Gleevec and side effects

Common Questions and Answers about Gleevec and side effects

gleevec

Avatar n tn I was diagnosed with CML in May with WBC at 222 and an enlarged spleen. Currently on Gleevec 400mg and the last FBC shows WBC at 2.1 . Still maintaining current dose of 400mg.Apart from some annoying blisters on my palm, other side effects rather acceptable.
Avatar f tn I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
Avatar n tn You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great. I hope this helps you. I would be glad to help you with any other questions.
Avatar n tn Myelosuppression with neutropenia (decrease in neutrophils) and thrombocytopenia (decrease in platelet count) can be a side effect of treatment. Usually, discontinuation of drug intake is advised until the blood counts increase. You should have your white blood cell count repeated after 1-2 weeks and see if it already improves. You should report to your doctor if you experience any symptoms like fever.
Avatar m tn Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count. This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
Avatar n tn I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
Avatar m tn I fear that I have diastolic dysfunction of the left ventricle, which is a side effect of the Gleevec. I saw my cariologist 2 years ago and he said I had some slight thickening but nothing to worry about. I am a 44 year old male, 5'9 200lbs (I know slightly over weight). I have told my PCP and my Hemotologist how I feel and they never seem concerned or worried and consider everything CML related. I feel that I am seriously ill.
1004138 tn?1316251113 OTOH, an antioxidant substance like melatonin might actually enhance the cancer-killing power of the drugs used in ovarian cancer, and it possibly reduces adverse effects of other drugs (like doxorubicin) without reducing their cancer-killing power. Everything needs to be individually researched.
Avatar f tn i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
1414174 tn?1304680526 I started noticeing side effects at about 8pm, and they continued till this morning. I experienced a low grade headache, aches in my upper legs and lower back, some difficulty sleeping, and an awkward kind of dizziness (which I notice now seems to immediately follow my Riba dose). I am a Genotype 1b, with what I was told a 6log Viral load?? I have clean and sober for over 6 years, and am pretty sure I contracted the virus about 7-8 years ago..
7829857 tn?1401192659 I am grateful to have been cleared at the 4 week mark. I was just feeling that the side effects were getting worse and worse and i was battling discouragement. I am very grateful for your help and admire the way you are handling this!
Avatar f tn I am 55 yrs old female and went for a physical and was told i had high blood presure, that day it was 144/92. I had a blood test and it showed high cholesteral 257. Doctor put me on 10 MG Lisinopril. I took the tab for 5 days on the fifth day my heart was pounding so hard in my chest and i felt like someone was sitting on my chest. This happened a few more time over the next week and it would go away after a few min.
Avatar m tn 22 days on sovaldi-olysio-no side effects,not even a headache.And to this life long non responder who has done and failed with everything that has been on the market,this combo is working.Cant believe I am getting better and not suffering like I did with all the previous poison.Its like Dr. Bones McCoy from Star Trek brought this stuff back from the future.
Avatar n tn I woke this morning with aches and pains and have been experiencing a headache on and off all day that is when I am not SLEEPING. Honestly I am not complaining especially since I had expected much worse. My question is do the symptoms change or/and get worse as treatment continues. I would assume they do get worse since the meds build up in your body. I have 3 kids ages 16,11,and 7.
Avatar f tn This treatment has a high risk of psychiatric side effects, you need to find a doctor who is up to date on the treatment and side effects. Search the archives on this forum, its got lots of good discussions and information. Good luck.
Avatar f tn Did you taper off the vibryd or quit abruptly? You can't just switch from one medication to another even in the same class and avoid withdrawal -- these meds are not easy to stop taking and it must be done carefully. Unless you completely stop taking a medication before starting another it's impossible to tell if your symptoms are a sign you're suffering withdrawal and quit too quickly or are side effects of the new medication.
Avatar f tn You definitely need to get some high quality moisturizer and start lathering your body with it. Also note – hot water dries out the skin. If possible, you might feel better if you skipped a daily shower when possible. The nausea stinks big time. The Pegasys folks are pretty clear that this particular side effect doesn't last and in my case it didn't. After about a month it went away. Try to eat small, frequent meals. Anything you like. Cold food is better than hot food.
Avatar f tn The known, serious side effects of tamoxifen are blood clots, strokes, uterine cancer, and cataracts (see Questions 5–8). Other side effects of tamoxifen are similar to the symptoms of menopause. The most common side effects are hot flashes and vaginal discharge. Some women experience irregular menstrual periods, headaches, fatigue, nausea and/or vomiting, vaginal dryness or itching, irritation of the skin around the vagina, and skin rash.
Avatar f tn seek immediate medical attention if you develop any serious symptoms or side effects. and that these side effects may only occur infrequently, BUT SOME MAY BE FATAL. would this statement not really get you thinking.I never had any serious deseases but thought that the hep c would kill me. how irronic. those serious side effects are all that occur in our bodies, for some of us. I never experienced any thing like this before on the treatment.
Avatar f tn It could be a side effect of the methadone or even an allergic type reaction to it. I remember when I took Macrobid (antibiotic) for a urinary infection, I had a high fever (102.3) every time I would take it, so I called my doctor's office and they told me to stop it immediately because I was having an allergic reaction to it. As it turned out, my father had had this same type of reaction to it a couple years before.
Avatar n tn I had many side effects. Headaches, severe heartburn accompanied with hiccups. Blisters and discoloration all over my tongue and back of my throat. By day 6 my feet and ankles were badly swollen and it was getting difficult to swallow. My doc said I was having a systemic reaction and to quit immediately. We are going to try Subutex now and I hope it works. On all the info I found, the only side effect I had that was listed was headache.
Avatar f tn I was just thinking about the pain during labor and im super nervous on what i should do.me and pain dont get along! Are the side effects from a epidural really bad and do it last a lifetime ?