In my opinion, dosing once per day, always in the morning, is critical to success. Yes,
Suboxone alone will block most of the desire
for opiates, but when used properly there is so much more that can be done; by dosing once per day we try to extinguish the using behavior. Most people starting Suboxone will ignore the initial recommendations and take it twice per day; I work very hard to get patients to take it ONCE, and to NEVER take it in response to feeling the 'need' for it.