There is not definitive medical treatment for depersonalization
and derealization however antidepressants such as SSRIs (prozac,
lexapro, celexa, paxil, zoloft etc) and benzodiazepines (used for anxiety, such as valium, klonopin, ativan) have been used with some success in some patients. Counseling by a psychologist may also be helpful in some cases.