I am curious as why you do not mention that Glargine(lantus) does NOT have a license for twice daily usage ,levemir has a licensce for OD and BD and has weight benefits for type 2 patients???? or are you heavily sponsored/involved with the manufactureres of glargine? I am interested.
LANTUS is not intended for intravenous administration. The prolonged duration of activity of insulin glargine is dependent on injection into subcutaneous tissue. Intravenous administration of the usual subcutaneous dose could result in severe hypoglycemia."
This is because the effect described below, of forming microprecipitates below the skin, cannot happen in the blood stream. All the insulin in the blood is available immediately to the body.
I would continue to use insulin glargine, a recombinent insulin analogue (Lantus) without concern. This was the recommendation in the British Journal Lancet Vol 1, 374 issue 9649 p511-513 15 August 2009. The media has produced some fear based upon five studies that I have read, and used some statistical manipulation that would have failed me in "statistics one" in the eighth grade. The experimental protocols were pretty crummy.
She complained of polidypsia, dry mouth, weight loss. Insulinotherapy was initiated with glargine, ten units at bedtime (glycemic value before aministration was 169) after reiceiving 6 units of aspart imediately (7 pm). Next day a fasting value of 140 mg/dl. Bedtime value (2 hours postprandial ) 269. After 10 U glargine, fasting value 120 mg/dl. Glycemic variation are very important and depend on the thyroid status.
What is your opnion?
Hi Dawn,
Pizza can be tough to estimate, more because the carb content can vary so much from slice to slice and pizza to pizza. But although I'm just a mom like you, and not a doctor, it sounds like it's not just pizza causing high blood sugar.
You didn't say what sort of long-lasting insulin she's on-- is it Novalin? Or Lantus/glargine? If you haven't tried Lantus (aka glargine) yet, I would strongly recommend talking to your endo about it.
To my surprise it was 264. I am on 25 units of Glargine, 10 mg glipazide, which I take before bedtime. Why would my level be so high?????
Examples are insulin zinc suspension, protamine zinc insulin, and the insulin analogues insulin glargine and insulin detemir. The latter two insulins are now the most widely used long-acting insulins.
* Biphasic insulins: mixtures of short-acting and intermediate-acting insulins in different proportions, such as 30/70, 50/50. Examples are NovoMix 30, Humulin M3, Insuman comb and Humalog Mix25.
The doctor thinks it is too high and gave Recombinant Insulin Glargine Injection and my mother does 15 unit injection every night. But blood sugar is still like 7.3~8.3 mmol/L before meal and 9-10 mmol/L after meal.
Is this often to see among diabetes type 2 patients?
Can some one give me any advice about how to improve my mother's condition?
Sincerely thanks.
My blood sugars are out of whack and it just seems to be impossible to get them back to normal! I have just started taking glargine/lantus...but the control is still bad. Also, for those that have the pump...how is it and how has it affected your life style?
Montefiori Medical Center (Bronx, New York) performed an in-depth study of 240 women receiveing Lantus (insulin glargine) during pregnancy. The results were published in the Journal of Reproductive Medicine, April, 2009 (4) 208-10. They found the drug to be well-tolerated and advised continuing the use of Lantus during pregnancy. PubMed has no studies whatsoever that substantiate an adverse affect on pregnancy.
- http://en.wikipedia.org/wiki/Exenatide.
Getting control on the right-for-you medication is not easy. I have beed T2D since 2007 and have been on a number of different Meds, some of which seemed to work but then longer term had problems. You must keep you chin up and work with your dr. to find the best contol for you.
Good luck!
t make sense why an A1c would be that high if he rarely shows high blood sugars on his monitors. Is he testing regularly? Is he on Lantus/glargine? (That really helped stabilize my daughter.)
Let us know, and good luck with this challenge.
Lantus (insulin Glargine) is a very SLOW release insulin, a so-called "24-hour" insulin. Because it does not rapidly alter glucose levels it is safe to use when driving. It isn't adviseable to increase the dose of Metformin. Other insulins have the tendency to rapidly (comparatively) alter levels of conscious and situational awareness. It is often prescribed together with Metformin and Glipozide. I would also hazard a guess that weight control is an issue.
My doctor just changed me to a new insulin - Glargine (Lantus) and I am sleeping now. They say that Melatonin helps but it usually only gets you to sleep and then you are free to wake up 4 hours later. If you are really suffering from sleep deprivation, try getting up at same time each day no matter what time you go to bed. When you get exhausted, you will sleep and you may start to correct the cycle.
Lactulose vs. Xifaxan to decrease the ammonia. And beta blockers vs. banding for the varices which I presume are esophageal. You will get variations of experiences here which are therapeutic relative to your anxiety and directive relative to the facts But go to your Hepatologist with these anxieties because you can manage the effects of cirrhosis. My best.
You just have to do it awhile and you learn what is low vs high (ie knuckle deep to reach it vs full middle finger vs full ring finger). Then soft vs hard would be the difference between your lips and nose. I know way to much information, but you asked;-) It is also best when you cervix is wet (ie egg white stretchy discharge). Just remember most fertile is SHOW--Soft, High, Open, Wet. Again sorry I can't help with open vs closed. Good luck.
Study Confirms Benefits of Vitamin E in Nonalcoholic Steatohepatitis
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