gleevec and pregnancy

Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count. This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.

I was diagnosed with CML in May with WBC at 222 and an enlarged spleen. Currently on Gleevec 400mg and the last FBC shows WBC at 2.1 . Still maintaining current dose of 400mg.Apart from some annoying blisters on my palm, other side effects rather acceptable.

I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.

t want to see me, that fever was not from gleevec, and that I needed to monitor myself by myself by simply taken ibuprofen. This is what I did all last week and only this Monday he did a blood work. For now, what can I do to help my body to build my immune system back? Any vitamins? I'll appriciate any advice.

I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.

I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.

You might find he starts to be able to tolerate the pill. Gleevec is first choice for treating CML, and if he is doing good in every other way then encourage him that he is doing great. I hope this helps you. I would be glad to help you with any other questions.

i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.

No there is no herbal treatment for CML!!! Were you diagnosed with CML, and if so are you seeing a specialist and what treatment are you on.? I am being treated for CML, and was told not to even drink herbal teas well on my medication. Share some more information so I can help you. I have had CML for 13 years.

I am a Leukemia Survivor also. What type of Leukemia did you have, and what was your treatment. I have CML, and have achieved a major molecular response through a oral chemo drug called Gleevec. It does not sound like these patches have anything to do with the Leukemia. I would see a Dermatologist to have them evaluated. I hope that helps you a little bit.

I should mention that I have CML but it has been in remission for the last two years and I am no longer taking Gleevec. I am scheduled to be looked at by a group that kills the nerve endings in the heart that causes AF but there is an 18 month waiting period. My question is how many times can I be cardioverted and what is the downside of having it so often?

Lord, please give Becky the miracle you can do. She deserves to get a break Lord, and so does Ty. Hold her in your hands Father and let her feel you when she is down. In Jesus name, amen.

* buprenorphine Metabolized into norbuprenorphine by cytochrome-P450 isoenzyme 3A4 * Tyrosine kinase inhibitors, including Gleevec and Tasigna, used to treat chronic myelogenous leukemia and gastrointestinal tumors.

I was diagnosed w/CMML in 2009 and did 6mos of Vidaza. Monocyte levels keep rising and are now at 28%. 54 yr old male. My drs. just keep telling me to watch and wait, but I don't feel comfortable doing that, especially since I am fighting a recurrent staph infection that keeps returning every month.

She then went to Mayo and the doctor there told her she did not have Leukemia based on her blood work there, but she had been overdosed on Hydrea during the summer to the point her wbc was 3 and was only recovered to 11 by the time of her appt in Sept. Now her wbc is 58 and her hometown doctor is putting her back on Hydrea. Her family is concerned she is going to take a serious chemo drug when there is still a question of what she has. Could it be an infection that isn't showing up?

If pregnancy occurs, progesterone is produced in the placenta, and levels remain elevated throughout the pregnancy. The combination of high estrogen and progesterone levels suppresses further ovulation during pregnancy. Progesterone also encourages the growth of milk-producing glands in the breast during pregnancy. High progesterone levels are believed to be partly responsible for symptoms of premenstrual syndrome (PMS), such as breast tenderness, feeling bloated, and mood swings.

Louis and the founder of Rare Genomics, a nonprofit organization that designs treatments for rare childhood diseases based on individual genetic analysis, “we have drugs that target specific cancer mutations. Examples include Gleevec, Zelboraf, and Xalkori. Vertex,” a pharmaceutical company based in Massachusetts, “has famously made a drug for cystic-fibrosis patients with a particular mutation. The genetic targeting of individuals is a little farther out.

Watch Out For Interactions with Tamoxifen (Nolvadex) Breast cancer is the most common cancer in women and tamoxifen (NOLVADEX ) is used commonly in the treatment and sometimes in the prevention of this disease. In 2007, 1.7 million prescriptions were filled for tamoxifen. However, recent evidence suggests that certain other drugs can reduce the anti-cancer effects of tamoxifen, potentially increasing cancer recurrence and reducing survival.

did you tell your doctor you're late?

Of these, Free T3 is the most important because Free T3 largely regulates metabolism and many other body functions. (note that Free T3 and T4 are not the same as Total T3 and T4). From just looking at your lab results in light of my experience, I see nothing there to be alarmed about. Your Free T3 is above the midpoint of its range and Free T4 is also within range, though it is in the lower quarter of the range.

However this does not happen in early pregnancy. Also pregnancy cannot be diagnosed based on symptoms only. If periods are missed then a pregnancy test can be taken. Serum HCG levels and an ultrasound scan will help confirmation of pregnancy. Hope this helps.

I learned I had PCOS at a early age, I was 16 (currently 31 yrs old) I had started my periods when I was 11 and then by the age of 16 I had nothing! was put on the pill to regulate but since I wasn't sexually active at the time I forgot to take them all the time. Got back on the pill at 18, went off the pill at 26 (2006). Continued to have a period that first yr off the pill. Then 3 times a year, and then nothing from 2008 - 2009.

I'm 7 weeks pregnant and contracted a uterus infection and my doctor prescribed me two cycles of 1000mg of azithromycin and I'd love a second opinion!

Gleevec and pregnancy

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