Recently, she has been in and out of hospital for critically low sodium level. This has occurred for about a year. Anyone experienced similar problems or know of any research showing causal link?
Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great.
I hope this helps you. I would be glad to help you with any other questions.
i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
* buprenorphine Metabolized into norbuprenorphine by cytochrome-P450 isoenzyme 3A4
* Tyrosine kinase inhibitors, including Gleevec and Tasigna, used to treat chronic myelogenous leukemia and gastrointestinal tumors.
There is no genetic basis for the CML therefore she was not put on Gleevec. She is on Hydrea to keep the wbc count down to a more normal level. I think the only thing that led to the CML diagnosis was the extremely high wbc with no sign of infection or other cancer. Mayo did the same blood tests as the hometown doctor, as well as the lab in Iowa City. I would like them to run other tests but havent a clue what to ask for.
Your TSH level is at the lower level of normal; I'm sure your doctor is perfectly happy with it... however, I have to ask if that's all that was tested? Did your doctor not order Free T3 or Free T4 to go along with that?
Free T3 and Free T4 are the actual thyroid hormones, while TSH is only a pituitary hormone and should not be used alone to diagnose or rule out a thyroid problem...
Do you have any symptoms of a thyroid condition? If so, what are they?
Hi there and welcome. Honestly I don't know a lot about CMML but from what I can gather online, it sounds like a monocyte level over 1000 indicates CMML. Obviously you already have had CMML, so I'm not certain what the level would have to be to indicate treatment for a reoccurance. Has your doctor told you when treatment will be neccessary?
I have just seen a doctor about the results of a bloiod test taken for my thyroid levels and it was very alarming. She said normal range was between 1 and 4 and mine was 151! SHe used the word critical . Could the results been a mistake? I have been on synthroid in the past but stopped abruptly for about a month and have had many other health issues . I am very tired and can't sleep because of severe hot flashes and I've gained a tremendous amount of weight.
Sorry, something went wrong in my previous comment.
afaik the normal value for Troponin I is :
normal range <0,10µg/L (some say 0,50µg/L
So, according to this you are measured high in the intermediate range.
Is further testing planned for you?
My boyfriend (40-years old) has dealt with a number of health issues (leukemia, crohn's, 1 previous episode of ischemic colitis)
Although he finished his last round of chemo a couple of months ago and appears to be cancer free at this point, his oncologist said he would not feel perfect for awhile.
About a year ago, he saw a doctor for an upper resp infection. After three days in heart hospital the findings were super ventricular ectopy with sinus bradycardia.
For instance the treadmill can measure in METs (metabolic equivalent tasks) the energy expended at a given level of exertion. At a given MET level, vital signs are monitored, heart rate, respiration, etc. For a perspective 1 MET is the amount of energy to quietly sit, 2-4 METs to walk up a flight of stairs ( 7 METs usually qualifies for surgery. Ten METs is very good condition, etc.
No need to be scared.
Does anyone know what a normal hcg level is? Just got my pregnancy blood work back and it was positive, but the doctor said my hcg level was 195. This makes me a little nervouse because I thought that you usually started with a number below 100, does this mean something went wrong with the IVF?
I agree, you must get back in touch with your doctor in order to go over the test and possible further testing. A high AST level is an indication of organ damamge, so it is very important to take this up with someone who has all of your medical history at their fingertips.
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