Clopidogrel vs aspirin

Common Questions and Answers about Clopidogrel vs aspirin

plavix

With one stent--otherwise very fit--is it OK to replace plavix/clopidogrel by Nattokinase?
After six years post MI and ef varying between 25-35%, my cardiologist now feels that I should shift from aspirin(150)+clopidogrel (75) to warfarin. Two years back he did tell me that he is double minded on whether to put me on warfarin. But this time he appears to be very sure and has insisted me to go for warfarin. His justification is "that is what literature says". I have no AF or valve problem.
The recommended treatment for DES implants is dual therapy of aspirin and plavix up to a year. Combining plavix and aspirin increases the risk of bleeding vs. aspirin alone in patients treated for more than a brief period of time. That is the regimen followed for my DES implant. f you are in this category a prior MI and unstable angina:" In the CAPRIE trial, clopidogrel (plavix) was equivalent to aspirin for patients with a recent (but not acute) MI.
The most widely studied and prescribed antiplatelet agent for the prevention of stroke and other serious vascular events among high vascular risk patients is aspirin. I take aspirin daily prior to CHF.. Plavix and aspirin for preventing stroke and other serious vascular events in high vascular risk patients. Up to one year after a stent implant, plavix and aspirin are the recommended protocol as statistics have shown a high risk for clot.
If there is a contraindication to the use of coumadin, some neurologists may opt to use a medication like aspirin or clopidogrel. Occasionally, the dissection is repaired endovascularly (i.e. during the angiogram) although this, too is not without risk and is often not optimal for the patient. After this long-winded answer, my recommendation for you is that you see a good neurologist at a larger academic hospital.
Almost all patients do just fine as long as they take the required aspirin and clopidogrel (or an alternate drug depending on what your cardiologist chose). The risk of stent fracture is exceedingly rare, particularly in the heart arteries. I understand that you're concerned that the stent looks like it's placed "at a bend". This is how the right coronary artery appears on angiogram in every patient, so that is how it is usually drawn out as well.
At 18-month follow-up, there was no difference between patients with a drug-eluting or bare-metal stent in cumulative rates of death or myocardial infarction (MI). However, after clopidogrel discontinuation patients receiving drug-eluting vs bare-metal stents experienced higher rates of death and MI (4.9% vs 1.3%, respectively). These results have created uncertainty regarding the minimal necessary duration of antiplatelet therapy after drug-eluting stent implantation.
The clinically important adverse reactions observed in trials comparing Plavix plus aspirin to placebo plus aspirin and trials comparing Plavix alone to aspirin alone are discussed below. Bleeding CURE In CURE, Plavix use with aspirin was associated with an increase in major bleeding (primarily gastrointestinal and at puncture sites) compared to placebo with aspirin. The incidence of intracranial hemorrhage (0.1%) and fatal bleeding (0.2%) were the same in both groups.
She was asked to undergo an Angioplasty with 2 stents to be put in but she was adamant that she did not want it as she preferred to take the route of medication and she is too weak to undergo another procedure. She was given Ecosprin 150mg Atorvstatin 40mg and Clopidogrel 75mg along with the Beta and calcium blocker ( Amlez) that she used to take and some antacid and tonics. She also take Stugeron for her chronic dizziness.
A recent trial government trials that shows after clopidogrel (plavix) discontinuation patients receiving drug-eluting vs bare-metal stents experienced higher rates of death and MI (4.9% vs 1.3%, respectively). These results have created uncertainty regarding the minimal necessary duration of antiplatelet therapy after drug-eluting stent implantation.
I again had an episode at 7 in the morning 3 weeks after the first episode and it subsided in 10 minutes.It was then that my doctor told me to start low dose aspirin and clopidogrel(75+75) and keep a pill(Flecainide 50 mg) in my pocket in case the arrythmia lasts for an hour or so.I thought I would do some breathing exercises to maybe decrease the frequency of this problem but after doing deep breathing i had a minute of AF which subsided on its own.
I have been told that the INR safe range is b/w 2-3 for patients on triple anti-thrombotic therapy of 75mg clopidogrel, 80mg asprin , and warfarin - 10 years after aortic valve replacement. However, it has also been mentioned that an INR of 1.5 - 2 is also acceptable. Please verify and confirm. Patient is 71y active , still working medical professional, with Hx of Htn and aortic valve replaced in 2000 to manage Aortic Insufficiency. Your prompt response will be greatly appreciated.
Sorry about your diagnosis. Sounds like you are doing OK other than the numbness? I had shooting pain in the general area for a while. I can still "feel it" if I am too active or get dehydrated. I had numbness in my feet for about a week afterwards on and off (especially at night). My doctor put me on neurontin, and it did help. It's actually an epilepsy drug, but there are tons of anecdotal evidence of it helping for other things (off-label). It helps rewire misfiring nerves.
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