Hi, I don't know the answer -- but since both CML and Gleevec toxicity produce anemia because of marrow suppression, maybe it's not possible to tell the difference. E.g., both would show a low reticulocyte count.
This full text paper on anemia from Gleevec https://onlinelibrary.wiley.com/doi/full/10.1002/ajh.23879 shows that other signs such as red blood cell size can vary, so that doesn't seem to help. Sorry.
I was diagnosed with CML and given Gleevec 400 ml. After taking gleevec for 2 weeks doctor took additional blood test. My WBC dropped from 36.5 to 7.1 and all other blood counts came down to normal range. I'm wondering if gleevec could give such fast hematological response or I was possibly misdiagnosed originally. I don't and didn't have any symptoms, my spleen and liver weren't enlarged, no enlarged lymph. Should I get second opinion asap? Please, help me.
t want to see me, that fever was not from gleevec, and that I needed to monitor myself by myself by simply taken ibuprofen. This is what I did all last week and only this Monday he did a blood work.
For now, what can I do to help my body to build my immune system back? Any vitamins? I'll appriciate any advice.
I was diagnosed last year and was immediatley put on gleevec 400mg/day.At my last consult my metabolic stats had risen,hence blood tests to determine if the gleevec is no longer working.I am still in firstphase and wonder what my options are if the gleevec is no longer an option.Amin pretty good form,just very tired and a lot of bone pain.
I have CML and was treated with Gleevec for 4 years and achieved remission. I have for the past several months been experiencing sudden onset of weakness which last for hours, to days. My blood pressure which has remained under control for several years with atenolol has been running 145/105 and higher for the past three to four months. I have a feeling of fullness in my stomach, and I have sporatic episodes of mild coughing, this occurs maybe once a week.
Fortunately for me I have a fantastic Dermatologist who explained the Melanoma was very shallow (.2mm) and was able to remove the Melanoma with a wide excision.
Now, fast forward 17 months and 11 other mole removals. My Primary Care took some blood work and noticed one of my liver enzymes (SGPT) was mildly elevated (60). Since I had Melanoma she sent me to get a cat scan of the Liver, gallbladder, pancreas and all the other goodies in the RU quadrant.
m a 28 year old male, not super fair skinned, Mediterranean descent, with no family history of melanoma, and no major sunburn as a child. After becoming curious how many moles I had, I counted 117 total across my body, with the vast, vast majority being tiny spots, like pricks of ink from a pen. Most of them are on my arms. I'm actually not sure if they're all moles or if some are freckles, but I decided to count them all as moles just to see what the number looked like at the end.
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What’s concerning, no scaring the hell out of me is that to my knowledge, you can’t just TELL the difference between an atypical mole and melanoma just by looking at it. And the fact he called it atypical means it shares visual characteristics with melanoma, which to me means IT LOOKS LIKE MELANOMA. I don’t know if his use of the term “right now” was a definite or if he just wanted to ease my mind but with a disclaimer.
For your own peace of mind, see your primary care provider (PCP) and see about getting a referal to a dermatologist. Even a PCP can determine if there is any reason to be concerned about Melanoma, but a dermatologist is still a good doctor to go to. If cancer is still suspected, either the PCP or the dermatologist will refer you to an oncologist. Nevertheless, it might not be Melanoma. So, don't hit the panic button just yet.
The best one is Melanoma, which is pure and natural. Melanoma is what the staff at a rehab center had me on after day 4 from pain killers and benzos. Also explain this to your doc, he might write you a very small prescription of Ambien. I mean a small amount like 5 or 10 at the most. But try the melanoma first. Great job!!!!!!!!!!
Hello,
I can understand your concern regarding melanoma. It is the most common cancer in women aged 25-29 years and is second only to breast cancer in women aged 30-34 years. Hereditary factors are important causes and similarly sun exposure increases the risk. But there are many other risk factors also like atypical/dysplastic nevi (particularly >5-10) and common nevi> 100.
Melanomas are usually >6 mm in size,with irregular borders ,asymmetrical and dark in color.
i get my heart checked every 2 weeks now and i am fine with the qt thing. i take the chemo pill called gleevec and have to force myself to eat so i dont get sick when i take it. how long will these withdrawel problems go on? i have xanax to take (1mg) but dont work to good. i should would appreciate any advice from any one on how to deal with these issues, family dr says its anxiety but i think its the withdrawels from the high dose of elavil.
Melanoma-astrocytoma syndrome. People with this rare condition have an increased risk of melanoma and astrocytoma (a type of brain tumor). The specific gene for this condition is thought to be located on chromosome 9. Families with both melanoma and brain tumors have been shown to have alterations in CDKN2A that affect the p14ARF protein."
You can get the genetic testing for this if you are worried.
thank you for commenting, I have 2 other kids who have appointments with the dermotologist coming up, both again have many freckles and moles. My son's melanoma was on his face between his eye and temple and the freckle grew and turned black very quickly, it was just over early detection. He had to heave a large skin graft and sentinal node biopsys done. 3 nodes were negative but 2 had "nevic, mole cells" in them.
One other question, does this mean I have a high chance of developing melanoma? I had a mildly dysplastic mole last year and then this. I have virtually no moles and only a few freckles, no family history and I take aspirin daily (supposed to reduce melanoma 30%) to prevent recurrence of colon cancer.
Now I am terrified that it was a melanoma and I have scrapped it off and the cancer will start growing without me knowing. Can you scrap off a melanoma? If it was a melanoma will the pigmentation grow to the surface again? Does melanoma heal? I know if I go to the gp they will not refer me to a dermatologist and can not afford to pay privately.
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