The LD50 for Water is 90g/kg. But when does nerve damage occur, if you trink too much water at once?
When does it become toxic?
Empirical data is also appreciated...
You are talking about Chantix (Varenicline tartrate) that should be available worldwide. If not, ask your doctor for other suggestion for quitting smoking.
Hello, Chantix (varenicline) and Zyban (bupropion) are the only two non-nicotine medications approved by the U.S. Food and Drug Administration (FDA) for smoking cessation; both are available in pill form and only by prescription. Chantix received FDA approval in 2006; Zyban was approved in 1997. These drugs can be effective tools, but users need to be aware of some potentially serious side effects. You can try that and they are very cheap in some pharmacy's.
However, Italian researchers have found that the LD50 (the lethal dose at which half of the animals die) of glucosamine sulfate is 8000 mg/kg. In humans this would be equivalent to ingesting over 500,000 mg at one time or 1,000 pills each containing 500 mg.
I hope this is useful... I got the idea from the site that max safe dose is 1500mg, and your dog had twice that much. You may want to see the vet anyway, even tho it says in the previous paragraph that a lethal dose is 8000mg.
my dad is 83 yrs old, has emphysema, copd everything...hes on ox, however he still struggles to breathe, won't allow anyone to go into the doctors office with him ! I know he is in stage 4, how long does that last? its been like this for a couple of years, he has difficulty even walking across the room and says that its a task to urinate. is there anything we can do as a family to make him more comfortable?
opiates will make your spew, but i dont think the codeine even in high doses makes you sick, iv had 240mg of codeine before and it just makes you feel real high for a couple of hours, ulcers would be causing him pain,so im not so sure if its ulcers.HOw many is he taking at one time?
This only becomes an issue if you are taking mega-doses of those vitamins and lose a lot of weight - suddenly, your body could be overdosed - there is an LD50 listing for vitamin A of 2000 mg/kg - LD = lethal dose, LD50 = 50% of the population will die at that dose, 2000 milligrams per kilogram of body weight.
Anyone who tells you that herbs will not hurt you is just wrong.
I know that this forum isn't adequate for my question but I am new to this site please forgive me for this.
I am 17 years old, and 80 kg.
My issue is I have just taken accidentally 10 grams of paracetamol aka acetaminophen I've just read that the ld50 is >250mg/kg so by this it means that the dose for me to die is 20 grams.
Will I be safe for the next 24 hours because I can't seek any medical help for this time, what should I do? I am really scared.
He should do this with your strong encouragement, with the help of his doctor and prescription of nicotine replacement therapy along with at least one other smoking cessation medicine such as Wellbutrin® (buproprion) or Chantix® (varenicline), counseling and group support, both at home and in his workplace.
This is a critical moment for your father.
Some meds need to be separated by a short period of time. I guess these are more specifically SSRI's and MAOI's. I didn't see a major problem with the meds being taken consecutively. This should always be at the discretion of ones doctor though.
I guess I neglected to emphasize the importance of only ever making medication changes after consultation with the treating physician.
There are a number of factors to consider when changing meds. Withdrawal is only one.
(which have now been restricted to clinic/in-person use only, which I wholly approve of BTW), could very well stand a chance of approaching LD50 for an opiate naive person.
6 pills in 48 hours for a relatively opiate naive person could also enter ld50 territory.
Weight doesn't much to do with propensity to die from N dose.
When I read the LD50 dose is at 9.5grams and I exceeded that for at least three days in a row. From what I read I really won't know if I have killed myself until Saturday or Sunday.
Therefore you won’t need to worry about its metabolites lingering in circulation for a longer duration than varenicline itself. In the vast majority of users, average elimination should occur within 5 to 7 days after complete discontinuation.""
5 to 7 days is how long it is SUPPOSED to last at most. How long has it been? You are saying 5 months??
Tell us your symptoms and what is going on. Let's talk.
The serious problems — including reports of completed suicides, suicide attempts, aggression and hostility and depression — had been mixed among some 26,000 records of non-serious side effects such as nausea and rashes, with some dating back to 2006, the year Chantix, or varenicline, was approved.
They echo previous claims that the drug can induce extreme reactions in people trying to quit cigarettes, including vivid nightmares, crippling depression and sudden, violent outbursts.
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