“If you are unaware that a patient is on simvastatin and you give either boceprevir or telaprevir, the simvastatin level in the blood can go high and patients can develop muscle breakdown,” said Dr. Jensen.
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There is only one interaction that would be of any concern. Treatment with both simvastatin and niacin may result in muscle pain or tenderness or muscle weakness.
Using simvastatin together with niacin is usually not recommended, but may be required in some cases. If you are using both medicines together, your doctor may change the dose or how often you use one or both of the medicines. It is important to tell your doctor and pharmacist about all other medicines that you are using.
I am also on pravastatin 20 mg. I find diltiazem/xarelto interaction in only one place. Abt 10 days ago, started having diarrhea or several loose bm's per day. If this continues should I call the cardio doc re this problem or go see gastro doc?. I have had pancreatitis in past so have a gastro doc.
I am taking 40mg nexium once daily and have recently been Rx'd simvastatin (10mg). It's a low dose, but there appears to be a potential moderate interaction, possibly myopathy and shortness of breath. I called the pharmacist and he said that unless I was taking a higher simvastatin dose (>50mg), I shouldn't have a problem.
Atenolol can and often does have an additive affect when taken along with other beta blocking meds.
In my case, even though the Atenolol was only 25 mg, it was enough to cause several heart pauses (flatlines) of 3 to 4 second durations detected via an event recorder.
Regarding the interaction between Diltiazem and Tambocor, this is from drugs.com:
"Using diltiazem together with flecainide can increase the effects of either medication.
I like to drink grapefruit juice but hear that it can interfere with some prescription medications. Is that true?
Answers from Katherine Zeratsky, R.D., L.D.
Yes. Grapefruit and certain other citrus fruits and products can interfere with several kinds of prescription medications.
Don't take these interactions lightly. Some can cause potentially dangerous health problems.
Yes, I understand there is an interaction between victrelis and grapefruit and I learned it on this board too. Then I looked for the confirmatin on that and found it in Victrelis' labeling.
I don't believe either Victrelis or Incevik have been used to treat HIV. They were just approved in May, 2011, for the treatment of Hepatitis C. They are in a class of new drugs that target the specific virus and there are HIV drugs that do the same - but not the same drugs.
In most cases, the clinical consequence of the pharmacokinetic interaction has not been evaluated. However, for midazolam and triazolam, as well as for buspirone, impairment of CNS function was observed, and for the calcium channel blocker felodipine greater blood pressure lowering has been observed. In contrast to the increased levels of the other medications, the grapefruit juice interaction observed with theophylline and itraconazole was reduced plasma concentrations.
It really depends on what you need. If this has been prescribed for you, and you are uncertain about it, then you can always ask your doctor for more clarification. It really just all depends on your individual circumstances.
I quit taking the simvastatin last tuesday, and by friday I looked perfectly normal with no steroid cream......
Thanks again for all the help!
He prescribed Zarelto, Diltiazem and Amodarone. I asked that the gastro dr and cardio doctor consult and supposedly they did....but I don't feel real confident since they are in opposing hospitals. My husband and I are not real keen on these added drugs when the real problem is the harsh side effects from the Incivek. Do any of you have any insight into this. The cardio guy wants to see him in FOUR weeks....hell that is a long time to take extra medicines that might not be needed..
i have been taking tri-cor and simvastatin (40mg) for several years. Over the last 8 months i stopped taking the tri-cor because insurance no longer covered it and I decreased my simvastatin to 20mg. At the same time in increased my fiber significantly (metemucil and high fiber cereal daily) and began taking one 1000mg of fish oil each day. Lost a few pounds as well, I'm 41, 5'10" and 173lbs non-smoker.
I use simvastatin to lower the cholesterol and lisinopril to lower the bp. The lisinopril works w/o the simvastatin and v.v.
Amlodipine is a calcium channel blocker while lisnopril is an angiotensin converting enzyme(ACE) inhibitor. Both groups of drugs and simvastatin are unlikely to cause erectile dysfunction. However yes, all three of them can cause swelling of ankles. Talk to your doctor. You can change your medications. Among antihypertensives you need to avoid thiazides , beta blockers and alpha blockers.
High blood pressure and reduced blood supply to penis can also cause erectile dysfunction.
I have been on 20 mg of simvastatin and 3000 mg niaspan now my ck levels have went from 60 to 295 i could hardly walk .will my levels come down if i lower dose. and reverse damage. i have 12 stents .the rest of my blood work is fine.
I have suffered with taking diltiazem(180 mg ER) AND metoprolol (50 mg ER) for atril fibrillation for the past two and a half years. The side effects have been debilitating.. Both drugs have the same side effects and together and one or the other or both create what I can only describe as chaotic turbulence in my chest and pain in my left arm when the second drug kicks in.. My cardiolgist now wants me to add a blood thinner (xarelto) to my meds menu.
Not all of us respond the same to the same medications. The indapamide worked better for you than the dilitazem so it only makes sense to stay w/the indapamide and forego the diltiazem since your doctor obviously didn't consider the indapamide and diltiazem a good combinantion.
I understand about uninsured doctor visits. We lost our family doctor of some 30 years and got a rude shock when we started doctor shopping!!! From a standard $35 office call to a $150 initial office call!!!!!
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