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Filgrastim risk

Common Questions and Answers about Filgrastim risk

neupogen

493068 tn?1224765315 my stats seem to go up and down so I only have to take it now every 2 wks. It is unknown whether filgrastim (Neupogen) increases or decreasses an individual's risk of developing cancer. Based on limited long-term data from healthy people ( if a person is healthy why would they need neupogen in the first place ) who have received filgrastim, no long-term risks have been found so far. good luck to you....hope this helped!
Avatar m tn Do you mean filgrastim? And are you saying Dengue fever? It would be a surprising though perhaps not impossible use of filgrastim. Dengue is usually treated by pain managers and sometimes hospitalization and a blood transfusion. Anyway, if you have a legitimate prescription from a doctor, you should be able to fill it in the United States.
Avatar f tn For this reason, patients are prescribed antibiotics and even receive injections to increase white blood counts (such as filgrastim or lenograstim). If this 0.4 value really pertains to your white counts, then I believe this is really low and what you are experiencing is a condition called 'febrile neutropenia'. I would suggest you ask your doctor about filgrastim or lenograstim injections aside from the Levaquin. Regards.
Avatar n tn Filgrastim is also prescribed as pegfilgrastim (called Neulasta). My doctor used the 500 neutrophill count as a cut-off, so every time I got down around 500 I used Neulasta. The interferon drops neutrophils and platelets. Some people can do okay with low neutrophils but just as many end up with kidney and sinus infections, etc., that make you even more miserable.
962875 tn?1314210036 that are expected to cause neutropenia in a significant proportion of patients. Some oncologists would perhaps use this even when risk of neutropenia is a little lower, as in the "AC" regimen. The side effect profile of filgrastim is not too bad, with transient bony pain being the only common complaint. All the best, and God Bless.
1986676 tn?1329862471 Musculoskeletal symptoms have been the most frequently reported adverse effects of filgrastim therapy. Bone pain has been reported in approximately 22% of patients. Reactivation of pseudogout occurred in a patient receiving chemotherapy. Postmarketing reports have included decreased bone density and osteoporosis in pediatric severe chronic neutropenia (SCN) patients receiving chronic treatment with filgrastim.
Avatar m tn Doctors unable to give any explanation for such wide variations on a dose to dose basis. Till date, I have also taken 5 doses of Filgrastim - the WBC Stimulator. Can you pleae advice possible reasons for such wide fluctuations.
687700 tn?1227103821 Nonetheless, there are several things that you can do to reduce your risk of getting an infection when your white blood cells are low, So what are the chance of incrise my cell count ?
Avatar m tn Neulasta® (pegfilgrastim) or NEUPOGEN® (Filgrastim) may reduce your chance of getting an infection, but it does not prevent all infections. An infection can happen anytime your neutrophil counts are low. Look for signs of infection, such as fever, chills, rash, sore throat, diarrhea, or redness, swelling, or pain around a cut or sore. If you have any of these signs, contact your health care professional immediately. http://www.neulasta.com/starting-chemo-with-neulasta/about-neulasta-neupogen.
Avatar n tn Hi, With modern medical advances, especially effective anti-emetics, and growth factors (filgrastim), chemotherapy has become safer and more tolerable over the last decade or so. Hair loss will be your major side effect, and some intermittent illnesses may also be expected during the course of chemotherapy. But your overall long-term benefit will be much more than these temporary effects. All the Best!
476246 tn?1418870914 , the primary ‘rescue’ meds are (generic) epoetin alpha (brand names Epogen, Procrit, Aransp), and filgrastim (generic) (brand name Neupogen). We do have a platelet booster here that has been approved for cancer treatment; it is generically known as oprelvekin (brand name Neumega), but its use has not been FDA approved for HCV treatment to my knowledge; it tends to worsen hemolytic anemia, although we have had a few patients in forum that have tried it.
