I also have a couple of cold spots on my lower left
leg that can be felt by the hand as well as my
leg. These things seem to plague me when I'm in a "flare up." Oh, and my hair falls out, but I'm not sure if that factors into this. I also have a diagnosis of Major Depressive Disorder for which I am on Welbutrin -long term. My mother is diabetic, my older sister is completely bedridden due to some type of neuropathy which severely affects her motor skills and more.