Metformin long term side effects

Common Questions and Answers about Metformin long term side effects

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Yes, one nasty side effect of Metformin is nausea. He should have been aware of this from reading the pharmaceutical paperwork that accompanied the Metformin bottle, or by his Pharmacist. Keep in mind, not everyone can tolerate the same medications. What he needs to do is notify his doctor asap as there are other oral diabetes medications that can be Rx'd.
Bravo, Dave. :) The long-term side-effects of treatment (as well as the side-effects of long term treatment) are thoughts that run around in my head a lot, sure. I've watched my husband endure 128 weeks of interferon, and though it's obvious to both of us he's not the same physically, we can only figure things from an *anecdotal* standpoint -- how objective can we be without a *control* situation, after all?
I did have a doctor tell me once, during a post treatment problem I was experiencing, that, there's a lot that's not known about the long term effects of these meds. I appreciated his honesty with me. I still treated a whole bunch of times. I think everybody has to make the decision to treat, or not to treat based on their individual situation, their amount of damage, their doctor's advice, etc. Nobody is definitely 100% right with either argument, pro or con.
I have lost 70ls in 8 monthIs. I have no side effects but weight loss... Is there any long term side effects I should worry about?
Of the many years hCG has been around there have been very few true long lasting negative side effects reported. And actually, none have been reported in decades that have been attributed specifically to the low dose hCG used in the protocol. Some of the things reported in this thread can be alleviated with increased water intake. Side note: drinking a few ozs of pure aloe vera juice/gel with each meal helps with bowel movements better than colace or other medications perscribed.
So far I have experienced only very mild side effects (vomiting once). One thing I am trying to figure out is if the metformin is the reason I feel so drained. I have zero energy. I've never been the most energetic person but now I have so little energy I find myself spending less time shopping and going to church. I hear the met can cause a B12 deficiency, so maybe thats what it is. The pharmacist tells me its hard to absorb the vitamin so its kind of pointless to take them.
Metformin is usually instructed to be taken with food or milk due to the GI side effects of diarrhea, nausea, vomiting, abdominal bloating....and yes, taste perversion. Your Dr. may have first ordered the medication in 4 seperate doses due to the above, however, I have not seen that done before, but doesn't mean it is wrong.
I was just curious to see if any of you have already wrapped up your 12 weeks of Incivek. If so, did your side effects get any better? Since I have to treat 48 weeks I have been counting down the days until the Incivek is over and hoping that things will get a little easier once this part is over. Thanks!
I took it for over a year and I was finally ovulating and having regular menstrual cycles. I never had any side effects from it other than the usual stomach discomfort/potty problems...I was able to conceive and I gave birth to a beautiful healthy baby girl 08/29/08. Following my postpartum term, I had two periods and nothing since then. My doc says I can go back on Met if I want to (but I don't have to have a period). Is this true? Would it be safe to go without any medical treatment for PCOS?
The observation that metformin was associated with an improved rate of RVR but had no impact on virologic response at the later time points after Week 4 may suggest that improving insulin sensitivity allows the intracellular immune system to clear the virus in a subset of patients over the short term, but without any long-term benefits, raising the suspicion that there may be extrahepatic reservoirs of infection that may explain relapse in some patients.
My doctor thought it was enviormental (exercise, stress...etc) as I just started to go do body pump right around that time. Every cycle before that was 30-31 days to the day!! So we will see.....
In light of your study, I would aquiese, and say let's think short term only.. I would not consider it a long term solution, but to be honest I was thinking for myself of a short stint on it as a preventative to relapse. Short term, to correct Nash and/or IR until you could reeducate people might be a good alternative. Why because they don't have to start injections and (and my doc and I have discussed this) they should make classes mandatory for prediebetics.
I have had 5 miscarriages and 1 ectopic. I too was diagnosed with PCOS after other tests were done. I was on Metformin and Clomid. On the 2nd round of Clomid, I became pregnant. I have a 4yr old son and also a 20 month old. I only used the clomid and metformin for my son. The doctor said I would need the medicine to get pregnant again. Not so!!! God blessed me with a beautiful little girl also. Keep all in prayer. Remember even though we do not understand, He does!!!
Unlikely to have long-term side effects from the recent toxicity. There is no data to support removing the thyroid -- there is data to support optimizing thyroid-hormone replacement in terms of fertility. The cytomel dose I use is typically 5-10mcg in am and 2-3pm in combination with some synthroid in the am.
