Ask your ophthalmologist about putting you on a steroid drop like lotemax for several weeks to stop the cyclosporin burning.
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Is Cyclosporin a steroid ? My consultant has advised against steroids previously as I had Herpes Simplex Keratitis a few months ago which she said steroids could stir up again. The HSK was very painful and definitely don't want that again although she has warned ne it can reaccur.
Even with ceseation of cyclosporin and a decrease in viral load a reading of 1,142,00 IU/mL is considered high.
Importantly here is your daughter currently has minimal liver damage and will be having iron chelation therapy to prevent fibrosis acceleration. The BMT was succesful and that aspect of her health is under control . As time passes, the only thing that will confirm the presence of active HCV is an HCV RNA by PCR.
Yes i got a nerve conduction test done, a mri and a needle examination done. I have no numbness or pain or.I did use to have a pain down my left leg and a serve pain in my lower back/cox in the mornings however both these are now gone. As far as i know i have no other symptoms just the muscle weakness in the lower half of my body.Its nearly like my left leg is dead when walking.
My ophthalmologist recently prescribed restasis for dry eyes. I read that cyclosporin can causes cancer. Is this true? Are these drops safe?
I just had a "Eureka!" moment. I have been researching possible causes of my CFS and finally found something that explains how and why my exhaustion occurs. Dr Sarah Myhill has written a book and posted it for free download from her website www.drmyhill.co.uk
I have read so many articles about CFS that detail possible causes and proposed treatment plans, but no other doctor had illustrated, step by step, just how the mitochondria in our cells make energy so that they can function.
Cyclosporin (brand name Atopica) is a relatively new oral medication which can be used as a non-steroid way to reduce allergic skin inflammation and itching. It is helpful in approximately 80% of allergic dogs to control itch. Cyclosporin is given orally daily for 4-6 weeks, then the dose and frequency is slowly decreased to the lowest possible dose needed for comfort.
Also, as a result of being on such a high dose of cyclosporin I tended to feel very sick for 2-4 hours after taking the medicine (fever like symptoms). If I did not carefully avoid sick people I would become extremely ill and even at one point was hospitalize for 4 days because my immune system grew so weak. Infections began to appear on my legs over time and I began to take antibotics along with the cyclosporin.
While the inhibition of cytochrome P450 and its isoforms P2E1 and P3A4 is advantageous to protect your mitochondria from the damage caused by the hep c virus and to inhibit the virus from replicating, it can also inhibit your body's ability to metabolize some of the drugs you may be taking, exposing you to the possibility of overdose.
Anti-mitochondrial antibodies (AMA) are autoantibodies, consisting of immunoglobulins formed against mitochondria,[1] primarily mitochondria in cells of the liver. The presence of AMAs in the blood or serum of a person is indicative of several autoimmune diseases such as primary biliary cirrhosis (PBC) (a scarring of liver tissue, confined primarily to the bile duct drainage system of the liver). It is present in about 95% of cases.
org/user_journals/show/1648149/General-information-on-dry-eyes-tears-dysfunction-syndrome
Both my wife and I have very dry eyes and both of us have been on Restasis (cyclosporin) for years with excellent results. I understand from postings from the UK this is difficult to get there.
He told us to wait till the cyclosporin is stopped. When the cyclosporin was stopped, we waited for 45 days and had a HCV quantitative done. It was 1420000IU/ML ie 88% less than the last test conducted and SGOT/SGPT levels were 60/109. I had also gone through some articles on HCV which stated that out of 100 people who gets infected, 15 will get rid of the virus without any treatment.
But on the other hand, the Hepatitis C virus damages the mitochondria in liver cells (by a process of oxidation). Once the mitochondria are damaged, they send signals to the liver cells to die.
Since Vitamin C protects the mitochondria.... then taking Vitamin C would protect liver cells. So in theory, Vitamin C should be beneficial for HCV.
On a sort of related topic....
The ER doctor diagnosed me with Herpes Keratitis yesterday. I had been taking Restasis(Cyclosporin eye drops BID) and had many of the symptoms of side effects of that drug including low neutraphils, redness and swelling of eyelids, itching, feeling of foreign object in my eye, pain on administration of drops.
I believe this is a drug reaction not Herpes Keratitis. What do you think?
A related discussion, <a href='/posts/show/1223231'>Thyroid & Mitochondria</a> was started.
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