tysabri optic neuritis

t have a connection to the pons in the brain stem like Cranial Nerves 3-12. The optic nerves, optic tracts, optic chiasm and optic cortex are all in the cerebrum. Damage to CN3 and 6 can effect the movement of the eye or the dilation and contraction of the pupil. Problems with eye movement can cause "vision issues," but these are usually related to double vision. He may have said the you have a lesion in your brain effecting your vision.

Hi, I am new to MS, sort of. I had optic neuritis 4 years ago (Iritis). Little things since then, mostly tired all the time. I have had many MRI's each showing growth in size and number of lesions. I was finally dx Aug. 2013. I was put on Rebif for 6 months, and when I had another MRI, it showed significant growth in size and number of lesions. The only thing I really noticed was I was forgetting words and names. Very frustrating and a little embarrassing.

s not as vague as symptoms like numbness or tingling, fatigue etc about 20% of pwMS recognise ON as their first symptom that lead to being dx-ed with MS but to complicate matters not everyone who has optic neuritis will actually have or then develop MS. The average time from first symptoms to diagnosis is suppose to be around 4.6 years for the under 50, over's is 3.2 years but there is no specific expectation of time frame.

I saw an opthamologist yesterday and was told that I have optic neuritis in the right eye. My visual acuity is normal, thank goodness, so that is a good sign. However, blurriness and double vision comes and go--and has for some time. Plus, I don't see well at night. But the weird thing is, after having my eyes dilated, the pupil in my right eye remained dilated the next day. As today progressed, the pupil is coming back to normal, but is still slightly larger than the other one.

Anyone with MS ever experience complications with optic neuritis? I ask because I had what seemed to be optic neuritis several years ago, but I'm not even certain if that is what it was. Woke up one day with a huge blind spot in one eye accompanied with flashing lights and pain. Doctors confirmed I had swelling and inflammation of the optic nerve, but they didn't say anything about optic neuritis and they told me there was nothing to do about it and not sure why I was experiencing this.

Most people with optic neuritis (about 90%) experience pain when moving their eyes. This pain usually subsides after a couple of days, even if vision is still affected. Appearing Over a Couple of Days: For most people, the onset is pretty rapid, with the peak vision loss occurring within 24 to 48 hours of onset. Usually Only in One Eye: Optic neuritis can affect the vision in both eyes simultaneously, but this is extremely rare.

2) It has been my understanding from reading the medical literature (I am a physician) that, if the demyelinating lesion in MS is far enough back, that the fundoscopic exam may not reveal optic nerve pallor or other signs of optic neuritis. I have also read repeatedly that in, documented optic neuritis, the fundoscopic exam may be normal in more than 50% of MS patients. I have reported this on the forum. Am I correct?

Pain. Most people who develop optic neuritis experience eye pain that's worsened by eye movement. Pain associated with optic neuritis usually peaks within several days. Vision loss. The extent of vision loss associated with optic neuritis varies. Most people experience at least some temporary reduction in vision. If noticeable vision loss occurs, it usually develops over the course of hours or days, and may be worsened by heat or exercise. Vision loss may be permanent in some cases.

The first 5 were bumpy with 1-2 attacks per year and then I went into remission for 8.5 years. I just had a recent bout of optic neuritis and my neurologist is recommending one of ABC drugs. Is there anyone out there who is not on these drugs and managing the illness well or is it a definate that with no drugs we will all end up in a wheelchair as my neuro told me.

No one can rule out MS if the optic discs are normal. Period! Also, 64% of people who have optic neuritis have normal appearing optic discs. So, while pale discs and evidence of optic neuritis can be used to help validate a diagnosis of MS, a normal eye exam can NOT be used to rule it out. Whoever said that normal appearing optic discs rules out MS is a dodo!

diagnosis and if someone has had optic neuritis. Basically if someone has optic neuritis in the past, does that mean later in life the lesions for M.S. would only be on the brain and NOT on the spine?

