Oxycodone and liver

Common Questions and Answers about Oxycodone and liver

oxycontin

It is therefore advisable that opioids should be administered cautiously and may be given at reduced dosages in patients with liver disease. If possible an alternative medicine may be prescribed. I hope you find this information useful. Do keep us posted. Good luck!
Too much tylenol can cause liver damage and even liver failure. Initially, the maximum safe dose put out by the pharmaceutical company was 4,000 mg per day; however, there is a new lower maximum recently released that states 2,600 mg per day is the maximum. The maximum single dose of tylenol that can be taken safely is 1,000 mg. The oxycodone-acetaminophen that you are taking contains in each pill 5 mg of oxycodone and 325 mg of acetaminophen (aka tylenol).
Sometimes I get a minor discomfort in the area of my liver, but no other symptoms. I do know the liver regenerates all the time and will start as soon as the substance is removed. I am trying to coordinate doing an outpatient detox within the nest few weeks but have obstacles in my way. I have a 2 year old I need to find care for from like 10a to 8 pm for 2 days. My hubby does not know but will tell him ONLY if I have too. I cannot tell my parents or MIL. Thanks for letting me vent.
low dose formulations of oxycodone such as percocet(oxycodone/acetiminophen(tylenol)) or percodan(oxycodone/aspirin) which is most commonly given in 5mg or 10 mg tablets is usually given after certain surgeries and for people in severe pain. both oxycontin and percocet abuse has grown in popularity immensely in the past 10 years. its extremely drastic how fast it has arose to being a DOC for people. and the wd's are the same as other opiates of its kind like heroin or dilaudid.
Can anyone give me some advice as to what to expect? I really want to stop and have deleted and blocked the phone numbers from all the bad influences. Also, can I expect to have some liver damage? I know this is a lot but any feedback would be appreciated. Thanks!
Hi, I am post op cranial aneurysm surgery in 2002 and hve had chronic H/A's since before the surgery. I also have rheumatoid arthritis: 5 years now. I have had a liver injury(which was from taking the antitdepressant Serzone) which has been settled now. I have been on and off medication since then. I am right now tolerant built up to Oxycodone 30 mgs. 8 x daily. I can't take insaids My doctor prints out reills for me on this so I can get them filled when I need to.
I stopped taking all medications then added them back one by one. Oxycodone is the culprit. I was surprised because I took it off and on often before back surgey, then intensively after surgery. I haven't taken it for months, but the other med I was on caused stomach problems- so back to oxycodone I went. While looking for info about this strange new reaction to a drug I had taken before without problems, I found the following info on MedicineNet.
Hi Sue what is Oxycodone? Do you get it from the doctors? I too have chronic gastritis and it is agony on flare ups. I take Pantoprazole,Gaviscon and I can take Sucralfate. They don,t do much though. Its really awful isn,t it I hope you find relief for your pain too.
My husband is one as well, he is on pain management and his liver is fine I am sure other people will come along and help out, there are many nice people here on this site
One thing I have not see anyone say about the differences in hydrocodone and oxycodone is that hydrocodone is schedule III while oxycodone is a scheduled II......
The pain subsided afterwards, and they did an ultrasound on my liver, kidneys, and bladder. My left kidney showed some inflammation, along with a small portion of the connected ureter, but could not see any kidney stones. The resident OB told us it's most likely a kidney stone and prescribed me with 2 325mg of percocet every 4 hours for the pain and gave me a strainer for the bathroom to catch the stone, and released me Friday morning.
Because saying Percocet is the only safe drug for your fetus makes no sense to me at all Percocet is still an opiate and is infact the exact same as the 30mg oxycodone you have been taking. The only difference is that the Percocet is a lower dose of oxycodone and it contains Tylenol but its the same narcotic in both meds and is no different except I would think Percocet would be worse because of the Tylenol which can be DEVESTATING to the liver.
I have been on heavy doses of prescribed oxycodone for car accident and multiple neck surgeries for a year half now. Of course I started taking it for the pain but you all know how the story goes. So I decided enough is enough and started rapid taper 3 days ago. I went from my usual 135m a day down to 80 the next, yesterday I took 40m and today I am at 20mg. Needless to say I feel like poop but I am determined to do this. Any helpful words or advice would be appreciated!!!
If you can move around and do anything, the physical activity gets the natural endorphins in your brain going. And the hot baths and showers help too. You should start feeling better in the next day or two. And keep posting!
Hello Supportive and Helpful Group! I am on Day 4 already. Between yesterday and today there is no appreciable difference in terms of withdrawal symptoms. I am freezing, fairly tired, in a bit of pain, have sporadic moments of restless arms and legs, and I have that incredibly yucky taste in my mouth and sleep is very elusive. Today I also developed pretty awful stomach pains and diarrhea (yuck) .
