As far as I know, the phase III clinical trials of E75 vaccine are still ongoing (the trial that will ultimately lead to FDA approval, if proven effective). The previous studies and phase I to phase II trials for his vaccine have shown promising results. For now, targeting the Her2Neu expression will still involve drugs like Herceptin (trastuzumab) or Tykerb (lapatinib).
The clinical trials that they were running, and were prematurely stopped because they were very unlikely to reach their endpoints, sound strangely designed from the start.
From memory they specifically selected people who had previously taken antivirals previously, and whose antivirals had failed them.
They never tested them on regular HBV patients.
Seeing the results of this now that it's on the market will be very interesting. I hope that there is some information posted in this forum.
hi -- a few weeks ago there was a guy who posted here looking for user-friendly clinical trials sites. He was getting medical help outside of the U.S. I can't find his post....so thought I'd write a new one hoping he'll find this. I found this site today and thought of him.
http://www.centerwatch.com/patient/pns/patemail.
I keep hearing people talking about clinical trials but I haven't been able to find out about any. I've called my gastro doctor and other doctors that I have and no one knows anything about them. Do any of you know of any clinical trials for Telaprivir?
It has been safely and successfully used in china for over 20 yrs.There are current clinical trials in the US in Ca. and Fl. showing great promise. Do you have any knowledge of this treatment.? Are there any other trials or treatments of any kind available now for preventing or reducing fibrosis in post tx hepC that i can use. Ive heard low dose maintenance interferon can reduce fibrosis. Is that true?
I just completed tx through a clinical trial at Duke. I know that's quite a drive for you, but I'll tell you my care at the Hepatology Clinic there has been awesome! I don't know if any other NC hospitals, besides Duke and Chapel Hill, are involved in trials.
Do look up the clinicaltrials.gov site and I think you can narrow it down to your state. You can also go to Duke's website and they list ongoing current clinical trials by the disease.
There are literally hundreds of different clinical trials for HCV right now… you’ll need to be more specific regarding the trial drug. Go back to whoever referred you to it, and ask them the name, or better yet, the NCT number and someone in here might be able to help. You can search the clinical trial database by going to:
http://clinicaltrials.
The vaccine is not registered yet for general use. Clinical trials are ongoing in Cuba and Bangladesh and new trials should start in Brazil and Europe next year.
(I just copy a part of the study document, it is quite big file)
The nasal vaccine candidate (NASVAC), comprising hepatitis B virus (HBV) surface
(HBsAg) and core antigens (HBcAg), has been shown to be highly immunogenic in animal models.
EYP001, the first product developed under this program, which we licensed from Poxel in early 2015, is nearing the end of its regulatory toxicology trials. Clinical trials are scheduled to begin in early 2016.”
ENYO Pharma’s goal is to complete all required studies to submit a Clinical Trial Application to begin phase 1 clinical trials in spring 2016 on healthy volunteers and begin treating patients with chronic HBV in phase 2 trials by 2017.
Nor is it clear that they will have a similar business plan of publicly posting ongoing trials. I have only heard that there is a plan to move ahead with recruitment of the BMS/PSI EXTENSION that has been in progress for some months. I believe this is already listed under the ongoing trial.
I was under the impression, and I would have to check some of the old links from my Medhelp journal, that most studies like Neutrino were awaiting outcomes of Quantum and other trials.
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