Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great.
I hope this helps you. I would be glad to help you with any other questions.
i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
In their report, the researchers also discuss the compassionate use of Gleevec in one young neurofibromatosis patient with an airway-compressing plexiform neurofibroma. This patient was not considered an ideal candidate for surgery given the location of the tumor and its vascular nature. A three month administration of the drug was effective in significantly shrinking the tumor without any observed side effects.
I recently asked a quesrion regarding a patient with a small rectal cancer that could have been treated with radiation, but the radiologist consulted with does not recommend radiation as the patient had a cobalt implant 40 years ago for cervical cancer & thinks she has had too much radiation. She is 79 years old & NEEDS TO KNOW if there is another way to treat it without surgery requiring a colostomy.
After body has immuno response, such as produce antibody and huge amount of hiv specific killer T-cells, CD4 will have slightly increase, but CD8 has more significantly increase. Positive patient has CD4/CD8 ratio <1.
Skull osteomyelitis presents with headache as the initial symptom and then as the areas of brain and cranial nerves supplying that area become involved,patient may present with variable symptoms depending on the same.
If you are having any such symptoms,then I would advise you to consult an orthopedician and get MRI of the area along with gallium bone scans.biopsy of the bone may be required to confirm the diagnosis.
I sincerely hope that helps. Take care and keep me posted Kind Regards.
Thanks, appreciate the information.
Hi!
If you were my patient, I would advise you that maybe the oral contraceptive is not the best option for you. There are patches and vaginal inserts that might work better because they bypass your stomach. There are also injectable and implantable contraceptives that are very convenient to use.
Starting and stopping birth control can cause irregular bleeding, so that is not too unusual. I always recommend a pregnancy test too though, whenever the bleeding is different that expected.
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