Zetia and grapefruit interaction
Common Questions and Answers about Zetia and grapefruit interaction
zetia
I like to drink grapefruit juice but hear that it can interfere with some prescription medications. Is that true?
Answers from Katherine Zeratsky, R.D., L.D.
Yes. Grapefruit and certain other citrus fruits and products can interfere with several kinds of prescription medications.
Don't take these interactions lightly. Some can cause potentially dangerous health problems.
Ever since I started taking Zetia and Fenofibrate together as recommended by my DR, I have put on pounds, am more bloated around the belly,a nd have persistent chest pains. I noticed this has occurred ever since I have been on cholesterol lowering meds, but is more noticeable in the past year with the new combination of drugs. I mentioned this to my DR and he said I need the drugs because of my High Cholesterol. What do you think?
In contrast to the increased levels of the other medications, the grapefruit juice interaction observed with theophylline and itraconazole was reduced plasma concentrations. The mechanism for this effect has not been determined.
Although the clinical consequence of the grapefruit juice interaction with most of the listed drugs has not been evaluated, increased plasma concentrations of many of these drugs could result in adverse outcomes.
Yes, I understand there is an interaction between victrelis and grapefruit and I learned it on this board too. Then I looked for the confirmatin on that and found it in Victrelis' labeling.
I don't believe either Victrelis or Incevik have been used to treat HIV. They were just approved in May, 2011, for the treatment of Hepatitis C. They are in a class of new drugs that target the specific virus and there are HIV drugs that do the same - but not the same drugs.
No interaction between both drugs. Note that some aliments like citrus, grapefruit extract can increase the potency of some drugs which is considered an interaction.
i need to know that, what is the interaction between juices of Grapefruit and Hepatitis C? is there any reactions of Grapefruit juice being taken by Hepatitis C patient?
can I drink the juice of 1 grapefruit a day, if I am taking metoprolol and fosinopril for blood pressure? My blood pressure is completely controled.
//www.drugs.com/prograf.
There is an interaction between grapefruit and almost every medication known to man. When it come a to mental health medications grapefruit is a very serious danger. I am glad you are ok and have patience because things will go back to as they were. Grapefruit and st. Johns wort are to things to completelt avoid while taking zoloft and/ or other mood balancing/ altering medicines.
This, initially the drug does not completely metabolize and has an extended half-life. This why it is dangerous to take grapefruit juice with certain medications. Follow me on this. You take a substance that reduces the production of these enzymes (say grapefruit juice) and for the first four hours the drug does not fully metabolize. After six hours the grapefruit juice wears off, the liver again starts producing these enzymes, and you take a second dose of the medication.
Several of my drugs (Lamictal, Seroquel, & Valium - at a minimum) interact w/ grapefruit. It's on all of the information that comes from the pharmacy and I didn't take it seriously until I got pretty toxic myself. I LOVE grapefruits & grapefruit juice and I miss them a lot. I also tend towards side effects and toxicity.
If it were me I would give pravastatin a chance, but if I had the same side effects and I could not live with them, I would try something like Zetia. You could also add a fenofibrate like Tricor to lower your TGLs as well, very safe and no side effects. This will help lower your overall number but will not impact your LDL which is you main issue. You really need to get that under 130 with no other risk factors.
The interaction caused by grapefruit compounds lasts for up to 24 hours and its effect is the greatest when the juice is ingested with the drug or up to 4 hours before the drug. [10]
It is demonstrated for the first time that lemon juice significantly inhibits by 60 ± 3% the CYP3A4-mediated oxidation
http://cat.inist.fr/?
Naringenin interferes with drugs, so you should not take it while on treatment. If you google Naringenin drug interaction or grapefruit drug interaction, you will find a lot of info on the subject.
The substance naringin/ naringenin in grapefruit interacts with medications, mostly enhancing the drugs in your blood stream. If you google grapefruit and drug interaction, you will get a lot of info.
Milk thistle helps clean your liver of substances, it's kind of a 'liver flush'. When you are on treatment, the last thing you want is the treatment drugs being flushed out of your liver.
Grapefruit and pommelos only are forbidden because of interaction with meds. Pommelo is genetically a grapefruit cross. All other citrus are fine. Literature that recommends grapefruit is not talking about fresh fruit or juice but chemical extracts from grapefruit. I don't know which ones they're playing with but it would never be fresh fruit or juice.
One thought, did you take anything that may have had a poor interaction with your simvistatin? Grapefruit for example is something that needs to be avoided while taking statins. Grapefruit contains the compound bergamottin, which interacts with certain enzyme systems in the body, such as cytochrome P-450 and P-glycoprotein. These enzyme systems are responsible for breaking down statins, as well as other drugs, into more usable chemicals and transporting them in the body.
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