Take Calcium or Iron supplements and their food/drinks, and soy products four to 12 hours of your synthroid
for they interfere with
aborsption, as well as the same with
Aspirin and equivalent. Aspirin and other salicylate drugs (Pain killers) may increase the effectiveness of your thyroid hormone replacement by releasing more drug into the blood from body storage sites.
As an added after thought, Thyroid medication can be stimulating, so it is best to take it early on in the AM.