I'm a 50-year old male, who was diagnosed with MS in 2000. I've had two major flare-ups (exacerbations), primarily related to balance, spasticity, optic neuritis, and lack of sensation from the waist down. I've not had any lasting nerve damage, other than slightly off-kilter balance, occasional optic disturbances in my left eye, and dampened sensations from my knees to my feet. I'm still ambulatory and work 40 hours a week.