neupogen vs leukine

Does your trial give your doctor leeway to determine what comes first, the neupogen or the dosage reduction? If yes, you can ask your doctor to go with the neupogen first, stating you don't want a dosage reduction. Adherence to dosages in the first 12 weeks are particularly important. If the trial does not allow your doctor that leeway and it strictly requires dosage reduction at 750 ANC and neupogen at 500 ANC, you'll have to follow trial mandates.

Have been trying to cost what a ceiling amount might be for a 12 week period to see if I can organise sufficient funds. Neupogen in prepared syringes are sold in packs of 10 - $1504 for 3000mcg/.5ml shots and $2407 for 480mcg/.5ml shots. I realise that amount required is case dependant but wouldnt mind any info which might assist me to at least get some idea of the range which may generally apply.

I would want to know what difference the 2 wk. VS 3 wk. Chemo would make medically for me before I made a final decision. If your Oncologist approves then the blood testing every week sounds quite reasonable. Thinking about the most severe of all side effects seems a bit negative to me as that doesn't happen often. If you feel that you need a second opinion from another Oncologist you are certainly entitled to one. Regards .....

It is a known fact that HCV therapy(specifically INF. can reduce neutrophil counts (neutropenia) in patients quite often. However it seems clear from the thousands that have been involved in the studies below that there seems to be" little" if "none" at all correlation between low neuts(ANC) and increased incidence of infection. The labeling on INF.

Do any of you have information about any long term side effects if you had Neupogen for 40 weeks?

I just read that a lot of people try NOT to take Neupogen unless it is a necessity due to sx. I am on Neupogen and I take it 3 times a week and have been taking it for 8 mos. now. Does anyone know exactly why people/anyone would want to NOT take Neupogen? Your answers may provide some insight for me and my sx's.

The Hematologist said he was going to start him on Neupogen is anyone else taking this and is it working for them. He also said that he may need a transfusion , which is freaking my husband out because that is how we suspect he contracted the Hep c orignally (back in the 80s). I told him that they screen the blood much differently now then they did back then , but he is still freaking out. Anyone who is taling Neupogen please let me know if it is helping.

low blood count started neupogen injections to build up white blood cell count so I can have chemotherapy, can I drink beer with this?

Just got the call this morning that my doctor wants to put me on Neupogen for 4 weeks because my white blood cells are so low. I'm so disappointed, I really wanted to be done shooting into myself!! Anyone else out there on this drug? I don't know a thing about it.

So the doc finally agreed to a neupogen shot, after many delayed shots of pegasys. I was supposed to do a shot tuesday, however got bloodwork done today and anc is 620, Doc says to take neupogen tonight (I did, the neupogen is 300mcg, im ~130lbs) and get more bloodwork done on thursday, and then he'll call friday with whether or not to take the shot or not. So here I am, waiting, again. Arggg!

I am supposed to receive Neupogen tomorrow. Did my peg shot this morning. I'm sure I will get instructions with the med but it's good to get some input from those who are currently treating with it. Are we supposed to wait 24 hrs after the peg shot to inject Neup? Should I inject more slowly than I do with Peg? Docs office told me to reduce peg today to 135 mcg but I didn't (me not listen - what a revelation) because I knew I was getting the Neup tomorrow.

HI ALL,HOPING U CAN HELP ME OUT WITH WHERE TO FIND/BUY MEDS LIKE NEUPOGEN FOR LOW WBC,IV HAD LOTS OF TROUBLE WITH LOW WBC AND MY DOC SAID AUSTRALIA HAS NOT APPROVED IT. IM AN AUSSIE AND HOPING SOME1 KNOWS OF WHERE TO GET THIS STUFF,OR ANYTHING THAT WILL HELP.IV HAD MY DOSE LOWERED AND IT SHATTERS ME COS MY CHANCES WOULD BE MUCH HIGHER WITH FULL DOSE OF INTERFERON. I DONT CARE WHAT IT COSTS I JUST WANT TO BRING MY WBC UP COS IV HAD SO MANY INFECTIONS AND FLUES ETC.

From the two trials cited in Can-do's link: Using weight dosed Peg-Intron and weight dosed riba - "In an analysis of all RVR patients treated per protocol, 91% of those who received 14 weeks of therapy achieved SVR, compared with 95% of those treated for 24 weeks. The difference of 4% fell well within the pre-determined 10% margin needed to show inferiority, allowing the researchers to conclude that 14 week treatment was non-inferior to 24 weeks..........

http://pi.amgen.com/united_states/neupogen/neupogen_ppi_pt_english.pdf Among other things: "Serious Allergic Reactions. NEUPOGEN can cause serious allergic reactions. These reactions can cause a rash over the whole body, shortness of breath, wheezing, dizziness, swelling around the mouth or eyes, fast pulse, and sweating. If you or your child starts to have any of these symptoms, stop using NEUPOGEN and call your doctor or seek emergency care right away.

It has been one week since the last treatment and my WBC count is 900 (ninehundred) Can they now give me a neupogen shot. I would think they should take a count daily. and give Neupogen if it till it corrects.

Anyone get any help with bone pain and seems like a migraine after neupogen ? I am on my second shot and it's 4:30 am and I have been up all nite with a horriable headache and severe nausea. Will call docs today and ask for something.

Next time I try treatment I'm going to suggest to my doctor to prescribe neupogen and procrit before I start to get the counts up. Mine have always dropped into the low range. I found especially the neupogen made me feel rough after I was already well into treatment and didn't do a whole lot. Why don't doctors prescribe it before treatment? Would there be a downside to that?

How much neupogen are you guys taking per shot.

My hematologist has explained that no one knows the reason that neupogen causes bone pain in some people. It has been said that neupogen stimulates the bone marrow and that can cause the marrow to push against the inside of the long bones and cause some pain. But your guess is as good as anyones as to why it happens. The good news is that most people get used to the neupogen and it stops hurting.

Neupogen vs leukine

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