Tumor bulk did not progress during this interval in any patient. Overall, alendronate was tolerated well, although in 1 patient it was discontinued early due to esophagitis. High-dose oral bisphosphonate therapy is an alternative therapeutic option for the palliative treatment of patients with fibrous dysplasia of the skull.
This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.
Kevin, M.D.
www.kevinmd.
The prescription drug Fosamax (the generic is alendronate sodium) is a medication which has been prescribed to hundreds of thousands of postmenopausal women to treat osteoporosis and help increase bone mass thereby reducing the chance of spinal or non-spinal fractures. Fosamax has also been prescribed to increase bone mass in men with osteoporosis. Brand name Fosamax is manufactured in the United States by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.
The authors examined the effects of high-dose oral alendronate (40 mg daily) for 6 months on 3 adult patients with intractable headache due to fibrous dysplasia of the skull. Each patient had disease processes not amenable to surgery. The patients underwent clinical follow-up at 1, 3, and 6 months. Their pain levels were documented at each visit by using a visual analog scale. All 3 patients demonstrated a significant decrease in pain levels and became independent of scheduled analgesics.
I took my first dose of Alendronate and then experience significant muscle pain for the next 4 days. Does anyone know if I should expect this to happen each time I take it or is it something to happen for the first few times until my body adjusts to the medicine?
Do you mean Fosamax (alendronate)? If you do, its for treating bone problems like Osteoperosis by adding bone mass and slows bone loss. I use it for Osteopenia.
Thank you. Interestingly enough, my gyno referred me to the pharmacist and the pharmacist couldn't tell me anything I didn't already know from the internet- so-- if you would be kind enough to offer your opinion - ..... if the mechanism of action is to decrease osteoclasts (thereby dead bone cells are not removed) - is this helpful to have denser bones made of dead bone tissue?
I recently asked a quesrion regarding a patient with a small rectal cancer that could have been treated with radiation, but the radiologist consulted with does not recommend radiation as the patient had a cobalt implant 40 years ago for cervical cancer & thinks she has had too much radiation. She is 79 years old & NEEDS TO KNOW if there is another way to treat it without surgery requiring a colostomy.
After body has immuno response, such as produce antibody and huge amount of hiv specific killer T-cells, CD4 will have slightly increase, but CD8 has more significantly increase. Positive patient has CD4/CD8 ratio <1.
thankyou,i am with contact of my doctor ,he said there is no solution for damaged vertibras,but calcium and vitiman d and alendronate sodium/cholecaiciferol tablets will help spine and bones from further damages but what to do with prednisones i cant stop them because of asthma and taking of them will damage other bones isnt there any other solution instead of prednisones, i know there is nothing accept these because my doctor told me:(
Osteoporosis medications like Raloxifene (Evista), alendronate (Fosomax), risendronate (Actonel) and ibandronate (Boniva) all can cause flu like symptoms in individuals that are taking them. I am not sure what medications you are on, but this could be your problem.
Skull osteomyelitis presents with headache as the initial symptom and then as the areas of brain and cranial nerves supplying that area become involved,patient may present with variable symptoms depending on the same.
If you are having any such symptoms,then I would advise you to consult an orthopedician and get MRI of the area along with gallium bone scans.biopsy of the bone may be required to confirm the diagnosis.
I sincerely hope that helps. Take care and keep me posted Kind Regards.
Thanks, appreciate the information.
Hi!
If you were my patient, I would advise you that maybe the oral contraceptive is not the best option for you. There are patches and vaginal inserts that might work better because they bypass your stomach. There are also injectable and implantable contraceptives that are very convenient to use.
Starting and stopping birth control can cause irregular bleeding, so that is not too unusual. I always recommend a pregnancy test too though, whenever the bleeding is different that expected.
Does anyone know of any good patient information or a workbook to try and reduce risk of forming another stone ?
Welcome and yes you have found the right place. My heart goes out to you because it has to be so hard to know you need surgery, but can't have it. We have SelmaS that is on here and she send's out a lot of sites and information that will help u greatly.. This question was just asked a couple of mths ago. Memory brain I don't remember what they are. I just wanted to welcome you and to let you know your not alone. I have the same worry as you as far as my daughter.
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