I took my first dose of Alendronate and then experience significant muscle pain for the next 4 days. Does anyone know if I should expect this to happen each time I take it or is it something to happen for the first few times until my body adjusts to the medicine?
Do you mean Fosamax (alendronate)? If you do, its for treating bone problems like Osteoperosis by adding bone mass and slows bone loss. I use it for Osteopenia.
The prescription drug Fosamax (the generic is alendronate sodium) is a medication which has been prescribed to hundreds of thousands of postmenopausal women to treat osteoporosis and help increase bone mass thereby reducing the chance of spinal or non-spinal fractures. Fosamax has also been prescribed to increase bone mass in men with osteoporosis. Brand name Fosamax is manufactured in the United States by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
The authors examined the effects of high-dose oral alendronate (40 mg daily) for 6 months on 3 adult patients with intractable headache due to fibrous dysplasia of the skull. Each patient had disease processes not amenable to surgery. The patients underwent clinical follow-up at 1, 3, and 6 months. Their pain levels were documented at each visit by using a visual analog scale. All 3 patients demonstrated a significant decrease in pain levels and became independent of scheduled analgesics.
Methadone has a slow metabolism and very high fat solubility, making it longer lasting than morphine-based drugs. Methadone has a typical elimination half-life of 15 to 60 hours with an average of i would say about 22. However, metabolism rates vary greatly between individuals, up to a factor of 100 ranging from as few as 4 hours to as many as 130 hours, or even 190 hours. So it's hard to say.
The water solubility of bilirubin allows the bilirubin to be excreted into bile. (Bile then is used to digest fats.)
Total bilirubin, if I remember correctly, is the conjugated hemoglobin, since there is also another portion that is not conjugated.
What the elevated total bilirubin means at this point is 'something' is going on, but you may need more information before your doc can determine the cause.
I am also taking Aromasin for bc. Stopped alendronate (I am osteopenic due to 30 yrs of prednisolone and Arimidex) in case this caused the oesophagitis. Would appreciate your advice.
thankyou,i am with contact of my doctor ,he said there is no solution for damaged vertibras,but calcium and vitiman d and alendronate sodium/cholecaiciferol tablets will help spine and bones from further damages but what to do with prednisones i cant stop them because of asthma and taking of them will damage other bones isnt there any other solution instead of prednisones, i know there is nothing accept these because my doctor told me:(
The authors examined the effects of high-dose oral alendronate (40 mg daily) for 6 months on 3 adult patients with intractable headache due to fibrous dysplasia of the skull. Each patient had disease processes not amenable to surgery. The patients underwent clinical follow-up at 1, 3, and 6 months. Their pain levels were documented at each visit by using a visual analog scale. All 3 patients demonstrated a significant decrease in pain levels and became independent of scheduled analgesics.
Osteoporosis medications like Raloxifene (Evista), alendronate (Fosomax), risendronate (Actonel) and ibandronate (Boniva) all can cause flu like symptoms in individuals that are taking them. I am not sure what medications you are on, but this could be your problem.
The main requirements for them are (1) high IFN-inducing activity, (2) absence of side effects, (3) wide spectrum of antimicrobial activity, (4) broad therapeutic security and, (5) good solubility in water and biologic liquids. IFN inducers stimulate IFN production in different cells and organs, and that determines the strategy for their application. Amixin (OOO "Lancepharm," Moscow, Russia) induces IFN-?/? production mostly in T cells. Cycloferon (NTFF "Polysan," St.
However, factors that can affect absorption include oral pH, salivary enzymes, lipid solubility, and molecular weight (molecules may be too large to pass through the mucous membranes). A sublingual product, specifically created to ensure effective absorption, is recommended.
(By the way, although losartan is currently being researched in Johns Hopkins clinical trials, other ARBs such as telmisartan are probably most effective given their increased lipid solubility and thus increased tissue penetration.)
I strongly encourage you to visit www.marfanlife.net and find the very lengthy thread titled "Losartan" or something to that effect. Probably some of the most important reading of your life.
the brain is affected quickly as alcohol will cross what is called the blood-brain barrier due to its solubility. this can compromise involuntary actions such as heartbeat, breathing and gag reflex. organs such as the liver and pancreas can suffer tissue destruction resulting in everything from lowered function and scarring to complete organ failure. for diagnosing existing damage, your doctor can order bloodwork including a liver panel to check things like enzyme levels.
Also, would it perhaps be possible to add some alendronate, or something else to help her bone density and still be able to benefit from the thyroid medication? Thank you so much!
Insulin glargine is a human insulin analog that has been designed to have low aqueous solubility at neutral pH. At pH 4, as in the LANTUS injection solution, it is completely soluble. After injection into the subcutaneous tissue, the acidic solution is neutralized, leading to formation of microprecipitates from which small amounts of insulin glargine are slowly released, resulting in a relatively constant concentration/time profile over 24 hours with no pronounced peak.
s, but this has exponentially been exacerbated by Arimidex. For the past 2 yrs I have been taking a weekly bisphosphonate (Alendronate), plus twice daily Calcichew/Vit.D to help prevent further bone loss.
Tamoxifen is prescribed for pre-menopausal patients, the AI's for post-menopausal. As I had a full hysterectomy some 19 yrs ago, I could go straight on to Arimidex.
Hi & Welcome!
A BB King fan, eh? Well, Congratulations on your 3 Days off Subs! While the majority of people I've known (including myself) to come off Bupe experience w/d's b/w 24 & 48 hours , some have reported that it 'ramps up'/intensifies between 72 - 96 hrs. Have you had any kind of opiate habit before? If not, it's just possible that you might experience milder w/d's than someone w/ a longer history.
Because of its small size, Ru can be easily conjugated to any protein ligand using standard chemistries without affecting immunoreactivity or solubility of the protein. In a typical agent-detection assay, a sample is added to a mixture of capture antibody-coated paramagnetic beads and a Ru-conjugated detector antibody. After a short incubation period, the analyzer draws the sample into the flow cell, captures and washes the magnetic beads, and measures the electrochemiluminescent signal.
Alendronate one tablet once a week for my Osteoporosis, Calcium 600 + D3 too. then I have Telfast 800 mg for my Allergie Rhinitis, Metformin 2 x a day 'cause I'm DM type 2, Simvastatin 10 mg - for cholesterol and Vit. E 400 IU. I took five years of Tamoxifen then changed to Femara because I have had Lumpectomy in September, 2003. Praise the Lord I am cancer free now. BTW I have also Rectozorin for my Hemorrhoid. It bleeds because I'm always constipated.
She had been taking 75mcg once per day. As well as 70mg a week of alendronate once per week for osteoporosis. This is all so confusing. When everything and everyone is contradicting themselves.
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