1391695 tn?1298139789 Conceptually, granulocyte colony stimulating factor use may overcome treatment-related neutropenia, maintain higher interferon doses and potentially reduce infection in high-risk patients, though clinical studies to recommend its use are lacking. Patient Selection Before using a granulocyte colony stimulating factor: Peginterferon dose has been reduced• o Peginterferon alfa 2a reduction from 180mcg/week to 135mcg/week o Peginterferon alfa 2b reduction from 1.5mcg/kg/week to 1.
Avatar m tn You can discuss ‘Neupogen (filgrastim) with the doc; this is a GCSF drug that stimulates bone marrow production of white cells. It is generally initiated when absolute neutrofils reach .500 or that vicinity; some docs allow closer to .350, depending on occupation and other matters.
2022648 tn?1328711666 Hello, this is my first time on this forum. I just wanted to see if anyone is having or has had some of the same problems. Five weeks ago I started a 48 week treatment for hep b with 180 mg Pegasys. The nurse gave me my first injection in my arm which hurt for two weeks. Since then, I've alternated the injection sites. Twice in my thighs and twice in my belly. I have these big, round, red rashes with bruises in the middle. They just seem to be getting worse.
163305 tn?1333668571 NEUPOGEN® ( Filgrastim ) Program is designed to assist those patients who are medically indigent (patients may be uninsured or underinsured). Eligibility is based on patient's insurance status and income level.
Avatar f tn I used Neulasta, the pegylated form of filgrastim. More expensive but supposed to hold your neuts up longer when they are getting stomped by the IFN (I have good insurance). No side effect problems with it at all and it took my neut level from .640 to 12 overnight and kept me out of danger level for about 6 weeks. Better than an interferon reduction if patient is responsive to it.
Avatar f tn Neulasta is a peglated version of Neupogen which is also know as filgrastim. It's used to stimulate production of neutrophils, a component of whilte blood cells. It can be taken less often than regular 'ol Neupogen. I found it rougher than Neupgen in that it had some side effects, mainly bone pain. I found Neupogen to be side-less. Aranesp is Darbepoetin Alfa which is like Procrit (epo). It is also taken less often than Procrit.
443922 tn?1374157016 it was probably a term used so that you would get the concept. He was probably referring to Neupogen which is also known Filgrastim which is a human granulocyte colony-stimulating factor (G-CSF). Basically, it encourages the growth of the white blood cels that the Interferon depletes with treatment. For more information go to neupogen.com The riba, similarly, depletes red blood cell. If your hemoglobin gets low they might also prescribe Procrit for that. Go to procrit.
314532 tn?1206415109 So I posted a two weeks ago about my cbc counts being low and needing the aranesp and neulasta. I have been very sick thhis past week it has been awful! I have been waiting for our insurance company to authorize the meds. I called the doctors today to find out what is going on, the nurse told me that the insurance company said they won't authorize the meds unless I am in kidney failure. I don't know about any of you but to me that sounds kind of drastic.
Avatar f tn Yes, Neulasta is the pegylated version of Neupogen. A polyethylene glycol molecule or (“PEG”) is added to enlarge the Filgrastim molecule (Neupogen), thereby extending its half-life and causing it to be removed more slowly from the body. I don't know what the dosage requirements are for Neulasta but it is not taken as often as Neupogen.
Avatar m tn GCSF (Neupogen) is very frequently used for neutropenia but as I am sure you are all aware there is a very poor relationship actually between neutropenia and risk of infectious complications. Sometimes I really believe that when we treat with Filgrastim (marketed by Amgen as Neupogen) we are actually treating for ourselves more than for the patient. What I really believe is a more important issue in terms of treating infectious complications in cirrhotics is using prophylactic antibiotics.
Avatar f tn Briefly, Neupogen (generically filgrastim) is prescribed to increase low white blood cells as a result of interferon therapy. It’s also called a granulocyte colony stimulating factor, or GCSF drug. The labs used to track the need for this is the patient’s ‘absolute neutrofil’ count, located in the Complete Blood Count. Procrit (generically epoetin alpha) is used to stimulate bone marrow for production of red blood cells.