Tarceva and avastin lung cancer
Common Questions and Answers about Tarceva and avastin lung cancer
tarceva
We are 28 Months down the road and have been through Tarceva, carboplatin/paclitaxel/avastin, a phase II trial and are setting off on the next stage. I think there are too many variables to give one answer, but the thing that has made a difference is good morale and a willingness to wage absolute war with the disease. We are not done yet and are going tomorrow to choose from an array of options, some of whom were not available 6 months ago.
We asked about radiation/chemo/surgery and she said this was not a option. But I read on here about others who had Lung cancer that went to the Adrenal Gland and brain etc. and they had surgery or radiation? Also do you know of a Doctor up here near Buffalo New York other than Roswell Hospital that we could go for a second opinion.? Thanks for your help!
In 2005, he had Tarceva. In 2008 they discovered metastasis to the liver (3 lesions) and he underwent chemo again (I think Avastin) and he finished the treatment in March. The doctor said the tumors in both the lungs and liver were smaller.
For the past 3 weeks he´s been vomiting, but sporadically. There is no pattern. It doesn´t matter if he eats lightly or heavily. Some days he vomits once, some days nothing.
He went to see a Gastroenterologist. They did a sonogram...
Asians, women, non-smokers, and those with adenocarcinoma histology. This drug still has been found to benefit males, smokers, and those with squamous cell histology, but to a lesser extent.
Edema (fluid accumulation in any body part, resulting in swelling) has been reported as an adverse event in 37% of pancreatic cancer patients taking Tarceva, although this side effect has not been reported in lung cancer cases.
However, the type of edema associated with Tarceva use is either generalized or involves a swelling of both legs. Swelling in only one leg may not be due to this drug. Unilateral leg swelling may be due to a local infection (cellulitis) in that area.
I was then diagnoised with NSCC of the other lung, they found a tumor on the Junction of the upper and lower lobe of the left lung. At the time of the procedure it messured 1.3 cm at the time of being placed on Tarceva the measurment 1.9 cm with in three wks after surgery in April.
Placed on Tarceva the first of May and No incress in growth...Doctors say Stable Remission...Now I have been told that I have a Mass on the back side of my thyroid gland on the left side.
Hello I am a caretaker. My client was diagnose with lung cancer stage IV. It has already spread to the spine, both lungs and the lymph system. Doctors triede Tarceva for 3 weeks but her body had a very bad reaction. For the spine they did radiotherapy. But since she was diagnose 3 months ago she has lost aalmost her voice. she is using oxygen for the major part of the day but doctors don't wan't to talk about time. no more medes will be given and she was reffer to hospice....
If the patient improves with the radiation, or maintains adequate strength or performance status(sufficient strength is usually defined as able to remain up and about at least half of the waking hours), you may wish to discuss other options aside from tarceva - such as the original plan of cisplatin and etoposide. This is because there is a known benefit for these drugs in terms of survival when used as first option among good performance status patients.
He has been through several chemo and radiation treatments and is now starting on Tarceva. It has been a long road so far and he has his good days and bad days. I don't think there's any way even the doctors can tell us how much time they have left specifically. His doctor said it could be a year, 5 or even 10, but of course we are all hoping and praying for at least 20 more with him.
Hi There...
I have had a upper right lobectomy on Sept 14 2001.Stage 1A BAC lung cancer...no chemo or no radiation..clear margins and no lymph node involvement.. ..it's been a little over five years now. cancer free. PRAISE GOD...and thou I realize that 5 yrs is maybe the magic number for most lung cancer survivor's...is it also meant for BAC Lung Cancer...I have heard not so....
Thank you for any information you can give me....
for patients with late-stage colorectal cancer or late-stage non-small-cell lung cancer but many doctors use it to treat breast cancer. Common side effects of this drug are: high blood pressure, Gastrointestinal perforation, hemorrhage, arterial thromboembolism.
(http://www.mims.com/Page.aspx?menuid=mng&name=Avastin+vial&h=avastin)
I hope this helps. Take care and keep us posted.
Right now, doctor changed the chemo to Lipo-Dox, and will continue with it for a while. Avastin and Docetaxel do not work well for her. Right now doctor found that the cancer spread to her right lung already (which did not appear in the passed 6 month).
Anyway, Thank you again for your information and suggestion and goodwill. I will pass it to my mom, and wish all the best for you and your team, your family, and all love one.
In lung cancer, there are assays for quantitative testing of epidermal growth factor receptors (EGFR), which confers sensitivity to some drugs used in lung cancer like Iressa or Tarceva. The cost of testing can range from a few hundred dollars (e.g. ER/ PR assays) to around 3800 dollars for the Oncotype DX test.
I was orginally diagnosed with malignant pleural effusion IIIb (a form of lung cancer) 4 years ago , I had numerous CAT scans. Even one of March of last year showed no tumor activity. In June, my abdomin began to swell; a new CAT revealed a tumors on the ovary - Ovarian Cancer IV. I was operated on in July and evrything was removed and I spent 5 weeks in the hospital. No one thought I wouls make it to Christmas I was so weak.
After a two year+ remission was treated with doxli for a year+ then carbo again (now allergic) Gemzar (didn’t work) back to Taxol (worked like a charm) a year later had to move on and Avastin was the ticket, stabilized for a year and then added nexavar. 6 months later rising markers dictate a change again. Please keep in mind that my CA 125 is well over 2000 and my 27-29 over 120. They have been pretty high for years now (over 1,000). The confusing part is that my PtCts have been clean.
So, the plan is a 12 week course of chemotherapy and if it works well for me the possibility of radiotherapy later on and Tarceva too. So now I have to chose which drugs to go with and maybe I'm wrong but I'm thinking that if the Cisplatin works better in reducing the tumors I may have a better chance of the radiotherapy also working more effectively too.
inoperable; no relevant mutations. He had undergone radiation to lung and several rounds of chemo (Carboplatin, Taxotere, Cisplatin, Gemzar). He also had surgery to remove one brain met (January 2014) and one kidney (May 2014)… CT scan in December showed no mets outside lung and lymph nodes….
He started Tarceva this January but it seems it did not work as the cancer spread to brain….
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