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Gleevec and grapefruit

Common Questions and Answers about Gleevec and grapefruit

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Avatar n tn Hi Jose, I did a little research on the Gleevec website and here's what it said: "Patients should avoid grapefruit juice and other foods that may affect how GLEEVEC works." I'm not sure what it means by "other foods". I've also heard that foods high in antioxidants (such as pomegranites, berries and some beans) can actually work against some cancer drugs, but I'm not sure about Gleevec. It's probably best to consult your doctor.
Avatar m tn Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count. This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Avatar n tn I was diagnosed with CML in May with WBC at 222 and an enlarged spleen. Currently on Gleevec 400mg and the last FBC shows WBC at 2.1 . Still maintaining current dose of 400mg.Apart from some annoying blisters on my palm, other side effects rather acceptable.
Avatar n tn I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
Avatar n tn t want to see me, that fever was not from gleevec, and that I needed to monitor myself by myself by simply taken ibuprofen. This is what I did all last week and only this Monday he did a blood work. For now, what can I do to help my body to build my immune system back? Any vitamins? I'll appriciate any advice.
Avatar f tn I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
Avatar m tn I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
268911 tn?1213744781 Grapefruit and grapefruit juice may interact with Xanax and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.
Avatar m tn My wife has been perscribed fentanyl patches and has been told not to eat grapefruit, does this apply to all citrus fruit ie.
Avatar m tn http://www.medhelp.org/posts/Hepatitis-C/Treatment-for-Hep-C--Grapefruit-Juice/show/542498 “It actually can increase some drug levels because of inhibiting a liver metabolic enyzme. However neither interferon or ribavirin is metabolized by that particular enzyme(p450) so it is OK to drink your grapefruit juice. Stay Healthy!
689327 tn?1240229164 grapefruit makes your body metabolize the medicine faster and could result in overdose.
Avatar n tn You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great. I hope this helps you. I would be glad to help you with any other questions.
Avatar f tn Several of my drugs (Lamictal, Seroquel, & Valium - at a minimum) interact w/ grapefruit. It's on all of the information that comes from the pharmacy and I didn't take it seriously until I got pretty toxic myself. I LOVE grapefruits & grapefruit juice and I miss them a lot. I also tend towards side effects and toxicity.
1175033 tn?1492201228 com/health/food-and-nutrition/AN00413 Grapefruit juice, and other grapefruit products and certain other citrus fruits can interfere with several kinds of prescription medications. Don't take these interactions lightly, as some can cause potentially dangerous health problems. Check with your doctor or pharmacist before consuming any grapefruit products or citrus fruits if you take prescription medications. You may need to eliminate grapefruit products from your diet.
Avatar n tn Wow looks like i should have read the warning label when my doc gave me to take them PRN or as necessary to re convert myself......okay i just went off of the site and read up on the label...they are telling us not to take it with the citrus because it effects how our body absorbs the Multaq for maximum performance of the med...if it were me and i had to take it on a daily basis i probably would stay away from all citrus drinks for sure because you want to give yourself the best shot possible...
Avatar f tn This may seem to be a silly question, but has anyone heard from their doctors not to combine methimazole and grapefruit? Online research seems to say it's not flagged as interacting but also notes that no studies have been done to see if it does interact. I was wondering if anyone's doctor had said anything? My doc is on vacation and I was gifted with a lovely and delicious looking 24 grapefruits.....
1815939 tn?1377991799 Grapefruit juice and grapefruit also interacts negatively with some anxiety meds (Alprazolam, for example).
Avatar n tn Hi Chicky Watch out for interactions with grapefruit juice and meds. I went on Zoloft in anticipation of beginning treatment. Then read about the grapefruit juice-turns out they use the same enzyme to clear your system so you can get too much of the drug in your system and get liver toxicity. Grapefruit acts that way with many drugs, so check first, then drink up.
Avatar f tn i need to know that, what is the interaction between juices of Grapefruit and Hepatitis C? is there any reactions of Grapefruit juice being taken by Hepatitis C patient?
Avatar m tn If narigenin is grapefruit then it is definitely not a good idea. I didn't know what narigenin was but, if I had, I would have more strongly advised against it. Don't eat grapefruit while taking Prograf is one of the first things I was told and told many times immediately after transplant. "Do not consume grapefruit or grapefruit juice during treatment with Prograf unless your doctor has told you do(sic). Prograf can have a dangerous interaction with grapefruit or grapefruit juice.
Avatar n tn It went on to mention certain prescription drugs that are affected by eating grapefruit and its juice. Typically, I eat two grapefruits a day! When I called my pharmacist, he said that it wasn't a drug that showed a high incidence of interaction with grapefruit, unlike the cholesterol lowering drugs. (Internet searches clearly showed that there is a connection). The pharmacist did however, say, that I should skip that night's dose and try to taper off.