The firms are producing and shipping as product becomes available and it is currently estimated that return to normal supply levels may occur in approximately 2 months. For the other forms of oxycodone, such as extended release oxycodone tablets and combination oxycodone products, we have not received reports of shortages.
As for non narcotic meds, that is a crap shoot, ive tried every possible NSAID out there with not success, besides toradol, which i got a shot of at the hospital, and apparently you cannot take that more than once every few months or your liver and kidneys will fail.
I have been on 6-7 oxycodone daily for the last four months. Prior to that I was on Norco 10/325 for 18 months. Is it safe for me to quit cold turkey at home? I am in good general health. I have clonodine, clonazepam and neurontin to help me along with Flexeril. Is it safe to stop or do I have to taper? I have been prescribed these drugs for severe, unrelenting pain in both of my feet. I have been to neurologists, rheumatogists, podiatrists, to no avail.
ACTIC (FENTAYL LOLLIPOPS) AND THEN SWITCHED TO THE FENTAYL PATCHES, I SWITHCED DOCTORS AND WAS TAKEN OFF FENTAYL THEN LOST MY INSURANCE AND PUT ON METHADONE AND OXYCODONE, I AGAIN SWITCHED DOCTORS AND CURRENTLY ON OXYCADONE 30MG 8 A DAY AS WELL AS XANAX WHICH I AM BEING TAPPERED OFF OF NOW, THEN MY OB WANTS TO TAPPER THE OXYCODONE I DON'T WANT TO HURT MY BABY IN NO WAY BUT AT THE SAME TIME I'M WONDERING WHAT KIND OF SEVERE PAIN I WILL BE IN WHEN I AM OFF OF THE PAIN MEDS, BUT I DON'T WANT MY B
With the controlled release of the med I'm taking now, things seem to be on an even keel compared to the abrupt ups and downs of the shorter acting narcotics like hydrocodone and oxycodone. As I've said time and again, all I want is a state of equilibrium in my life where everything seems to be safe and secure....and pain free! I suppose that's a lot to ask for as a human being? Somebody said above that they went fifteen years in hell before discovering a med that offered some relief.
You are only allowed 4000 mg of acetometaphine per 24 hours and if he was taking 10/500 or 10/325 and taking them ten times a day then is getting a lot of Tylenol. This over time maxing out the limit will wear on the liver. Also, with a tolerance that high, will most likely have a pretty rough first detox. I would definitely recomend saying something to them and try to convince them to get help. A habbit like that is either expensive, deadly, and or torture to loved ones around him.
It was not till on day the college kids from church prayed for me and we threw 14 bottles of prescriptions into the trash and my headaches were gone forever. My liver is in excellent health and my recent blood work shows i am fit as a fiddle... I would get a Bible and turn to the Gospel of John. I had a cocaine addition 19 years ago and rehab centers did nothing. The only think that helped was accepting what Jesus did for me on the cross and living for Him.
The question was focused on weather oxycodone (or hydrocodone for that matter) alone is toxic to the liver and cause toxic hepatitis. My doctors have all said very low risk IF NOT COMBINED WITH APAP or ibuprofen. I only clarified the "combo" discussion. Acute pain is treated regularily with oxycodone and does not automaticaly lead to addiction, particularily when used for severe pain management.
So, the doctors I was seeing switched me to 15mg. Oxycodone and then the Fentyle patched (150mcg.) None of that worked for a long enough time, and, like you, my depression was relieved when I took pain meds. Alway Happy and talkative. Smiles and jokes. But, when the pills wore off, man, what a come-down. I wanted to jump out a window. Valium made me even more depressed and antidepressants just put me to sleep and nothing worked. Nothing, until a big dose of pain meds. Then, I found Oxycontin.
so I called in to get Oxycodone, then, I got my new script, and magically I was cured and took both! It was strange. then I detoxed and it was hell. day 30 of no pills. YES!
Why would a physician give Lorazapam and Oxycodone to a patient who has severe liver damage and also has a history as a youth to drug addiction, and recent serious alcohol addiction that caused the liver damage in the first place??
Using it over a span of time regularly acetaminophen can cause damage to your liver and kidney even at recommended doses. So many people use it daily but it's really a OTC that's supposed to be used for short spans of time or ever so often when it's really needed. I'm not sure how long it would take to cause failure if it's taken at prescribed doses, probably quite a while. But the real danger is that there's no comming back from acetaminophen caused liver or kidney function or decline.
I have seen a Doctor done some test the doctor says that my liver is enlarged and come back in a year and then we will check its size again. I do not feel that comeing back in a year really has helped me with my symptems nor has it helped me to figure out what is really going on in my body. I am a relitively healthy person, I DO NOT drink nor do drugs and I beleave I eat fearly well, light foods and my weight is average I have good muscle tone cause i do exercise.
Liver injury (hepatitis) secondary to paracetamol is usually seen in people with pre-existing liver disease or in alcoholics. It is usually clinically apparent with jaundice and elevated liver enzymes. Hope that this information helps and hope that you will get better soon. Thank you for using MedHelp's "Ask an Expert" Service, where we feature some of world's renowned medical experts in their fields.
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