. I had RAI (200 mCi) Feb. 29 and started on Synthroid March 3. Trying to fit all of the calcium doses around the Synthroid (no calcium 4 hours before/after Synthroid) is problematic.
We brought her in for dental work and the blood tests showed high creatinine and urea. Her phosperus levels are normal with elevated calcium.
She is showing no signs of sickness. Her appetite is great, lots of energy, etc. 4 years ago another blood test showed the same calcium levels but normal kidney function. My vet(s) are confused by the test results. All her other blood tests are normal (sodium, pot, protein, etc)
We are giving her subcutaneous fluids, a kidney diet and some probiotics.
I am taking calcium supplements and vitamin d, but just learned that I need to be taking activated vitamin d, (Calcitriol). The problem is that Calcitriol gives me horrible stomach pains. Does anyone know of any other activated vitamin d I could use?
More importantly, has anyone out there had their parathyroid function resume/completely recover after months of low parathyroid function? It's been over 5 months since my surgery, and they still haven't kicked in.
Once the sum of the blood calcium multiplied by the blood phosphorus levels are less than 40, then that dog (or cat) is a candidate for a natural product called Calcitriol. Calcitriol is a natural form of Vitamin D that was formerly used for human dialysis patients to restore kidney function. Calcitriol is currently available for dogs and cats in kidney failure and veterinarians order it through various compounding pharmacies.
These cells express CYP27B1, the gene encoding for the enzyme responsible for the synthesis of the vitamin-D hormonally active metabolite, calcitriol. Treatment with vitamin-D(3) resulted in calcitriol production and induction of calcitriol target gene CYP24A1, indicating that these cells contain the full machinery for vitamin-D metabolism and activity. Notably, treatment with calcitriol resulted in HCV inhibition.
These cells express CYP27B1, the gene encoding for the enzyme responsible for the synthesis of the vitamin-D hormonally active metabolite, calcitriol. Treatment with vitamin-D(3) resulted in calcitriol production and induction of calcitriol target gene CYP24A1, indicating that these cells contain the full machinery for vitamin-D metabolism and activity. Notably, treatment with calcitriol resulted in HCV inhibition.
Hi, I had TT 3 years ago, had 1 para removed accidentally, 1 re implanted, 2 were "fine" Had low Ca post TT for a few months, then ok. 3 years later, had low ionized Ca had infusions for 3 days of IV CA. Serum was ok, not high but low 8's. My endo put me on Calcitriol and said para's are failing. NO WAY!! I showed blood work "pre" TT and Ca was 8.4 so run lowish. Took Calcitriol for 3 days, asked endo if I could try OTC to raise it, didn't like the Calciriol...
They are suppose to strip my membranes how does that work? Does it hurt.
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