Adalimumab vs infliximab
Common Questions and Answers about Adalimumab vs infliximab
humira
Though non steroidal anti-inflammatory agents (NSAID) and steroids are the gold standard of treatment, more emphasis should be laid on physical and occupational therapy, rest, heat pads and use of assistive devices for walking. Biological response modifiers like etanercept, leflunomide (used less often), adalimumab, or infliximab can be added in consultation with doctor.
Medicines prescribed for Crohn’s include fibre supplements, Aminosalicylates (medicines that help control mild to moderate symptoms), corticosteroids, medicines such as azathioprine or 6-mercaptopurine and biologic therapy like Infliximab and adalimumab in severe cases.
It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
Drugs called TNF-inhibitors (etanercept, adalimumab, infliximab), which block an inflammatory protein, have been shown to improve the symptoms of ankylosing spondylitis.
I'm going to refer your post to the Hysterectomy Forum, there is a wonderful CL there who will be able to tell you if there is something related to that surgery that could be causing these issues. (This forum is related to pelvic organ prolapse.)
Good luck, I hope you find some relief soon.
Hi
Just wondered if anyone has/knows about crohns and a fistula and stricture pain and ALSO is having Infliximab?? I have just started the treatment and am waiting for my fistula to heal so I can lead a somewhat normal life. Also I get a blocked stomach feeling every now and them which I assume is from a stricture....I am only 27 and have had this disease for 8 years, my large bowel perforated when I was 21 I had a bag for a year then it got reversed.
As there was no improvement. Doctor adviced to have Exemptia (Adalimumab) injection. 4 injections (40mg 8ml) was given. Next day he was having stomach pain, tight and rigid stomach, and fast breathing. He was immediately admitted in the nearby hospital and doctor found he was suffering from megacolon (toxic colon). After taking x-ray and CT scan, it was found that there was perforation in his stomach.
hi
i'm 15 and i have crohn's disease. i'm portuguese so i apologize for my english. i'm going to start a treatment called infliximab and i wanted to know if it's ok for me to continue smoking weed. i started smoking weed 10 month ago and nothing changed but i'm scared of starting this new treatment. i don't smoke a lot but i don't know the side effects of the 2 combined. i can't ask my doctor because my mom is always is me.
Yesterday my rheumatologist has finally decided to give me something other than anti-inflammatories and anti-depressants for my list of symptoms which he has decided are due to either Ankylosing Spondylitis, Psoriatic Arthritis (Palindromic Rheumatism was mentioned too) or possibly all of the above, with a side order of Fibromyalgia. Just wondering if anyone here has taken Humira (Adalimumab) as I've read about it and am freaking out a bit!
This was 270 when the norm is 5 or less. My gastro restarted the mtx, 25 mg weekly, and for the first time, introduced infliximab on the 0-2-4-8 weekly protocol. I think it was after some 6 months or so that I had the infliximab infusion on a Monday, delayed my mtx injection until the next day and had a violent reaction with pruple spots all over my body, very high temperature, nausea, vomiting, diarrahea and a pain up my spine.
My wife receives Remicade (infliximab) every 8 weeks, recently after fighting a cold/flu she was diagnosed with RCE and has gone through a number of ointments etc from her optometrist. She has another appointment Friday and may be referred to an ophthalmologist for more treatment options. The concern is she is scheduled in the next day or two for a Remicade infusion ( treating UC). Her concern is "will the remicade adversely affect the healing of the eye with RCE?".
Which is why so many of the biologic drugs used for those conditions, such as adalimumab (Humira), etanercept (Enbrel), and infliximab (Remicade) show promise for HS sufferers."
***
Excerpts from "Putting Hidradenitis Suppurativa Into Remission"....
"I decided to ask Loren Cordain about HS when I interviewed him at the AHS last summer. He mentioned that he thought HS might have an autoimmune component but other than that, he didn’t have any information.
Yes, Humira will indirectly help in controlling diarrhea and digestion. Let me explain this. Humira or adalimumab is a biological response modifier and tumor necrosis factor (TNF) blocker. Thus, in Crohn’s it will modify your body’s response to disease (bloating, tenderness, diarrhea, indigestion etc). This is because any immune mediated disease like Crohn’s produces excess of an inflammatory protein called TNF-alpha, which causes cellular damage along with pain and inflammation.
As most of us know Humira (adalimumab) reduces the effects of a substance in the body that can cause inflammation.
Common Humira side effects may include: headache; nausea;
cold symptoms such as stuffy nose, sinus pain, sneezing, sore throat;
rash; or redness, bruising, ITCHING, or swelling where the injection was given.
So what you are experiencing is not unusual - however I think you should give your MD a call as Sherry also suggested. He/she needs to know about your reaction.
While it is antihistaminics, topical and oral steroids for eczema and antifungal for fungal infection, the treatment of psoriasis that have been approved by FDA are adalimumab and Xtrac Velocity excimer laser system. Apart from that, topical medications like emollients, creams containing coal tar, dithranol, corticosteroids, fluocinonide, vitamin D3 analogues and retinoids have been routinely used.
So before using any treatment it is advisable to consult a dermatologist.
I hope it helps.
s flares, it goes up really high - 6 weeks ago mine was 190 and I needed to be hospitalised for dehydration and to recommence Infliximab. When I had a really bad flare last year, some 6 months after my first resection (right hemi-colectomy) it was an incredible 260 - my gastro treats a lot of Crohn's and UC patients, and he said he had never of a C-RP being so high. IV antibiotics, methotrexate injections and Infliximab infusions brought the level down, but it was touch and go at the time.
Taper off the steroids to low potency ones after consulting your dermatologist. The drugs that have been approved by FDA are adalimumab and Xtrac Velocity excimer laser system. Apart from that, topical medications like emollients, creams containing coal tar, dithranol (anthralin), corticosteroids like desoximetasone (Topicort), fluocinonide, vitamin D3 analogues (for example, calcipotriol), and retinoids have been routinely used. Phototherapy containing UV A has also been employed.
t stop me getting bc, and currently on weekly self administered 25 mg injections, since I switched from 2 yrs of Infliximab. I stopped the infliximab because of severe inexplicable weight gain and have now got my weight back to normal at 120 lbs - I am only 5' 2".
Over the years I think I have tried most drugs to keep the disease in remission and now find methotrexate has the least side effects which are tolerable.
s (Infliximab, Humira) which I started last July, so at least he is current with all new drugs. and....I trust him implicitly.
Protein? I have always had to follow a high protein, high carb, low fibre diet, so I tend to eat very little red meat, but lots of fish, chicken and game. I occasionally have calves' liver, because I like it, and it has a lot of iron.
I was on mtx tablets 25 mg weekly, then 25 mg injections (done at home weekly), but after having some serious flares and surgery (right hemi-colectomy) 3 yrs ago, I was put on Infliximab infusions, every 8 weeks as a day patient in hospital. This caused enormous weight gain and I have just recently gone back onto mtx 25 mg injections which is working okay.
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