Ever since I started taking Zetia and Fenofibrate together as recommended by my DR, I have put on pounds, am more bloated around the belly,a nd have persistent chest pains. I noticed this has occurred ever since I have been on cholesterol lowering meds, but is more noticeable in the past year with the new combination of drugs. I mentioned this to my DR and he said I need the drugs because of my High Cholesterol. What do you think?
Statins work in the liver and every commercial I have seen advises not to take if you have liver problems. Zetia works in the intestines.
Was the Zetia working?
If my memory serves me correctly, MikeS is taking statins and he had a TP. He is far more knowledgeable on the subject than I am and hopefully he will see this post and give his input.
Zetia is part of a class of drugs called cholesterol absorption inhibitors.
AST on upper end of normal at 40. The doctor said to stop the Lipitor...but stay on the Zetia...... and retest in 1-1/2 weeks which he did this past Sept. 30th. His ALP came down to normal at 91, his ALT stayed the same at 79, his AST stayed relatively the same at 42, but his GGTP went quite high at 240. The doctor's office called and told him to come in next week.
If it were me I would give pravastatin a chance, but if I had the same side effects and I could not live with them, I would try something like Zetia. You could also add a fenofibrate like Tricor to lower your TGLs as well, very safe and no side effects. This will help lower your overall number but will not impact your LDL which is you main issue. You really need to get that under 130 with no other risk factors.
I’m a active 68 yr. old women, that has tried 3 different statins. Everyone gave me muscle problems. Then my GP put me on Zetia. Said it would be different. After two months on it, it was worst than the statins. Woke up one morning, couldn’t close my hand. My fingers were so swollen and my both thumb joints would not bend. When I tried to bend them they clicked and was very painful.
I finally went to a specialist in Baltimore who read my history which showed all the meds I was taking and he noticed that I was taking Zetia and told me that he believed Zetia caused chronic coughing in some people; so he looked it up on his computer and sure enough, that was one of the warnings. I stopped the Zetia and the coughing disappeared completely within a couple of weeks. The point here is that medicines, while helping one problem, frequently can cause another.
My wife has been perscribed fentanyl patches and has been told not to eat grapefruit, does this apply to all citrus fruit ie.
I just got off of zetia and welchol. I could not take statins. I tried them all. Used to take Niaspan and fenofibrate but they took me off cause both cause problems in some and had not 'reduced the incidence of cardiac events'. I think they have concluded that neither do Zetia, except when used with a statin, so it is the statin doing the work. I also think Welchol has been shown to not reduce cardiac events too. not sure. I am on Repatha. Third bi weekly shot.
http://www.medhelp.org/posts/Hepatitis-C/Treatment-for-Hep-C--Grapefruit-Juice/show/542498
“It actually can increase some drug levels because of inhibiting a liver metabolic enyzme. However neither interferon or ribavirin is metabolized by that particular enzyme(p450) so it is OK to drink your grapefruit juice. Stay Healthy!
Several of my drugs (Lamictal, Seroquel, & Valium - at a minimum) interact w/ grapefruit. It's on all of the information that comes from the pharmacy and I didn't take it seriously until I got pretty toxic myself. I LOVE grapefruits & grapefruit juice and I miss them a lot. I also tend towards side effects and toxicity.
Wow looks like i should have read the warning label when my doc gave me to take them PRN or as necessary to re convert myself......okay i just went off of the site and read up on the label...they are telling us not to take it with the citrus because it effects how our body absorbs the Multaq for maximum performance of the med...if it were me and i had to take it on a daily basis i probably would stay away from all citrus drinks for sure because you want to give yourself the best shot possible...
This may seem to be a silly question, but has anyone heard from their doctors not to combine methimazole and grapefruit? Online research seems to say it's not flagged as interacting but also notes that no studies have been done to see if it does interact. I was wondering if anyone's doctor had said anything?
My doc is on vacation and I was gifted with a lovely and delicious looking 24 grapefruits.....
Hi Chicky
Watch out for interactions with grapefruit juice and meds. I went on Zoloft in anticipation of beginning treatment. Then read about the grapefruit juice-turns out they use the same enzyme to clear your system so you can get too much of the drug in your system and get liver toxicity. Grapefruit acts that way with many drugs, so check first, then drink up.
i need to know that, what is the interaction between juices of Grapefruit and Hepatitis C? is there any reactions of Grapefruit juice being taken by Hepatitis C patient?
If narigenin is grapefruit then it is definitely not a good idea. I didn't know what narigenin was but, if I had, I would have more strongly advised against it. Don't eat grapefruit while taking Prograf is one of the first things I was told and told many times immediately after transplant.
"Do not consume grapefruit or grapefruit juice during treatment with Prograf unless your doctor has told you do(sic). Prograf can have a dangerous interaction with grapefruit or grapefruit juice.
It went on to mention certain prescription drugs that are affected by eating grapefruit and its juice. Typically, I eat two grapefruits a day! When I called my pharmacist, he said that it wasn't a drug that showed a high incidence of interaction with grapefruit, unlike the cholesterol lowering drugs. (Internet searches clearly showed that there is a connection). The pharmacist did however, say, that I should skip that night's dose and try to taper off.
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