Adalimumab biosimilar
Common Questions and Answers about Adalimumab biosimilar
humira
As there was no improvement. Doctor adviced to have Exemptia (Adalimumab) injection. 4 injections (40mg 8ml) was given. Next day he was having stomach pain, tight and rigid stomach, and fast breathing. He was immediately admitted in the nearby hospital and doctor found he was suffering from megacolon (toxic colon). After taking x-ray and CT scan, it was found that there was perforation in his stomach.
Yesterday my rheumatologist has finally decided to give me something other than anti-inflammatories and anti-depressants for my list of symptoms which he has decided are due to either Ankylosing Spondylitis, Psoriatic Arthritis (Palindromic Rheumatism was mentioned too) or possibly all of the above, with a side order of Fibromyalgia. Just wondering if anyone here has taken Humira (Adalimumab) as I've read about it and am freaking out a bit!
Yes, Humira will indirectly help in controlling diarrhea and digestion. Let me explain this. Humira or adalimumab is a biological response modifier and tumor necrosis factor (TNF) blocker. Thus, in Crohn’s it will modify your body’s response to disease (bloating, tenderness, diarrhea, indigestion etc). This is because any immune mediated disease like Crohn’s produces excess of an inflammatory protein called TNF-alpha, which causes cellular damage along with pain and inflammation.
As most of us know Humira (adalimumab) reduces the effects of a substance in the body that can cause inflammation.
Common Humira side effects may include: headache; nausea;
cold symptoms such as stuffy nose, sinus pain, sneezing, sore throat;
rash; or redness, bruising, ITCHING, or swelling where the injection was given.
So what you are experiencing is not unusual - however I think you should give your MD a call as Sherry also suggested. He/she needs to know about your reaction.
While it is antihistaminics, topical and oral steroids for eczema and antifungal for fungal infection, the treatment of psoriasis that have been approved by FDA are adalimumab and Xtrac Velocity excimer laser system. Apart from that, topical medications like emollients, creams containing coal tar, dithranol, corticosteroids, fluocinonide, vitamin D3 analogues and retinoids have been routinely used.
So before using any treatment it is advisable to consult a dermatologist.
I hope it helps.
Taper off the steroids to low potency ones after consulting your dermatologist. The drugs that have been approved by FDA are adalimumab and Xtrac Velocity excimer laser system. Apart from that, topical medications like emollients, creams containing coal tar, dithranol (anthralin), corticosteroids like desoximetasone (Topicort), fluocinonide, vitamin D3 analogues (for example, calcipotriol), and retinoids have been routinely used. Phototherapy containing UV A has also been employed.
Though non steroidal anti-inflammatory agents (NSAID) and steroids are the gold standard of treatment, more emphasis should be laid on physical and occupational therapy, rest, heat pads and use of assistive devices for walking. Biological response modifiers like etanercept, leflunomide (used less often), adalimumab, or infliximab can be added in consultation with doctor.
Medicines prescribed for Crohn’s include fibre supplements, Aminosalicylates (medicines that help control mild to moderate symptoms), corticosteroids, medicines such as azathioprine or 6-mercaptopurine and biologic therapy like Infliximab and adalimumab in severe cases.
It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.
The drugs that have been approved by FDA are adalimumab and Xtrac Velocity excimer laser system. Apart from that, topical medications like emollients, creams containing coal tar, dithranol (anthralin), corticosteroids like desoximetasone (Topicort), fluocinonide, vitamin D3 analogues (for example, calcipotriol), and retinoids have been routinely used. Phototherapy containing UV A has also been employed. But it is usually seen that psoriasis can become resistant to a specific therapy.
The drugs that have been approved by FDA are adalimumab and Xtrac Velocity excimer laser system. Apart from that, topical medications like emollients, creams containing coal tar, dithranol (anthralin), corticosteroids like desoximetasone (Topicort), fluocinonide, vitamin D3 analogues (for example, calcipotriol), and retinoids have been routinely used. Phototherapy containing UV A has also been employed. But it is usually seen that psoriasis can become resistant to a specific therapy.
Drugs called TNF-inhibitors (etanercept, adalimumab, infliximab), which block an inflammatory protein, have been shown to improve the symptoms of ankylosing spondylitis.
I'm going to refer your post to the Hysterectomy Forum, there is a wonderful CL there who will be able to tell you if there is something related to that surgery that could be causing these issues. (This forum is related to pelvic organ prolapse.)
Good luck, I hope you find some relief soon.
Which is why so many of the biologic drugs used for those conditions, such as adalimumab (Humira), etanercept (Enbrel), and infliximab (Remicade) show promise for HS sufferers."
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Excerpts from "Putting Hidradenitis Suppurativa Into Remission"....
"I decided to ask Loren Cordain about HS when I interviewed him at the AHS last summer. He mentioned that he thought HS might have an autoimmune component but other than that, he didn’t have any information.
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