Hormone sensitive gene expression in breast tumours
Common Questions and Answers about Hormone sensitive gene expression in breast tumours
hormone
it is basically an antibody against breast cancer with an over expression of the her2/neu gene, and not all breast cancers will be her2 positive. it is a different form of treatment which is usually combined with chemotherapy. and no, i dont think the doctor will look at your nodal status, only the her2/neu.
Yeh, S F : Hong, C Y : Huang, Y L : Liu, T Y : Choo, K B : Chou, C K
Citation: Antiviral-Res. 1993 Mar; 20(3): 185-92
Abstract: It has been suggested that Phyllanthus amarus may be helpful in the treatment of hepatitis B virus infection. We studied the effect of an aqueous extract of P. amarus on the cultured hepatoma cell line HepA2. This cell line had been transfected with tandemly arranged HBV DNA and continued to synthesize and secrete both HBsAg and HBeAg. Extract of P.
There is a genetic component that results in a super-sensitive immune system. This may or may not reflect itself in your offspring. There is nothing to do about this except to eat nutritiously during pregnancy. The expression of this gene has certain advantages, however. There is a significantly lower incidence of cancer and malignancies for those with the so-called "asthma" gene. I have the study reference around somewhere.
In this study, we compared hepatic gene expression in patients prior to and during peginterferon and ribavirin therapy. In the on-treatment group, patients received either ribavirin for 72 hours prior to peginterferon alpha-2a injection or peginterferon alpha-2a for 24 hours, prior to biopsy. The patients were grouped into rapid responders (RRs) with a greater than 2-log drop and slow responders (SRs) with a less than 2-log drop in hepatitis C virus RNA by week 4.
My mother was diagnosed with breast cancer in 2008. She had a lumpectomy, (3 lymph nodes were taken out, but only one of them were positive) chemotherapy and then radiation. The tumor had both estrogen and progesteron receptors, but no HER2 receptors. Therefore, she gets hormone treatment. She started to take tamoxifen in last September. (The US before the treatment didn't show anything in the ovaries.
Did the laboratory use IHC or FISH in determining the Her2Neu expression? Form what you posted, it seems that your mother is in the early stage of breast cancer. She will benefit from either chemotherapy or hormonal therapy. She can undergo chemotherapy then hormonal therapy after she is done with her chemotherapy. Her hormone receptor status is positive. A positive hormonal status has better prognosis compared to those with negative hormone receptor status.
We confirmed these microarray data by measuring levels of NEP expression in all subjects; in addition, we found that NEP gene expression correlated inversely with proteinuria. In an additional 33 patients, glomerular and tubular NEP protein levels from renal graft biopsies were significantly higher among the 13 patients receiving cyclosporine + EC-MPS than among the 12 patients receiving cyclosporine + azathioprine or 8 patients receiving cyclosporine alone.
Most gene-expression profiling studies use tissue samples that have been flash frozen. But tissues taken in biopsies are usually chemically fixed and embedded in wax. That method preserves the tissue, making it easier for pathologists to examine, but it also renders the nucleic acids -- especially RNA -- difficult to extract.
Abstract 394
IN VIVO ORAL DOSING OF THE TLR7 AGONIST GS-9620 INDUCES AN ANTI-VIRAL GENE EXPRESSION SIGNATURE IN MURINE LIVER CONCURRENT WITH UNDETECTABLE SERUM LEVELS OF IFN-α Move back Print add this item to your Itinerary
S. Pflanz*, A. Fosdick, T. Cihlar, M. Subramanian
Gilead Sciences, Foster City, CA, USA. *stefan.
I had a small tumour in my left breast removed by lumpectomy in 2005. I was called back 2 weeks later as the Surgeon wished to do a wide excision as they had discovered that part of the tumour was a benign Phyllodes tumour. This year it came back. It grew very rapidly and had blood filled cysts around it. I haemmorhaged 3 times when it burst through the skin before surgery could take place. I was extremely low in Haemoglobin, with a count of 4.2.
It occurs when the thyroid gland makes too much of the hormone thyroxine. Overproduction of thyroxine increases the body’s metabolism and results in the lower white blood cell count. There are a number of diseases, disorders and medications that cause hyperthyroidism."
Since you have Hashimoto's Thyroiditis, it would be very unusual for you to be hyperthyroid, except in the case of having nodules on your thyroid related to the Hashi's.
Dear Kelly, Male breast cancer is rare, but one out of every 150 cases of breast cancer involves a man, usually in men over 60 years old. Treatment of male breast cancer uses the same modalities as are used to treat females with breast cancer, these may include use of surgery, radiation therapy, hormone therapy, biologic therapy and/or chemotherapy.
Gynecomastia is the development of abnormally large mammary glands in males resulting in breast enlargement. the breast development shrinks or disappears within a couple of years In adolescent boys the condition is often a source of distress. The causes of common gynecomastia remain uncertain, although it has generally been attributed to an imbalance of sex hormones or the tissue responsiveness to them. Imaging by X-rays or ultrasound is needed to confirm the diagnosis.
Thanks for the info, for I went on his website and mostly everything on there has to do with breast & ovarian cancer in regards to the BRCA gene. I could not find anything in regards to oral contraceptive use over a long period of time and links to breast cancer.
I do agree that there are good and bad.
APOE comes in several different forms, or alleles . One of the tests is - NEURAL THREAD PROTEIN GENE EXPRESSION IN DETECTION OF ALZHEIMER'S DISEASE. Please consult a gene specialist for the testing . Hope this helps you . Take care and regards !
I had a radical hysterectomy followed by chemotherapy for ovarian cancer in '07. I have had a terrible time losing weight, I cry easily, I have hot flashes, and insomnia. I cannot take HRT due to my cancer and family history of breast cancer.
Are there any natural products I can use to help any of these symptoms? Will soy milk be of any help or am I putting myself at risk of breast cancer.
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