That trial, run by Caprisa, an AIDS research center in Durban, showed for the first time that tenofovir gel protected women against H.I.V. It also showed that the roughly 450 women in the survey who did not have herpes were even better protected against it than they were against the AIDS virus.
Over all, the gel reduced H.I.V. infections by 39 percent.
GS-7340 - so this is another formulation of Tenofovir by Gilead Science. The timing of this new pro-drug is interesting. Most likely Gilead Science has been sitting on this for a while. Just like it has been sitting on Tenofovir as a drug for HBV for years.
There is an Australian company that is also developing a new pro-drug of Tenofovir, it will begin clinical trial in China next year.
Gilead has amassed a fortune from its HIV drugs.
Get the test done for HBSag in iu/ml from ILBS ( institue of liver and billary science New delhi ) . The current results of your shows it is greater than 250iu/ml but does not show the exact value . Also get the HBV DNA & fibroscan done. The fibroscan will determine the health of your liver . .
If your hbsag is less than 1000iu/ml then you have very high chances of clearing the virus with interferon treatment .
· In vivo antiviral activity of REP 2139-Ca combined with tenofovir disoproxil fumarate and entecavir (poster THU-177).
· Immunostimulatory properties of REP 2139 and other NAP compounds (poster THU-204).
Replicor’s presentations will be available on the company’s website at the end of the conference at www.replicor.com/science/conference-presentations. For the 2016 EASL Meeting: http://ilc-congress.eu/.
are these drugs antiviral? how long am i going to be on them? i did liver scan recently where a gel was poured on my right side very close to the ribs and a piece of equipment is rolled over it though the report is not out yet. Is this same thing as fibroscan? pls how safe is my wife and children?
immune tollerant, no treatment needed (high hbvdna, normal alt, no liver damage)
inactive hbv, hbvdna undetactable, normal alt/ast, you might use alinia which lowers hsag and hbeag, it has no notable sides and no resistance, it is already used from 2000 or 2002 for other diseases and it is on trial for many viruses like hcv, influenza, early hbv trials have the highest rates of seroconvertion
active hbv, hbvdna over 2000iu/ml, abnormal alt/ast, liver damage, tenofovir, entecavir, interferon,
New GI: Do you want Tenofovir or Peginterferon? My new GI said she will try to switch me from Entecavir and either put me on Tenofovir or Peginterferon. I ask for a combo and she told me that Tenofovir and Peginterferon does the same thing. Is that even true?
· In vivo antiviral activity of REP 2139-Ca combined with tenofovir disoproxil fumarate and entecavir (poster THU-177).
· Immunostimulatory properties of REP 2139 and other NAP compounds (poster THU-204).
Replicor’s presentations will be available on the company’s website at the end of the conference at www.replicor.com/science/conference-presentations. For the 2016 EASL Meeting: http://ilc-congress.eu/.
I visited a sex worker the other day, and whilst showering i opened the shower gel bottle and then used the same hand to wash my penis glans. Can hiv been transmitted in this way?
In china, we can get 2 types of TDF, one is from HongKong which is imported from Gilead Science USA, the other one is from India Cipla company.None of them are legal in China currently.
Would like to ask, if Tenofovir Cipla could be worse than Viread USA? Which one should I take for the rest of my life? What's your guys advice? BTW, the US one is 6 times more expensive than the India one.
That is actually not much better than tenofovir vs tenofovir disoproxil fumarate, the actual substance in Viread. It is 50 times more potent than tenofovir.
It is all this improper simplification of callling viread tenofovir.
Tenovovir, if it would be given orally, would have no effect on HBV.
TEnofovir if given intravenously or sc would still have almost no effect on HBV in the liver. the substance has a high negative charge and cannot easlily penetrate cell membranes.
(20) The T69S insertion mutations, associated with resistance to multiple nucleoside analogues, are associated with resistance to tenofovir as well. Tenofovir resistance conferred by the T69S mutation or by multiple thymidine analogue resistance mutations appears to be multiplied if the M184V mutation is replaced by wild-type.(21) The K65R mutation, which may be selected by prior nucleoside analogue therapy, is associated with a modest decrease in sensitivity to tenofovir.
Association of Higher Plasma Vitamin D Binding Protein and Lower Free Calcitriol Levels with Tenofovir Disoproxil Fumarate Use and Plasma and Intracellular Tenofovir Pharmacokinetics: Cause of a Functional Vitamin D Deficiency?
"The finding of a 26% increase in vitamin D binding protein and a 42% decrease in free 1,25-OH(2)D between the lowest and highest quintiles of plasma tenofovir has not been previously reported.
In chronic hepatitis B, PD-1 and CTLA-4 as inhibitory T cell molecules and FoxP3 as regulatory T cell marker are down-regulated during initial 6 month tenofovir therapy, which could restore HBV-specific T cell function during tenofovir antiviral therapy. Long-term effects of tenofovir on host immune system are needed to be elucidate.
The following is a paper from doctors in Francel. It said you can breastfeed whilst your are on Tenofovir because "Tenofovir is not absorbed in the breast milk". However, I have googled and cannot find any reference to this claim. All the best to you and your baby.
Clin Res Hepatol Gastroenterol.
2011 Jun 7. [Epub ahead of print]
Hepatitis B virus infection and pregnancy.
Pol S, Corouge M, Fontaine H.
Hi stef good day. U still there?? I have some question stef about taking tenofovir because i dont know what to do. Im start taking tenofovir september 2020 and i notice that february my urine have bubles until now my urine still foamy or bubles but in evening is normal.
Tenofovir can cause proteina stef??
tenofovir, no resistance
entecavir, 1,5% resistance but cannot be used on those using lamivudine because in this case resistance can go higher than 50%
interferon
if i had a doctor prescribing me such rubbish useless toxic.....i d destroy his life....
I am on tenofovir from March 2012 when i am pregnant at week 32. At that time i had hbs and hbe both positive.
Hi All,
Is there a way I can have a prescription from a doctor when buying tenofovir online? Here in the Philippines, the drug is not yet available and the doctors are not prescribing it since it is not available. I'm planning to take tenofovir but having trouble in getting prescription, so i cannot order online.
Please advise.
I took tenofovir from the 3rd trimester and my baby is fine till now but i stopped using it when she 2 months and start again 2 days ago since.
hbv has no symptoms, you may even be dying and feel nothing
tenofovir improves kideys function especially tenofovir+telbivudine in those with kidneys function.
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