I suffered a mild stroke (blood clot) Consultant prescribed Clopidogrel but cannot tolerate side effects. Then consultant prescribed Dipyridamole. I cannot tolerate this either. Severe headache, vomiting and diarrhoea. Has anybody got a different medication they are on?
The adverse effects experienced are similar to those with use of adenosine. While adverse effects are less frequent with dipyridamole (47% of patients), they tend to be more serious than those associated with adenosine. The most common adverse effects of dipyridamole are chest pain (19%), headache (12%), and hypotension (4.6%). In addition, 12% of patients require aminophylline for reversal of adverse effects.
Persantine is dipyridamole, but you will have to get extended release tablets as the two asprin and dipyridamole should not be taken together. Don’t change the medications without discussing with your doctor. So, consult him and then decide.
Hope this helped and do keep us posted.
What is nonreversible apical inferior wall and what does it mean when they say no dipyridamole-induced reversible ischemia .there is mild defect in the apical inferior wall that is not reversible at rest.
While you are taking Aggrenox (aspirin/dipyridamole), you should avoid taking over-the-counter pain medicine, especially any other products containing aspirin or non-steroidal anti-inflammatory drugs (NSAIDs).
Also, Avoid alcohol, or drink a minimal amount, as the combination of Aggrenox and alcohol could cause stomach bleeding.
Some of the alternatives include aspirin, Clopidogrel (Plavix), ticlodipine (Ticlid), dipyridamole (Persantine). Another alternative is Heparin injection. Different situations require different levels of anticoagulation. It is important to discuss the best treatment option with a physician.
ECG last month showed SVES, RBBB. This week he has stress test with dipyridamole protocol, and injection of thallium-201. The result showed "evidence of mild, small to medium size, irreversible perfusion defect in the inferior/inferolateral wall (mid to basal level)." Could you explain what this means? Does he need to have surgery or pacemaker? thanks in advance for your help.
False negative imaging is especially common when exercise is submaximal or in dipyridamole/adenosine studies of patients with severe obstructions of all three major coronary vessels. False positive scanning may be caused by signal attenuation from an elevated left hemidiaphragm or from breast tissue. These artifactual defects can be identified by performing a gated perfusion study to assess regional wall motion.
Pharmacological stress Tc-99m MIBI scan was performed with Dipyridamole given at arate of 0.14 mg/Kg/min over 4 minutes followed by injection of radio tracer 6 minutes later.
Findings are: Peak stress images revealed hypoperfused infero-septal and apical segment, which showed reversal at rest.
Impression: Findings are consistent with infero-septal and apical reversible ischemia.
Thanks all!
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