I have heard Optic neuritis can lead to MS. Would Ocular herpes be considered Optic neuritis ?

s an excellent web site about optic neuritis that tells you everything you want to know about optic neuritis (be sure to scroll down to see the entire page: http://www.emedicine.com/oph/topic186.

I recently went to an Opthalmologist because i was experiencing bad eye pressure, weird tingling in my head, and eye blurriness. The dr said that I had bilateral optic neuritis and told me that i need an mri.... I went and got an mri and everything came back ok. They were worried about the possibility of MS. I have gone through sooo many tests, blood work, Lumbar Puncture and all the tests came back ok. No one can tell me what is causing the Bilateral optic neuritis.

Optic neuritis is one for of optic neuropathy (which means literally a sick optic nerve). Most cases of optic neuritis including MS do get better, many clear completely. Optic neuropathys due to glaucoma, compressive neuropathies (trauma, tumors), ischemic neuropathies (example temporal arteritis) often do not improve or get worse. I do not claim to be an expert on neurophysiologic testing of the eye but I would never make a diagnosis based in just changes in amplitude and latency of the test.

Is your doctor aware of the Optic Neuritis Treatment Trial. Often, optic neuritis is treated with a protocol of intravenous, then oral steroids. I'm confused why this has not at least been discussed with you. Nerve conduction is slower in higher temperatures, especially with optic neuritis. The higher temperatures don't worsen the MS - they can just bring out the worst in your symtoms sometimes - particularly with vision.

Optic neuritis is inflammation of the optic nerve anyplace between inside the eye and where the optic nerve ends in the brain. Retrobulbar neuritis is a for of ON where the inflammation is behind the eye and can't usually be seen when the MD looks in the eye. Read this excellent reference: http://www.emedicine.com/Radio/topic488.

You have electrodes in the back of your head and they measure the latency from your eye to the optic cortex of the brain. It is very sensitive for detecting Optic Neuritis.

The Optic Neuritis is the inflammation of the Optic Nerve. The typical cause for the inflammation is demyelination of the nerve. The after effect can last for months or be permanent. While we say "Optic Nerve," that actually refers to potions of the Optic Nerves (2,) Optic Chasm (1) and Optic Tracts (2) that end in the Optic Cortex of the brain. A VEP measures the Timing form the stimulus through the eye to the Optic Cortex. Anywhere along the path damage can occur.

In many cases of optic neuritis - inflammation from an attack on the myelin of the otpic nerve - the optic disc becomes pale. This paleness represents loss of nerve fibers within the optic nerve. It is one of the classic signs of optic neuritis. HOWEVER.....(you knew this was coming, didn't you?) in people with confirmed optic neuritis the disc will show changes ONLY 60% OF THE TIME OR LESS. That means that almost two thirds of people with known optic neuritis will NOT show changes.

Mainly I want to answer your question about whether the Ophthalmologist would always see evidence of optic neuritis. The answer is a definite no, at least not on examing the optic nerve. In 50% or more of cases the optic nerve looks normal in the presence of confirmed optic neuritis. This is because the demyelinating lesion is too far back on the optic nerve to show signs at the eye itself.

Dear Dr. Zuhdi, I think I can explain what is going on with your son. First, let me say that there is a good chance his vision will return to normal in a few months at most. What has probably happened is, the trauma that took place has done something to his optic nerve, which transmits information from the eye and to the occipital cortex of the brain. This can be called either optic neuritis or another condition called traumatic optic neuropathy.

Hi, Swollen optic nerve is known as optic disc edema. The common causes are optic neuritis, papilledema, anterior ischemic optic neuropathy. The treatment will depend upon the cause. I would suggest you to consult an ophthalmologist at your earliest.

Just a heads up. That is a demonstration of the Afferent Pupil defect. Not everyone with Optic Neuritis gets this. One of the big issues with Optic Neuritis is that 50-60% of people with an abnormal VEP will have no "anterior signs." They will complain of decreased vision, color changes, possibly diplopia, etc. but may have a normal exam and normal pupillary reflex.

Tysabri optic neuritis

Common Questions and Answers about Tysabri optic neuritis

tysabri