Obviously, you want to be on the prednisone for as short a time as possible to avoid long term side effects. However, NOT being on it is sometimes not an option. Everyone is different and can/will react to medications differently - and the side effects that one person experiences may not affect someone else with the same medication and dosage. So, unfortunately, it' simpossible for someone to tell you how long you can be on th eprednisone before side effects starting taking their toll.
com though obviously for type 1 insulin should not be used to replace insulin though can be used succesfully to complement it. Let us not forget that it the high and lows that cause diabetic side effects, if one can keep the range of BG within the aforementioned ranges, the risk of complications tend to zero or at least decrease considerably.
Hi- I am also a long term headache sufferer. I noticed that your husband is on opiate meds. I am too. I have also tried most of the migraine meds and they really did not do much for me. I do build tolerance over time and the dose needs to be upped every 3 months or so. Over a year ago I was on very doses of Hydromorphone (dilaudid) and Oxycontin. I had been on these meds for over four years and they just stopped working and the side effects were awful..
Nausea. Loss of appetite. Diarrhea. Increased abdominal gas. A metallic taste. These side effects occur 20% to 30% of the time. Side effects usually decrease over time. The dosage of metformin is usually increased gradually to prevent these possible side effects.
I HATE Mirena! I must be the "rare" side effects group expect now I'm finding tons of people like me. After insertion, I bled for the first THREE months straight, which after a month I called the doctor and he said it sometimes happens. From then on it's been an on going mess. I will have a period then not again for a month or two, then twice in one month! I have to carry supplies with me all the time.
I was all set to buy a bottle from a company that manufactures in the U.S. (as opposed to China), but the lack of long term effects stopped me. What do the experts here think about taking Berberine to stabilize blood sugar for someone who is pre-diabetic?
Hello there, The most common side effects of Metformin are abdominal or stomach discomfort, diarrhea, lower back or side pain, muscle pain etc.The common causes of sore breasts are pregnancy, premenstrual syndrome and hormonal fluctuations. Dark areas of pigmentation on the face can be due to long-term exposure to UV radiation from the sun or artificial tanning devices. These areas of dark pigmentation are called solar lentigines and are also called liver, sun or age spots.
It's common sense, really, and changes that I can keep up long term without hurting myself. The old dietition really didn't listen too well---she was very focused on having to stick to her plan for EVERYTHING and if there was one little slip, you wouldn't see results. That's just not realistic. Am I supposed to not eat at all because the meal you set out that day isn't on my schedule? No, that doesn't work. But Kendall's plan is a lot better.
The only reason to take the blood pressure medications at different times during the day are if people are having problems with their blood pressure dropping too low when taking both together (usually manifests as dizziness upon standing or changing position) or if they are having issues with blood pressure control throughout the day.
Yes metformin is not easy to take, I have a very very hard time with it, many side effects and I even took it durring my first trimester along with my bad morning sickness (never missing a dose) now that is dedication! I also worried alot about what if I could never concieve and its the worst thing you can do. Stress wont help your body ovulate or do what it needs to.
Start metformin as follows, increasing the dose if and when you have no more side effects (most people only have mild side effects that ressolve within a few days). 1. Start 1/4 tablet at night 2. Increase to 1/2 tablet at night 3. Increase to 1 tablet at night 4. Increase to 1 tab at night at 1 in morning. (increase further if need be up to Max of 2 g/day). Give the metformin 1 month trial once you are at Max dose.
I can't use Flomax or other Alpha Blockers due to side effects -- disturbed sleep. Uroxatral even cause me to sleepwalk, waking when I fell flat on my face! Separately, due to a Vitamin D deficiency, my doc put me on 50,000 units per week for 8 weeks, followed by biweekly doses. And guess what...the Vitamin D almost instantly "cured" the BPH.
That was how they specifically noted the concerns about antipsychotics not being appropriate for people with dementia. Its essential to differentiate between a short term side effect, a long term side effect and an adverse side effect which may be so clinically rare that it only happened to a few people. The adverse side effects I acquired were reported and noted in such a manner.
Hi, I recently posted about severe side effects I was experiencing with the drug Januvia , I had severe stomach pains and sore throat. My doctor has now prescribed Galvus and said they are from the same family as Januvia. Has anybody tried this drug? if so did you experience any side effects ,especially stomach pains? . It may sound stupid but I am a little scared to take Galvus after what happened before.
But, I wanted to come off it asap as the long term effects are as yet unknown. I've been taking baby aspirin - also some evidence that PCOS is related to blood clotting problems too. But its all such a new area ... I strongly recommend you find yourself a good Reproductive Endocrinologist. I've not, and fell like I'm wondering around in the dark - PCOS is little known or understood by the medical profession in the UK, from my experience. I'm on mailing lists at www.pcolist.
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