The study, by researchers from the National Institutes of Health, Gilead Sciences Inc. and universities in Belgium and Italy, suggests that the microbicide gel, which was originally developed to fight AIDS in Africa, could lower the incidence of herpes in many women.
“This could be incredibly helpful,” said Dr. Jeanne Marrazzo, a herpes expert from the University of Washington’s medical school. “Protection that a woman can control is the holy grail in this field.
If it can be shown to work safely in women, GML might provide the first easy route to a microbicide -- a gel or a cream that women could use vaginally to protect themselves from infection with the human immunodeficiency virus, or HIV, which causes AIDS.
HIV infects 33 million people globally and has killed 25 million. It is transmitted sexually, in blood and breast milk. In Africa, it is most commonly passed during heterosexual contact.
are these drugs antiviral? how long am i going to be on them? i did liver scan recently where a gel was poured on my right side very close to the ribs and a piece of equipment is rolled over it though the report is not out yet. Is this same thing as fibroscan? pls how safe is my wife and children?
I don't think so. I know that VivaGel is a microbicide, which was initially designed to prevent HIV infection. I don't think it was shown to be successful in trials. I'm not sure of its effect with herpes, but I'm fairly sure it will be preventitive, not therepeutic.
will be interesting to see what comes out of this.
That is actually not much better than tenofovir vs tenofovir disoproxil fumarate, the actual substance in Viread. It is 50 times more potent than tenofovir.
It is all this improper simplification of callling viread tenofovir.
Tenovovir, if it would be given orally, would have no effect on HBV.
TEnofovir if given intravenously or sc would still have almost no effect on HBV in the liver. the substance has a high negative charge and cannot easlily penetrate cell membranes.
(20) The T69S insertion mutations, associated with resistance to multiple nucleoside analogues, are associated with resistance to tenofovir as well. Tenofovir resistance conferred by the T69S mutation or by multiple thymidine analogue resistance mutations appears to be multiplied if the M184V mutation is replaced by wild-type.(21) The K65R mutation, which may be selected by prior nucleoside analogue therapy, is associated with a modest decrease in sensitivity to tenofovir.
Association of Higher Plasma Vitamin D Binding Protein and Lower Free Calcitriol Levels with Tenofovir Disoproxil Fumarate Use and Plasma and Intracellular Tenofovir Pharmacokinetics: Cause of a Functional Vitamin D Deficiency?
"The finding of a 26% increase in vitamin D binding protein and a 42% decrease in free 1,25-OH(2)D between the lowest and highest quintiles of plasma tenofovir has not been previously reported.
The following is a paper from doctors in Francel. It said you can breastfeed whilst your are on Tenofovir because "Tenofovir is not absorbed in the breast milk". However, I have googled and cannot find any reference to this claim. All the best to you and your baby.
Clin Res Hepatol Gastroenterol.
2011 Jun 7. [Epub ahead of print]
Hepatitis B virus infection and pregnancy.
Pol S, Corouge M, Fontaine H.
Hi stef good day. U still there?? I have some question stef about taking tenofovir because i dont know what to do. Im start taking tenofovir september 2020 and i notice that february my urine have bubles until now my urine still foamy or bubles but in evening is normal.
Tenofovir can cause proteina stef??
tenofovir, no resistance
entecavir, 1,5% resistance but cannot be used on those using lamivudine because in this case resistance can go higher than 50%
interferon
if i had a doctor prescribing me such rubbish useless toxic.....i d destroy his life....
I am on tenofovir from March 2012 when i am pregnant at week 32. At that time i had hbs and hbe both positive.
Hi All,
Is there a way I can have a prescription from a doctor when buying tenofovir online? Here in the Philippines, the drug is not yet available and the doctors are not prescribing it since it is not available. I'm planning to take tenofovir but having trouble in getting prescription, so i cannot order online.
Please advise.
I took tenofovir from the 3rd trimester and my baby is fine till now but i stopped using it when she 2 months and start again 2 days ago since.
hbv has no symptoms, you may even be dying and feel nothing
tenofovir improves kideys function especially tenofovir+telbivudine in those with kidneys function.
http://pharmacychecker.com/Pricing.asp?DrugName=Tenofovir+Disoproxil+Fumarate&DrugId=59463&DrugStrengthId=105019
or
http://www.northdrugstore.com/buy-Viread.html
maybe this will help ... but have to check before because some fake drugs can be sell over the internet.
tenofovir is the oldest drug among hbv drug since we share the same drugs as hiv, it is the most potent and generics are on the market.
HBVDNA is not detectable, Fiboscan is normal. initially i went through PegIntreforen+ Tenofovir for 40 weeks in 2012 then i switch to only Tenofovir. Now it 3 yrs and 4 month on Tenofovir.
Last week my doctor told that you HbeAg should be non reactive after 2 yrs of Tenofovir but since it over 3 years so might be Tenofovir resistance So you need to change my medicine.
Please suggest me what i do.
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