Liver Cancer Cells Coaxed To Commit Suicide By Common Anti-Inflammatory
The anti-inflammatory drug celecoxib, known by the brand name Celebrex, triggers liver cancer cell death by reacting with a protein in a way that makes those cells commit suicide, according to a new study.
Researchers also found that the combination of celecoxib with each of two chemotherapy drugs killed more liver cancer cells in culture, making those combinations more effective than either drug on its own.
A man aged 81 was taking celecoxib 100mg daily following knee replacement surgery for osteoarthritis. Three weeks after commencing celecoxib he developed jellybean-shaped loss of vision centrally in each eye. This occurred every day after his morning dose and lasted for a few hours. The celecoxib was stopped and there was no recurrence of the visual disturbance.
I was just thinking this morning that you sound a little like my GP. While my GP says everything is stress-related, with you, it is responsibility-related.
It's interesting how I seem to complicate even the most basic thing(s).
It was just an observation. Something which says more about me than anything else. Other than being guided, by others, towards principles that may elicit change.
Do you think me seeing my GP weekly is excessive?
How do people/ patients learn to take responsibility for themselves (and their thoughts, feelings and behaviors)?
Responsibility can feel like an elusive trait/ characteristic.
Is responsibility also just a name? Can we ?obtain/ achieve it by accepting and confronting reality?
Emotional eating and mental health issues all come back to taking responsibility, don't they?
How does one take responsibility when one is stuck?
t seen anything positive about Celecoxib. My question is how long should I wait until I start taking this on a regular basis. Because, I have had many alcoholic drinks in my time, but if I stay sober should I be able to take this within 2 weeks? I'm only saying that because I'm assuming it might be a good window opportunity for my liver to start healing!
Ah thanks for your comment,, I have tried celecoxib and arcoxia as my doctors advised but I already got immune with this meds as they can't controll the pain anymore..
On the subject of personal responsibility, do you believe that if a person is feeling suicidal that that is their sole responsibility? I'm feeling confused about a lot of things. I just don't want to make a mistake because I don't understand.
Is this manageable alone if I concentrate on reality? The reality where things unfold naturally. Is working through my emotional eating issues enough for now?
"Go back to your reality and make your life work." Is this enough?
Does the referring dentist have any responsibility if there's a problem with what happened with the procedure that the dentist that he referred me to did?
I just did one after I fell and found out that I should not even be on half the medications I am on due to my Celecoxib. So I ended up falling the other day and really messed up my right ankle, low back, neck and right wrist. I was out camping with the hubby and so I took a couple of Benedryll to help me sleep since I was in so much pain...Very Bad Move, it dropped my Blood Pressure way down and caused me to be sensitive to the sun and get sunburned. I was so dizzy.
I have a 3-4 week old puppy that has swelling on her neck and left side of jaw it is hard around the swelling area.she is breathing ok,nursing well and she cries when i touch it...i wanted to know if any one has any ideas to help the swelling go down.if you May know what this could be pls be free to comment...i do not have enough money for the vet right now but im working on it .....i am hoping it's just an ant bite or something but I'm wondering why is it so big..the skin is tight....
m in treatment and working in a position of some responsibility (not in the medical field) in a small town. I wanted to keep my dx and tx to myself but it didn't work out that way. Because the information is out there I quit trying to hide it. If someone asks me anything I answer. If it's how are you I answer that I'm still putting one foot in front of the other and change the subject.
I work in a nursing home and I'm going on mat leave at 35w + 3d tho I'm taking 2 weeks annual leave before that so ill actually be off for 33w + 3d. I've dropped my hours down to 30 instead of 40 for these last few weeks because I'm finding it hard and feeling bad that I can't do stuff to help my colleagues.
I had trouble nursing with my first baby. Ouch, is all I can say. At one point, on day three of being home, he had blood coming out of his mouth. What was that blood? Oh, just his latching on incorrectly causing me to have cuts. Like for real, it was that bad. I was about to give up completely at that point but my darling husband went and called Le Leche league to talk to me.
Celebrex or celecoxib, on the other hand, is used to treat pain or inflammation including headaches. Medication effect usually varies from one person to another. What is effective to one may not be as effective to another. It would be difficult to say which medicine has a better outlook. You can take the celebrex as an acute medication while the topamax may be your preventive medication. Discuss this with your doctor for proper management. Take care and regards.
m a single mom and have been given feedback over the past couple of years that my son will not take responsibility for his actions. It has become maddening and is very much affecting my quality of life at this point.
Today I asked him to not slam the car door so hard and he insisted that he DIDN'T slam the door. The ensuing ordeal humbles me to my core.. I'm exhausted and feel frustration levels at this point that are truly unhealthy.
The same thing happened to me, Also have an allergy to Ibuprofen All of the Coxibs like celecoxib and even to ketarolac - as Dr_Veena said they do belong to NSAID group, however currently I'm very cautious in taking any drugs for headaches, different antipyretics like acetominophen and salicylates like aspirin.
What has helped me the most is Celebrex (celecoxib); It is an anti-inflammatory and unlike over the counter ibuprofen it is safer for your stomach. You want to target reducing inflammation, instead of killing the pain (such as with Narcotics). If you simply kill the pain, you will revert to habits like poor seating position or movement patterns that can exacerbate the injury -- deadly cycle. Ice does this, as well.
Don't feel bad for doing what you felt was right to protect your child. I also had to quit my job due to risk of miscarriage. All of the financial responsibility is now on my significant other. I'm sure you guys will make it work.
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