Hi Jose,
I did a little research on the Gleevec website and here's what it said:
"Patients should avoid grapefruit juice and other foods that may affect how GLEEVEC works." I'm not sure what it means by "other foods".
I've also heard that foods high in antioxidants (such as pomegranites, berries and some beans) can actually work against some cancer drugs, but I'm not sure about Gleevec. It's probably best to consult your doctor.
* Anthelmintics (Used for treating certain parasitic infections, includes praziquantel albendazole and mebendazole)
* carbamazepine (Tegretol) Grapefruit or grapefruit juice slows the breakdown of this drug, increasing the level of it in blood
* Loperamide (Imodium), the anti-diarrhea drug
* colchicine (Colcrys)
The CYP3A4 isoform of cytochrome P450 is located in both the liver and the enterocytes. Many oral drugs undergo first-pass (presystemic) metabolism by the enzyme.
Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Is it possible that after taking gleevec for only two weeks WBC droped from 36.7 to 7? All other blood counts are also came back to normal range. Could doctor make mistake in diagnosis of CML? Maybe I should get seg second opinion?
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
After two weeks on 400mlg gleevec my WBC droped from 36.5 to 7.1. My doctor told to come for additional test in two weeks. Now my WBC is 1.3 and absolute neutrophils count is 0.04. I was told to stay home on antibiotics. How long it may take for my counts to clime back to safe range. And of course, I'm off gleevec right now. Does it seem that dose of 400mlg is too high for me.
Am on Gleevec 400mg, now having problems with blisters on the palm. What can I do about it?
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great.
I hope this helps you. I would be glad to help you with any other questions.
Is grapefruit OK to eat for breakfast everyday? I tried to Google but no good answers. I know it is acidic, but I don't think harmful. Just want to make sure.
i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
//en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_interactions
I avoid grapefruit because it interacts with simvastatin and oxycodone. If you are taking other medications please check with the respective provider and the pharmacist about interaction with grapefruit.
A Potential for Adverse Events
Many patients may take their medications with a glass of juice. However, since the accidental discovery of an interaction between the calcium channel blocker, felodipine, with grapefruit juice,1 it has now become evident that grapefruit juice has the potential to alter the plasma concentrations of many medications when they are taken by mouth. In some cases, this may result in undesirable clinical effects of medications.
Hi I did a search and found this, it appears it is just the grapefruit juice. My Mom was told not to eat grapefruit with her Synthroid. I think it can increase that dose as well.
http://www.livestrong.
Do you mean with olysio, grapefruit not allowed ?
I decided I was going to lose weight and eat healthy this year so about a 11/2 week ago someone told me that grapefruit helped with weight loss. I started drinking 2 8oz (I think) cans of juice a day for 7 days and I was adding grapefruit essential oil drops to my water. I didn't really feel different I was sweating more but I thought it was from the grapefruit working and I wasn't sleeping hardly at all.
The report is specific to only eating Grapefruit or drinking Grapefruit juice. There is no mention of any other citric juices, including Crystal Light. Below is the information that you may have already seen but I thought you might be interested.
While you are taking this medicine, you should avoid eating grapefruit or drinking grapefruit juice. You may choose an alternative citrus beverage (such as orange juice). In the event that you are instructed by a healthcare professional (e.g.
I remembered something about not eating grapefruit because it can reduce absorption of the Riba. I googled, but only found one article... seemed to indicate this is so.
Does anyone know if this is a fact? I love citrus.... and I just bought a nice fresh bag last time I went shopping. Should I toss the grapefruit in the garbage?
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